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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus USA300_FPR3757
- locus tag: SAUSA300_RS03890 [old locus tag: SAUSA300_0722 ]
- pan locus tag?: SAUPAN002642000
- symbol: SAUSA300_RS03890
- pan gene symbol?: murB
- synonym:
- product: UDP-N-acetylenolpyruvoylglucosamine reductase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SAUSA300_RS03890 [old locus tag: SAUSA300_0722 ]
- symbol: SAUSA300_RS03890
- product: UDP-N-acetylenolpyruvoylglucosamine reductase
- replicon: chromosome
- strand: -
- coordinates: 802504..803427
- length: 924
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Location: NC_007793 (802504..803427) NCBI
- BioCyc: SAUSA300_RS03890 BioCyc
- MicrobesOnline: see SAUSA300_0722
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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901GTGATAAATAAAGACATCTATCAAGCTTTACAACAACTTATCCCAAATGAAAAAATTAAA
GTTGATGAACCTTTAAAACGATACACTTATACTAAAACAGGTGGTAATGCCGACTTTTAC
ATTACCCCTACTAAAAATGAAGAAGTACAAGCAGTTGTTAAATATGCCTATCAAAATGAG
ATTCCTGTTACATATTTAGGAAATGGCTCAAATATTATTATCCGTGAAGGTGGTATTCGC
GGTATTGTAATTAGTTTATTATCACTAGATCATATCGAAGTATCTGATGATGCGATAATA
GCCGGTAGCGGCGCTGCAATTATTGATGTCTCACGTGTTGCTCGTGATTACGCACTTACT
GGCCTTGAATTTGCATGTGGTATTCCAGGTTCAATTGGTGGTGCAGTGTATATGAATGCT
GGCGCTTATGGTGGCGAAGTTAAAGATTGTATAGACTATGCGCTTTGCGTAAACGAACAA
GGCTCGTTAATTAAACTTACAACAAAAGAATTAGAGTTAGATTATCGTAATAGCATTATT
CAAAAAGAACACTTAGTTGTATTAGAAGCTGCATTTACTTTAGCTCCTGGTAAAATGACT
GAAATACAAGCTAAAATGGATGATTTAACAGAACGTAGAGAATCTAAACAACCTTTAGAG
TATCCTTCATGTGGTAGTGTATTCCAAAGACCGCCTGGTCATTTTGCAGGTAAATTGATA
CAAGATTCTAATTTGCAAGGTCACCGTATTGGCGGCGTTGAAGTTTCAACCAAACACGCT
GGTTTTATGGTAAATGTAGACAATGGAACTGCTACAGATTATGAAAACCTTATTCATTAT
GTACAAAAGACCGTCAAAGAAAAATTTGGCATTGAATTAAATCGTGAAGTTCGCATTATT
GGTGAACATCCAAAGGAATCGTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SAUSA300_RS03890 [old locus tag: SAUSA300_0722 ]
- symbol: SAUSA300_RS03890
- description: UDP-N-acetylenolpyruvoylglucosamine reductase
- length: 307
- theoretical pI: 5.24718
- theoretical MW: 33797.2
- GRAVY: -0.24202
⊟Function[edit | edit source]
- reaction: EC 1.3.1.98? ExPASyUDP-N-acetylmuramate dehydrogenase UDP-N-acetyl-alpha-D-muramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPHEC 1.1.1.158? ExPASyTransferred entry: 1.3.1.98
- TIGRFAM: Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan UDP-N-acetylenolpyruvoylglucosamine reductase (TIGR00179; EC 1.3.1.98; HMM-score: 240)and 1 moreEnergy metabolism Other glycolate oxidase, subunit GlcD (TIGR00387; HMM-score: 15.7)
- TheSEED: see SAUSA300_0722
- PFAM: no clan defined MurB_C; UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain (PF02873; HMM-score: 103.7)FAD_PCMH (CL0077) FAD_binding_4; FAD binding domain (PF01565; HMM-score: 91.8)and 1 moreno clan defined Stomoxyn; Insect antimicrobial peptide, stomoxyn (PF11585; HMM-score: 13.3)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors: FAD
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.047164
- TAT(Tat/SPI): 0.000865
- LIPO(Sec/SPII): 0.003688
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI: 446531094 NCBI
- RefSeq: WP_000608440 NCBI
- UniProt: see SAUSA300_0722
⊟Protein sequence[edit | edit source]
- MINKDIYQALQQLIPNEKIKVDEPLKRYTYTKTGGNADFYITPTKNEEVQAVVKYAYQNEIPVTYLGNGSNIIIREGGIRGIVISLLSLDHIEVSDDAIIAGSGAAIIDVSRVARDYALTGLEFACGIPGSIGGAVYMNAGAYGGEVKDCIDYALCVNEQGSLIKLTTKELELDYRNSIIQKEHLVVLEAAFTLAPGKMTEIQAKMDDLTERRESKQPLEYPSCGSVFQRPPGHFAGKLIQDSNLQGHRIGGVEVSTKHAGFMVNVDNGTATDYENLIHYVQKTVKEKFGIELNREVRIIGEHPKES
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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