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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS04745 [old locus tag: SA0836 ]
  • pan locus tag?: SAUPAN003114000
  • symbol: SA_RS04745
  • pan gene symbol?: —
  • synonym:
  • product: LysR family transcriptional regulator

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS04745 [old locus tag: SA0836 ]
  • symbol: SA_RS04745
  • product: LysR family transcriptional regulator
  • replicon: chromosome
  • strand: -
  • coordinates: 949312..950181
  • length: 870
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (949312..950181) NCBI
  • BioCyc: SA_RS04745 BioCyc
  • MicrobesOnline: see SA0836

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGAATTTGGATTGGTACTATACATTTGTCATTTTAGCGAAGACGTTAAACTATCGATTA
    GCTAGTGAAGAAATTAATCTCACTATACCTTCTATACATAAGCAAATTAAAAATTTAGAA
    CAGCATCTCAATGTGAAACTATTTGAAACTTATAAAAATCAAATTATCTTGACTGAAGAT
    GGTCATACATTTCTTCCAATTGCGCAAAGTTTTATTGAACAATATGAAAGTGGCATCAAA
    CATATCCAACTTAAAAAAACGATGTTTCAATCGAAATTAAATGTTGTCGTGTCTTCATAT
    ATCGCGACATTCATTATGCCCAAATTTTTAAAATCTTTCTTTAACGAGCATCCGTTTATC
    GATGTTTCTCTCCATGTCAAAAATGAAAATATTGAAAAAGATATTAATAATCATACGTAT
    GACATCGGGATTAGCAGAAATCAACCTAAACTAAGAGAAGTTCATTCTGAAAAAGTATGC
    GAAGGTAAAATTGTATTGATTGCTCCCAATAAAGAGAATAATCATCTTCTAACTGAGGCA
    TCTTTATTTGAAAAATACAAAATAATAAGTGATAACCATCCAGAATATTGGTCATCACTT
    AAAAATAATATTTTAAATATTTATGGAAAAGCACAATTTCTATCTATCAATGATGTGCAT
    ACTTCAATTAAATTAATCGAAATGAATCAAGGTATATCATTCCTGCCTATTTATATAACA
    ACAGATAGTGATTACAATATTTCGGTTATTAACACGAAAATTTTACAAGCGCCTATTTCA
    TTTACATATATATACAGCAAAAAAGAAAGCCCAGAAATATTGGTTTTTATTAAATCATTT
    AAAAAGTATATTGCCAATGAACAATTATAA
    60
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    870

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS04745 [old locus tag: SA0836 ]
  • symbol: SA_RS04745
  • description: LysR family transcriptional regulator
  • length: 289
  • theoretical pI: 8.35837
  • theoretical MW: 33727.6
  • GRAVY: -0.216263

⊟Function[edit | edit source]

  • TIGRFAM:
    Signal transduction Regulatory functions DNA interactions aminoethylphosphonate catabolism associated LysR family transcriptional regulator (TIGR03339; HMM-score: 64.5)
    putative choline sulfate-utilization transcription factor (TIGR03418; HMM-score: 52.1)
    and 6 more
    Metabolism Energy metabolism Other pca operon transcription factor PcaQ (TIGR02424; HMM-score: 49.5)
    Signal transduction Regulatory functions DNA interactions pca operon transcription factor PcaQ (TIGR02424; HMM-score: 49.5)
    Signal transduction Regulatory functions DNA interactions D-serine deaminase transcriptional activator (TIGR02036; HMM-score: 48)
    Cellular processes Cellular processes Toxin production and resistance transcriptional regulator, ArgP family (TIGR03298; HMM-score: 11.2)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair transcriptional regulator, ArgP family (TIGR03298; HMM-score: 11.2)
    Signal transduction Regulatory functions DNA interactions transcriptional regulator, ArgP family (TIGR03298; HMM-score: 11.2)
  • TheSEED: see SA0836
  • PFAM:
    PBP (CL0177) LysR_substrate; LysR substrate binding domain (PF03466; HMM-score: 79.6)
    and 2 more
    HTH (CL0123) HTH_1; Bacterial regulatory helix-turn-helix protein, lysR family (PF00126; HMM-score: 43.7)
    SUKH (CL0526) SUKH_6; SMI1-KNR4 cell-wall (PF14568; HMM-score: 12.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.67
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 0.15
    • Extracellular Score: 0.17
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.014918
    • TAT(Tat/SPI): 0.000286
    • LIPO(Sec/SPII): 0.001636
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNLDWYYTFVILAKTLNYRLASEEINLTIPSIHKQIKNLEQHLNVKLFETYKNQIILTEDGHTFLPIAQSFIEQYESGIKHIQLKKTMFQSKLNVVVSSYIATFIMPKFLKSFFNEHPFIDVSLHVKNENIEKDINNHTYDIGISRNQPKLREVHSEKVCEGKIVLIAPNKENNHLLTEASLFEKYKIISDNHPEYWSSLKNNILNIYGKAQFLSINDVHTSIKLIEMNQGISFLPIYITTDSDYNISVINTKILQAPISFTYIYSKKESPEILVFIKSFKKYIANEQL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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