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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_2307 [new locus tag: SAUSA300_RS12750 ]
  • pan locus tag?: SAUPAN005869000
  • symbol: SAUSA300_2307
  • pan gene symbol?: hrtB
  • synonym:
  • product: ABC transporter permease

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_2307 [new locus tag: SAUSA300_RS12750 ]
  • symbol: SAUSA300_2307
  • product: ABC transporter permease
  • replicon: chromosome
  • strand: -
  • coordinates: 2479699..2480754
  • length: 1056
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAAATTAGCGATAAAAGAGATTATGTTTTACAAATTTCGTTATATTTTAATCACATTA
    ATCATTCTTTTATTAAGTATTATGGTGTTATTTATTAGTGGTTTAGCTCAAGGGCTTGGT
    AGGGAGAATATTTCGTTATTTGAACACTTTGATAATGATGAATATGTTGTTCAAAAAATG
    AAAGAGCCGCAAATTGAGAAATCGCAACTTAGTGATACGCAACAGAATCAAATTAAAAAG
    GTAATTCATCAAGAACCATATAAAATGAATATTCAAACATTGAAATTATCTAATAAAGAA
    CAAGATGTGATTACAATGAATGACGTTAAACAACAACGCATACAACTTAAAAAAGGTGAT
    TATCCTAAAAATGCTCATGAGGTCGCTATTAATGATAAGTTAGCTGCAGACAACATTAGA
    GTCGGGGATAGATTACATTTTAAAAATAATTCAACTAGTTATAGAGTTTCTGGTATTTTA
    AACGACACAATGTATGCGCATAGTTCCATTGTGCTATTGAACGATAACGGATTTAATGCA
    TTGAATAAGGTTAATACGGCATTTTATCCAGTGAAAAATTTAACACAACAACAACGTGAT
    GAGCTTAATAAAATAAATGACGTTCAAGTTGTGAGTGAAAAAGATTTAACAGGTAATATT
    GCGAGTTATCAAGCAGAGCAAGCACCGTTAAATATGATGATTGTTAGTTTGTTTGCTATT
    ACAGCAATCGTTCTAAGTGCATTTTTCTATGTTATGACGATTCAAAAAATATCACAAATT
    GGCATTTTGAAAGCAATTGGTATTAAGACAAGACATTTATTGAGTGCGTTAGTTTTACAA
    ATTTTAACACTAACAATAATTGGGGTAGGTATTGCTGTGATCATCATAGTAGGACTATCA
    TTTATGATGCCGGTAACGATGCCTTTTTACTTAACAACGCAAAATATTTTATTAATGGTG
    GGGATATTTATATTAGTAGCGATTTTAGGTGCCTCACTATCATTTATCAAATTATTTAAA
    GTGGATCCTATCGAAGCAATTGGAGGTGCAGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1056

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAUSA300_2307 [new locus tag: SAUSA300_RS12750 ]
  • symbol: SAUSA300_2307
  • description: ABC transporter permease
  • length: 351
  • theoretical pI: 9.58764
  • theoretical MW: 39481.3
  • GRAVY: 0.265242

⊟Function[edit | edit source]

  • TIGRFAM:
    acidobacterial duplicated orphan permease (TIGR03434; HMM-score: 32.9)
    and 1 more
    Metabolism Transport and binding proteins Other ABC exporter transmembrane subunit, DevC protein (TIGR01185; HMM-score: 17.2)
  • TheSEED  :
    • Heme efflux system permease HrtB
    Iron acquisition and metabolism Iron acquisition and metabolism - no subcategory Heme, hemin uptake and utilization systems in GramPositives  Heme efflux system permease HrtB
  • PFAM:
    no clan defined MacB_PCD; MacB-like periplasmic core domain (PF12704; HMM-score: 33.2)
    BPD_transp_1 (CL0404) FtsX; FtsX-like permease family (PF02687; HMM-score: 26.8)
    and 1 more
    no clan defined DUF1195; Protein of unknown function (DUF1195) (PF06708; HMM-score: 11.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0
    • Signal peptide possibility: 0.5
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.220691
    • TAT(Tat/SPI): 0.001317
    • LIPO(Sec/SPII): 0.060633
  • predicted transmembrane helices (TMHMM): 4

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKLAIKEIMFYKFRYILITLIILLLSIMVLFISGLAQGLGRENISLFEHFDNDEYVVQKMKEPQIEKSQLSDTQQNQIKKVIHQEPYKMNIQTLKLSNKEQDVITMNDVKQQRIQLKKGDYPKNAHEVAINDKLAADNIRVGDRLHFKNNSTSYRVSGILNDTMYAHSSIVLLNDNGFNALNKVNTAFYPVKNLTQQQRDELNKINDVQVVSEKDLTGNIASYQAEQAPLNMMIVSLFAITAIVLSAFFYVMTIQKISQIGILKAIGIKTRHLLSALVLQILTLTIIGVGIAVIIIVGLSFMMPVTMPFYLTTQNILLMVGIFILVAILGASLSFIKLFKVDPIEAIGGAE

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • data available for N315

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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