PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA_RS01910 [old locus tag: SA0333 ]
• pan locus tag^?: SAUPAN001884000
• symbol: SA_RS01910
• pan gene symbol^?: fepC
• synonym:
• product: iron permease FTR1 family protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS01910 [old locus tag: SA0333 ]
• symbol: SA_RS01910
• product: iron permease FTR1 family protein
• replicon: chromosome
• strand: +
• coordinates: 391055..392737
• length: 1683
• essential: no DEG other strains

⊟Accession numbers

• Location: NC_002745 (391055..392737) NCBI
• BioCyc: SA_RS01910 BioCyc
• MicrobesOnline: see SA0333

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  1021
  1081
  1141
  1201
  1261
  1321
  1381
  1441
  1501
  1561
  1621
  1681
  
  ATGCTAATAACTGCTGCTATGGTGTGTAGCTTTGGGTTACTGAAAAGTCAGGCAGCAGAA
  CAACAAAGTATTAGTGATGTATATAGTGTGATAACGGATGCGAAATCTGCACTTTCTAAT
  AATTCGATATCGAATGACAATAAGCAGAAAGCAATTGAGCAAGTGGTAAGTGCAGTTAAG
  AAATTATCGCTTGAAGATAATAGTGAAGGTAATGCTGTCAAATCAGATGTGAGAAAGCTT
  GAAGATGCAAAAGCGAATGATAATCAAAAAGATACACTTTCGCAATTAACGAAGTCATTA
  ATTGCTTATGAAGAGAAATTGGCTAGTAAAGATGCGGGTTCTAAAATTAAACTATTGCAA
  CAGCAAGTCGATGCCAAAGATGCTGCGATGACAAAAGCGATTAAAGATAAAAATAAAGCG
  GAATTAGAATCTTTGAACAATAGTTTGAATCAGATTTGGACAAGTAATGAAACAGTGATT
  CGCAATTATGACGCAAATCAATATGGACAAATTGAAGTCGCATTATTACAACTTAGAATT
  GCAATTCATAAGTCACCATTAGATACGGCAAAAGTGTCACATGCTTGGACAACTTTTAAA
  TCAAATATTGATCATGTCGATAAAAAAAGTGATACGTCTGCAAATGATCAATACCATGTA
  TCACAATTAAATGATGCGTTAGAGAAGGCGATTAAAGCTATCGACGACAATCAATTGTCG
  GATGCTGATGCTGCGCTTACACATTTTATAGAAATTTGGCCGTATGTTGAAGGTCAAATT
  CAAACTAAAGACGGGGCTTTGTATACGAAAATTGAAGATAAAATACCATATTATCAAAGT
  GTATTAGACGAACATAATAAATCGCATGTCAAAGATGGTTTAGTAGATATAAACAATCAA
  ATTAAAGAGGTTGTTGGCCATAGTTATAGCTTTGTCGATGTGATGATTATCTTTTTACGT
  GAAGGACTAGAAGTGTTATTAATTGTAATGACATTGACTACCATGACGCGTAAAGTCAAA
  GATAATAAGGGGACTGCAAGTGTGATTGGTGGTGCAATTGCCGGACTTGTACTGAGTATT
  ATCTTAGCAATTACGTTTGTAGAAACTTTAGGGAATAGTGGCATTCTTCGTGAAAGTATG
  GAAGCGGGATTAGGTATCGTTGCGGTCATATTAATGTTTATCGTTGGTGTTTGGATGCAC
  AAACGTTCAAATGCGAAACGCTGGAATGATATGATTAAAAATATGTATGCCAATGCGATT
  AGTAATGGTAATTTGGTATTGTTAGCGACGATTGGTTTAATATCTGTGTTGCGTGAAGGT
  GTTGAGGTTATCATTTTCTATATGGGGATGATAGGTGAGCTAGCGACAAAAGATTTTATT
  ATTGGTATTGCCTTGGCCATAGTGATATTAATTGTCTTTGCGGTATTATTTAGATTTATC
  GTCAGATTGATACCTATATTCTATATATTTAGAGTATTGTCGATCTTTATTTTTATTATG
  GGATTCAAAATGCTTGGCGTAAGTATTCAAAAGTTACAATTATTAGGTGCGATGCCAAGA
  CATGTTATTGAAGGATTCCCAACGATTAACTGGTTGGGCTTCTATCCAAGTTATGAACCA
  TTGATAGCACAAGCTGCTTATATTATGGTAGTTGCTATCTTAATCTTTAAATTTAAAAAA
  TAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  900
  960
  1020
  1080
  1140
  1200
  1260
  1320
  1380
  1440
  1500
  1560
  1620
  1680
  1683
  

⊟Protein

⊟General

• locus tag: SA_RS01910 [old locus tag: SA0333 ]
• symbol: SA_RS01910
• description: iron permease FTR1 family protein
• length: 560
• theoretical pI: 7.3852
• theoretical MW: 62100.9
• GRAVY: 0.187143

⊟Function

• TIGRFAM:
  Unknown function General FTR1 family protein (TIGR00145; HMM-score: 89.4)
• TheSEED: see SA0333
• PFAM:
  MFS (CL0015) FTR1; Iron permease FTR1 family (PF03239; HMM-score: 72.5)
  and 5 more
  no clan defined Tim17; Tim17/Tim22/Tim23/Pmp24 family (PF02466; HMM-score: 15.6)
  MNHE; Na+/H+ ion antiporter subunit (PF01899; HMM-score: 10.4)
  RecG_N; RecG N-terminal helical domain (PF17190; HMM-score: 9.8)
  DUF1539; Domain of Unknown Function (DUF1539) (PF07560; HMM-score: 8.2)
  CCDC84; Coiled coil protein 84 (PF14968; HMM-score: 6.8)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 6
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.469506
  • TAT(Tat/SPI): 0.005896
  • LIPO(Sec/SPII): 0.030291
• predicted transmembrane helices (TMHMM): 6

⊟Accession numbers

• GI: see SA0333
• RefSeq: WP_001822764 NCBI
• UniProt: see SA0333

⊟Protein sequence

• MLITAAMVCSFGLLKSQAAEQQSISDVYSVITDAKSALSNNSISNDNKQKAIEQVVSAVKKLSLEDNSEGNAVKSDVRKLEDAKANDNQKDTLSQLTKSLIAYEEKLASKDAGSKIKLLQQQVDAKDAAMTKAIKDKNKAELESLNNSLNQIWTSNETVIRNYDANQYGQIEVALLQLRIAIHKSPLDTAKVSHAWTTFKSNIDHVDKKSDTSANDQYHVSQLNDALEKAIKAIDDNQLSDADAALTHFIEIWPYVEGQIQTKDGALYTKIEDKIPYYQSVLDEHNKSHVKDGLVDINNQIKEVVGHSYSFVDVMIIFLREGLEVLLIVMTLTTMTRKVKDNKGTASVIGGAIAGLVLSIILAITFVETLGNSGILRESMEAGLGIVAVILMFIVGVWMHKRSNAKRWNDMIKNMYANAISNGNLVLLATIGLISVLREGVEVIIFYMGMIGELATKDFIIGIALAIVILIVFAVLFRFIVRLIPIFYIFRVLSIFIFIMGFKMLGVSIQKLQLLGAMPRHVIEGFPTINWLGFYPSYEPLIAQAAYIMVVAILIFKFKK

⊟Experimental data

• experimentally validated:
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator: Fur* see SA0333

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications