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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_2270 [new locus tag: SAUSA300_RS12550 ]
  • pan locus tag?: SAUPAN005803000
  • symbol: glvC
  • pan gene symbol?: glvC
  • synonym:
  • product: PTS system, arbutin-like IIBC component

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_2270 [new locus tag: SAUSA300_RS12550 ]
  • symbol: glvC
  • product: PTS system, arbutin-like IIBC component
  • replicon: chromosome
  • strand: -
  • coordinates: 2439955..2441559
  • length: 1605
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGAATGCGATAAAGCGTTTCGGTAGTGCAATGATTGTACCGGTATTAATGTTCGCTTTC
    TTTGGGATAGTGCTTGGCTTTGCGACATTATTTAAAAATCCTACAATCATGGGGAGTTTA
    GCAGATCAACATACGTTTTGGTTTAAATTTTGGTCAGTAATAGAATCTGGTGGCTGGGTT
    ATTTTTACGCATATGGAAGTTGTATTTGTTGTAGGTCTACCACTTTCTTTAGCTAAAAAA
    GCACCAGGTCATGCAGCACTTGCAGCATTGATGGGTTACTTAATGTTTAATACATTTATA
    AATGCCATTTTAACACAATGGCCACATACGTTTGGCGCTAATTTAGAAAAAGGCGTTGAA
    AATGTACCTGGTTTAAAATCAATTGCAGGTATTGCCACATTGGATACGAATATTCTAGGT
    GGTATTATTATTTCAGCTATTATTACTTGGATTCACAATAGATACTATAGTAAACGATTA
    CCAGAAATGGTTGGTGTATTCCAAGGTTTAACATTTGTAGTTACGATTTCATTTTTTGTG
    ATGTTACCATTAGCAGCAATTACTTGTGTTATTTGGCCAACTGTTCAGCACGGTATTGGT
    TCAATGCAACACTTTATCATTGCTTCAGGCTATATCGGTGTATGGTTGTATCACTTCTTA
    GAACGTGTATTAATACCAACAGGATTACATCACTTTATTTATGCACCAATTGAAGTTGGA
    CCAGTAGTAGTCAATCACGGCTTGAAAGCTGAATGGTTACAACATTTAAATGAGTTTGCT
    AAGAGTACTAAGCCATTAAAAGAGCAATTCCCTTATGGCTTTATGCTTCAAGGAAATGGG
    AAAGTATTTGGATGTTTAGGTATTGCTTTAGCAATGTATGCTACGACACCTAAAGAAAAT
    CGTAAAAAGGTGGCGGCACTACTTATTCCTGCCACATTAACAGCAGTCGTTGTAGGTATT
    ACTGAGCCATTAGAGTTTACATTCTTATTCATCGCACCATACTTATTTGTTTTACACGCA
    GTTTTAGCAGCATCAATGGATACTTTAATGTACGCATTTGGTGTTGTAGGTAACATGGGT
    GGTGGCTTGTTAGACTTTATTTCAACAAACTGGTTGCCATTAGGTAAAGAACATTGGGGT
    ACTTATGTTGCACAAGTTATTATCGGTCTGATATTTGTAGCGATTTACTTCTTCTTATTC
    AGATTCTTAATTTTGAAATTTGATATTCCATTACCTGGACGTAAGAAAACAGAAGAGGAA
    GTTAAATTATTTTCTAAGCAAGATTACAAAAATAAAAAAGGTGATAGCGTAGATTCTAAA
    CGTGCTTCATCTGGTAATGAATACGAAGACAAAGCTGCATATTACCTCGACGGTTTAGGC
    GGCAAAGAAAATATCAAAGATGTTACTAACTGTACAACAAGATTACGCTTAACTGTTTAT
    GATGAAAGTAAAGTTGCAGATACGGAATATTTCACGCATCAACAAATGGCACACGGATTA
    GTAAAGAGTGGTAAGAGTATCCAAGTTGTAGTAGGTATGACAGTACCACAAGTTCGTGAA
    GCATTTGAACAAATGGTTGAGGATCAATCGTCCGAAGATAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1605

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAUSA300_2270 [new locus tag: SAUSA300_RS12550 ]
  • symbol: GlvC
  • description: PTS system, arbutin-like IIBC component
  • length: 534
  • theoretical pI: 8.64496
  • theoretical MW: 59329.2
  • GRAVY: 0.366105

⊟Function[edit | edit source]

  • reaction:
    EC 2.7.1.69?  ExPASy
    Transferred entry: 2.7.1.191, 2.7.1.192, 2.7.1.193, 2.7.1.194, 2.7.1.195, 2.7.1.196, 2.7.1.197, 2.7.1.198, 2.7.1.199, 2.7.1.200, 2.7.1.201, 2.7.1.202, 2.7.1.203, 2.7.1.204, 2.7.1.205, 2.7.1.206, 2.7.1.207 and 2.7.1.208
  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, alpha-glucoside-specific IIBC component (TIGR02005; EC 2.7.1.69; HMM-score: 966.1)
    and 11 more
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, maltose and glucose-specific IIBC component (TIGR02004; EC 2.7.1.69; HMM-score: 290.6)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, glucose-specific IIBC component (TIGR02002; EC 2.7.1.69; HMM-score: 278.1)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, N-acetylglucosamine-specific IIBC component (TIGR01998; EC 2.7.1.69; HMM-score: 277.2)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, maltose and glucose-specific subfamily, IIC component (TIGR00852; HMM-score: 237.7)
    Signal transduction Signal transduction PTS PTS system, maltose and glucose-specific subfamily, IIC component (TIGR00852; HMM-score: 237.7)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, IIBC component (TIGR02003; EC 2.7.1.69; HMM-score: 162)
    PTS system, beta-glucoside-specific IIABC component (TIGR01995; EC 2.7.1.69; HMM-score: 57.8)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, glucose-like IIB component (TIGR00826; EC 2.7.1.69; HMM-score: 56)
    Signal transduction Signal transduction PTS PTS system, glucose-like IIB component (TIGR00826; EC 2.7.1.69; HMM-score: 56)
    PTS system, sucrose-specific IIBC component (TIGR01996; EC 2.7.1.69; HMM-score: 52.5)
    PTS system, trehalose-specific IIBC component (TIGR01992; EC 2.7.1.69; HMM-score: 49.5)
  • TheSEED  :
    • PTS system, maltose-specific IIB component (EC 2.7.1.69)
    • PTS system, maltose-specific IIC component
  • PFAM:
    PTS_EIIC (CL0493) PTS_EIIC; Phosphotransferase system, EIIC (PF02378; HMM-score: 221.7)
    and 2 more
    no clan defined PTS_EIIB; phosphotransferase system, EIIB (PF00367; HMM-score: 53.9)
    Ldr_toxin; Toxin Ldr, type I toxin-antitoxin system (PF13940; HMM-score: 12.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 10
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: 0.5
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.065349
    • TAT(Tat/SPI): 0.00115
    • LIPO(Sec/SPII): 0.019006
  • predicted transmembrane helices (TMHMM): 10

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNAIKRFGSAMIVPVLMFAFFGIVLGFATLFKNPTIMGSLADQHTFWFKFWSVIESGGWVIFTHMEVVFVVGLPLSLAKKAPGHAALAALMGYLMFNTFINAILTQWPHTFGANLEKGVENVPGLKSIAGIATLDTNILGGIIISAIITWIHNRYYSKRLPEMVGVFQGLTFVVTISFFVMLPLAAITCVIWPTVQHGIGSMQHFIIASGYIGVWLYHFLERVLIPTGLHHFIYAPIEVGPVVVNHGLKAEWLQHLNEFAKSTKPLKEQFPYGFMLQGNGKVFGCLGIALAMYATTPKENRKKVAALLIPATLTAVVVGITEPLEFTFLFIAPYLFVLHAVLAASMDTLMYAFGVVGNMGGGLLDFISTNWLPLGKEHWGTYVAQVIIGLIFVAIYFFLFRFLILKFDIPLPGRKKTEEEVKLFSKQDYKNKKGDSVDSKRASSGNEYEDKAAYYLDGLGGKENIKDVTNCTTRLRLTVYDESKVADTEYFTHQQMAHGLVKSGKSIQVVVGMTVPQVREAFEQMVEDQSSEDK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulators: GlvR* (activation) regulon, CcpA regulon
    GlvR*(TF)important in Maltose utilization; RegPrecise 
    CcpA(TF)important in Carbon catabolism; RegPrecise 

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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