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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS03815 [old locus tag: SA0670 ]
  • pan locus tag?: SAUPAN002601000
  • symbol: SA_RS03815
  • pan gene symbol?: pabC
  • synonym:
  • product: aminodeoxychorismate lyase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS03815 [old locus tag: SA0670 ]
  • symbol: SA_RS03815
  • product: aminodeoxychorismate lyase
  • replicon: chromosome
  • strand: +
  • coordinates: 763100..763708
  • length: 609
  • essential: no DEG other strains

Accession numbers[edit | edit source]

  • Location: NC_002745 (763100..763708) NCBI
  • BioCyc: SA_RS03815 BioCyc
  • MicrobesOnline: see SA0670

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGCAATTATTTGAAACAATGAAAATTGATAATGGACATATCCCTAGACTTACTTATCAT
    ACTAATCGCATAAAATGTTCTTCTGAGCGATTAAACTTTAAATTTGATGAACATGCATGG
    CGAAATGAATTAAACGATGTAACAACAAAGTATCACAGTGGTCAATATAGACTTAAAATC
    GTATTAAATGCTGAAAGCAAATTTGAAACGATAGTGTCACCTTTACCTGAGAAAAGTAGT
    TTTACAGCAAAATTTCAAGTGTTGCCCAAAGTAGTTAATCCAACTTTTATAAAAAATAAA
    ACGACAGAACGAAAGCATTTAGCACACAATCATGAAACAGATTTAATATTGCTAACTTCA
    GAGGACGGCAAGGTCCTTGAATTTGATATTGGCAACATTGTCATTGAAGAGGATGGAAAA
    TGGTACACACCAAGTTATAAAGATGATTTCTTAAAAGGATGCATGCGTGATTATTTAATA
    GATAGTGACAAACTTGTTGAAAAAGACTTTAATAAAAACGAATTGATTTATAAATATCAT
    AACAATGAGATACGTTTATTTTTGATAAATAGTTTACGAGAGGTTGCCGATGTCCACCTT
    TGCCTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    609

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS03815 [old locus tag: SA0670 ]
  • symbol: SA_RS03815
  • description: aminodeoxychorismate lyase
  • length: 202
  • theoretical pI: 7.01683
  • theoretical MW: 23840
  • GRAVY: -0.569802

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Folic acid aminodeoxychorismate lyase (TIGR03461; EC 4.1.3.38; HMM-score: 49.7)
    and 1 more
    Metabolism Amino acid biosynthesis Pyruvate family branched-chain amino acid aminotransferase (TIGR01122; EC 2.6.1.42; HMM-score: 14.3)
  • TheSEED: see SA0670
  • PFAM:
    no clan defined Aminotran_4; Amino-transferase class IV (PF01063; HMM-score: 129.9)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00864
    • TAT(Tat/SPI): 0.00055
    • LIPO(Sec/SPII): 0.004618
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MQLFETMKIDNGHIPRLTYHTNRIKCSSERLNFKFDEHAWRNELNDVTTKYHSGQYRLKIVLNAESKFETIVSPLPEKSSFTAKFQVLPKVVNPTFIKNKTTERKHLAHNHETDLILLTSEDGKVLEFDIGNIVIEEDGKWYTPSYKDDFLKGCMRDYLIDSDKLVEKDFNKNELIYKYHNNEIRLFLINSLREVADVHLCL

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]