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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus USA300_FPR3757
- locus tag: SAUSA300_RS12405 [old locus tag: SAUSA300_2247 ]
- pan locus tag?: SAUPAN005763000
- symbol: SAUSA300_RS12405
- pan gene symbol?: sarY
- synonym:
- product: transcriptional regulator
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SAUSA300_RS12405 [old locus tag: SAUSA300_2247 ]
- symbol: SAUSA300_RS12405
- product: transcriptional regulator
- replicon: chromosome
- strand: -
- coordinates: 2411865..2412608
- length: 744
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Location: NC_007793 (2411865..2412608) NCBI
- BioCyc: SAUSA300_RS12405 BioCyc
- MicrobesOnline: see SAUSA300_2247
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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721ATGTCTAAATTTAAAGTTAAGCGTTTAACTGCACACATACTAATGTTGAAAGTCATTAAT
GATATGTTGAAATATTCATTTCATCTCACTTTGACTCAAGTGAAACTATTAAATCTATTA
GTTAAATATGATAATTCTGATTCCAATAGCGCTTCAATAGATAGTTTATTAAAAATGAAA
GAAATCCAATCTAAGATGGCCCTTCTTCAAATGTTAAGTTATTTAAACAATCATCAATGG
CTATTGAAAGGAAGAGATCAAAGGGATCAACGTAAATTGACTATTTCGATTAATAAAATG
CATATAGATAAAATAGAATATATGAATAATGAGCTTAGTGACTATATTGAACGTTATTTT
GGTCAATATACATTTGATTTTAGTTGTGACTATGTATCGTATTTATTGTCGTCACAAGAA
TTATTGCGGAATCTAAAGTGTTATTTAAATATGTGTCAATTATCATTAGAAGAGTTATAC
GTTTTAGGAATATTAAATCTGCATAAAGGTCAATTGACGGTTAAAGAATTACAGGGTGAA
TTCCATCACCCGATATTTGCGGTTAGCCCGATTTTAAAGTGTTTAATTTTGAAGGGATTA
GTTAAAAAAGAGAGATGTGAATTAGATGAAAGGCGTGTTATTGTAACAATCAAGCGAGAA
AAGTTTTCTAAAGTCACTATGCTTATTCAAGCATGTTATAATTATCTTGAAAAGGGAATA
CAAGTTAATCTTAATAATAAATAG60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SAUSA300_RS12405 [old locus tag: SAUSA300_2247 ]
- symbol: SAUSA300_RS12405
- description: transcriptional regulator
- length: 247
- theoretical pI: 9.58575
- theoretical MW: 29143.2
- GRAVY: -0.184211
⊟Function[edit | edit source]
- TIGRFAM: Regulatory functions DNA interactions staphylococcal accessory regulator family (TIGR01889; HMM-score: 198.4)and 1 morehomoprotocatechuate degradation operon regulator, HpaR (TIGR02337; HMM-score: 25.4)
- TheSEED: see SAUSA300_2247
- PFAM: HTH (CL0123) MarR_2; MarR family (PF12802; HMM-score: 24.9)MarR; MarR family (PF01047; HMM-score: 20.3)and 2 moreRING (CL0229) zf-C3HC4_5; Zinc finger, C3HC4 type (RING finger) (PF17121; HMM-score: 13.3)HTH (CL0123) TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 12.4)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helices: 0
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.009089
- TAT(Tat/SPI): 0.000213
- LIPO(Sec/SPII): 0.000468
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI: 445955000 NCBI
- RefSeq: WP_000032855 NCBI
- UniProt: see SAUSA300_2247
⊟Protein sequence[edit | edit source]
- MSKFKVKRLTAHILMLKVINDMLKYSFHLTLTQVKLLNLLVKYDNSDSNSASIDSLLKMKEIQSKMALLQMLSYLNNHQWLLKGRDQRDQRKLTISINKMHIDKIEYMNNELSDYIERYFGQYTFDFSCDYVSYLLSSQELLRNLKCYLNMCQLSLEELYVLGILNLHKGQLTVKELQGEFHHPIFAVSPILKCLILKGLVKKERCELDERRVIVTIKREKFSKVTMLIQACYNYLEKGIQVNLNNK
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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