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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus N315
- locus tag: SA_RS01490 [old locus tag: SA0254 ]
- pan locus tag?: SAUPAN001143000
- symbol: SA_RS01490
- pan gene symbol?: bglR
- synonym:
- product: GntR family transcriptional regulator
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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661TTGTTAAAGTATGAACATATTGCTAAGCAACTTAATGCGTTTATACATCAATCTAATTTC
AAACCCGGTGATAAATTGCCAAACGTGACGCAATTAAAAGAACGTTATCAAGTAAGTAAG
AGTACTATCATTAAAGCATTAGGCTTATTGGAACAAGATGGTTTGATCTATCAAGCACAA
GGCAGTGGTATTTATGTGAGAAATATTGCAGATGCCAATCGTATCAACGTCTTTAAGACT
AATGGTTTCTCTAAAAGTTTAGGTGAACATCGAATGACAAGTAAGGTACTTGTTTTTAAG
GAGATGGCAACGCCACCTAAATCTGTACAAGATGAACTCCAATTAAATGCAGATGATACC
GTCTACTATTTAGAGCGATTAAGATTCGTGGACGATGATGTTTTATGTATCGAATATTCT
TATTATCATAAAGAAATCGTGAAATATTTAAATGATGATATTGCTAAGGGCTCTATCTTC
GATTATTTAGAATCAAACATGAAACTTCGTATTGGTTTTTCAGATATTTTCTTTAATGTA
GATAAACTCACTTCAAGTGAAGCTTCATTACTACAATTGTCTACAGGTGAACCATGTTTA
CGTTACCACCAGACTTTTTATACAATGACTGGCAAACCCTTTGATTCGTCTGACATCGTA
TTTCATTATCGTCATGCACAGTTTTATATTCCTAGTAAAAAGTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SA_RS01490 [old locus tag: SA0254 ]
- symbol: SA_RS01490
- description: GntR family transcriptional regulator
- length: 234
- theoretical pI: 8.17816
- theoretical MW: 27058.7
- GRAVY: -0.384188
⊟Function[edit | edit source]
- TIGRFAM: Regulatory functions DNA interactions trehalose operon repressor (TIGR02404; HMM-score: 110.1)Regulatory functions DNA interactions phosphonate utilization transcriptional regulator PhnR (TIGR03337; HMM-score: 88.1)and 10 moreTransport and binding proteins Anions phosphonate metabolism transcriptional regulator PhnF (TIGR02325; HMM-score: 77.3)Regulatory functions DNA interactions phosphonate metabolism transcriptional regulator PhnF (TIGR02325; HMM-score: 77.3)Energy metabolism Amino acids and amines histidine utilization repressor (TIGR02018; HMM-score: 65.6)Regulatory functions DNA interactions histidine utilization repressor (TIGR02018; HMM-score: 65.6)phosphonate utilization associated transcriptional regulator (TIGR03338; HMM-score: 29.1)Fatty acid and phospholipid metabolism Biosynthesis fatty acid metabolism transcriptional regulator FadR (TIGR02812; HMM-score: 16.4)Fatty acid and phospholipid metabolism Degradation fatty acid metabolism transcriptional regulator FadR (TIGR02812; HMM-score: 16.4)Regulatory functions DNA interactions fatty acid metabolism transcriptional regulator FadR (TIGR02812; HMM-score: 16.4)Regulatory functions DNA interactions CRISPR locus-related DNA-binding protein (TIGR01884; HMM-score: 12.3)Unknown function General Rrf2 family protein (TIGR00738; HMM-score: 11.8)
- TheSEED: see SA0254
- PFAM: UTRA (CL0122) UTRA; UTRA domain (PF07702; HMM-score: 90.5)and 11 moreHTH (CL0123) GntR; Bacterial regulatory proteins, gntR family (PF00392; HMM-score: 59.4)HTH_41; Helix-turn-helix domain (PF14502; HMM-score: 21.5)HTH_36; Helix-turn-helix domain (PF13730; HMM-score: 19.2)Rrf2; Transcriptional regulator (PF02082; HMM-score: 16)MarR; MarR family (PF01047; HMM-score: 15.6)HTH_11; HTH domain (PF08279; HMM-score: 14.9)Fe_dep_repress; Iron dependent repressor, N-terminal DNA binding domain (PF01325; HMM-score: 14.5)MarR_2; MarR family (PF12802; HMM-score: 14.2)HTH_27; Winged helix DNA-binding domain (PF13463; HMM-score: 13.6)RPA_C; Replication protein A C terminal (PF08784; HMM-score: 13.2)HTH_DeoR; DeoR-like helix-turn-helix domain (PF08220; HMM-score: 12.5)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
- genes regulated by BglR*, TF important in Beta-glucosides utilization: see SA0254
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.004346
- TAT(Tat/SPI): 0.000275
- LIPO(Sec/SPII): 0.000487
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MLKYEHIAKQLNAFIHQSNFKPGDKLPNVTQLKERYQVSKSTIIKALGLLEQDGLIYQAQGSGIYVRNIADANRINVFKTNGFSKSLGEHRMTSKVLVFKEMATPPKSVQDELQLNADDTVYYLERLRFVDDDVLCIEYSYYHKEIVKYLNDDIAKGSIFDYLESNMKLRIGFSDIFFNVDKLTSSEASLLQLSTGEPCLRYHQTFYTMTGKPFDSSDIVFHYRHAQFYIPSKK
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: BglR* see SA0254
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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