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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus USA300_FPR3757
- locus tag: SAUSA300_RS01775 [old locus tag: SAUSA300_0334 ]
- pan locus tag?: SAUPAN001868000
- symbol: SAUSA300_RS01775
- pan gene symbol?: mepR
- synonym:
- product: multidrug efflux MATE transporter transcriptional repressor MepR
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SAUSA300_RS01775 [old locus tag: SAUSA300_0334 ]
- symbol: SAUSA300_RS01775
- product: multidrug efflux MATE transporter transcriptional repressor MepR
- replicon: chromosome
- strand: +
- coordinates: 386927..387346
- length: 420
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Location: NC_007793 (386927..387346) NCBI
- BioCyc: SAUSA300_RS01775 BioCyc
- MicrobesOnline: see SAUSA300_0334
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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361ATGGAATTCACTTATTCGTATTTATTTAGAATGATTAGTCATGAGATGAAACAAAAGGCT
GATCAAAAGTTAGAGCAATTTGATATTACAAATGAGCAAGGTCATACGTTAGGTTATCTT
TATGCACATCAACAAGATGGACTGACACAAAATGATATTGCTAAAGCATTACAACGAACA
GGTCCAACTGTCAGTAATTTATTAAGGAACCTTGAACGTAAAAAGCTGATCTATCGCTAT
GTCGATGCACAAGATACGAGAAGAAAGAATATAGGGCTGACTACCTCTGGGATTAAACTC
GTAGAAGCATTCACTTCGATATTTGATGAAATGGAACAAACACTCGTATCGCAGTTATCT
GAAGAAGAAAATGAACAAATGAAAGCAAACTTAACTAAAATGTTATCTAGTTTACAATAA60
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420
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SAUSA300_RS01775 [old locus tag: SAUSA300_0334 ]
- symbol: SAUSA300_RS01775
- description: multidrug efflux MATE transporter transcriptional repressor MepR
- length: 139
- theoretical pI: 6.26722
- theoretical MW: 16172.2
- GRAVY: -0.669784
⊟Function[edit | edit source]
- ⊞TIGRFAM: homoprotocatechuate degradation operon regulator, HpaR (TIGR02337; HMM-score: 40.9)and 5 more
- TheSEED: see SAUSA300_0334
- ⊞PFAM: HTH (CL0123) MarR_2; MarR family (PF12802; HMM-score: 38.6)MarR; MarR family (PF01047; HMM-score: 38.1)and 19 more
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
- genes regulated by MepR*, TF important in Multidrug resistance: see SAUSA300_0334
⊟Localization[edit | edit source]
⊟Accession numbers[edit | edit source]
- GI: 446319561 NCBI
- RefSeq: WP_000397416 NCBI
- UniProt: see SAUSA300_0334
⊟Protein sequence[edit | edit source]
- MEFTYSYLFRMISHEMKQKADQKLEQFDITNEQGHTLGYLYAHQQDGLTQNDIAKALQRTGPTVSNLLRNLERKKLIYRYVDAQDTRRKNIGLTTSGIKLVEAFTSIFDEMEQTLVSQLSEEENEQMKANLTKMLSSLQ
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: MepR* see SAUSA300_0334
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available