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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS05450 [old locus tag: SA0962 ]
  • pan locus tag?: SAUPAN003340000
  • symbol: SA_RS05450
  • pan gene symbol?: ftsW
  • synonym:
  • product: cell division protein FtsW

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS05450 [old locus tag: SA0962 ]
  • symbol: SA_RS05450
  • product: cell division protein FtsW
  • replicon: chromosome
  • strand: +
  • coordinates: 1089462..1090688
  • length: 1227
  • essential: no DEG other strains

Accession numbers[edit | edit source]

  • Location: NC_002745 (1089462..1090688) NCBI
  • BioCyc: SA_RS05450 BioCyc
  • MicrobesOnline: see SA0962

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGAAGAATTTTAGAAGTATTTTACGGTATATTGGTAAAACCTCAAAGTTTATTGATTAT
    CCGTTATTAGTTACATATATTGTATTGAGTTTAATTGGATTAGTGATGGTATATAGTGCA
    AGTATGGTTCCAGCAACTAAAGGCACATTGACTGGTGGTATCGATGTTCCAGGAACGTAT
    TTTTACAACCGACAATTAGCATATGTCATAATGAGTTTTATAATTGTATTTTTTATTGCA
    TTTTTAATGAATGTTAAATTACTGAGTAATATTAAAGTGCAAAAAGGTATGATTATAACT
    ATCGTCTCACTATTATTACTGACGTTAGTAATAGGTAAAGATATTAATGGTTCTAAAAGT
    TGGATAAACTTAGGATTTATGAATTTACAGGCATCTGAGTTATTAAAAATTGCAATCATA
    TTATATATCCCATTTATGATCAGTAAAAAAATGCCTAGAGTATTAAGTAAACCAAAATTA
    ATTTTAAGTCCTATTGTATTAGCATTAGGTTGTACGTTTTTAGTTTTCTTACAAAAAGAC
    GTAGGGCAAACATTACTAATATTAATTATTTTAGTTGCGATTATTTTTTATTCAGGAATT
    GGGGTAAACAAAGTCCTAAGATTTGGTATACCAGCAGTGCTAGGATTCTTAGTAGTATTT
    GTCATTGCATTAATGGCTGGTTGGTTACCAAGCTATTTAACTGCCAGATTTAGTACGCTA
    ACAGATCCATTCCAATTCGAATCAGGAACTGGATACCATATTTCCAATTCATTGCTTGCG
    ATAGGTAACGGTGGCGTATTTGGAAAAGGATTAGGAAATAGTGCAATGAAATTGGGCTAT
    TTACCAGAACCACATACAGATTTTATTTTTGCAATTATTTGCGAAGAATTAGGTTTAATC
    GGAGGATTGCTAGTTATTACTTTAGAGTTCTTTATTGTATATCGTGCCTTCCAGTTTGCA
    AATAAAACATCATCATATTTTTATAAACTTGTGTGTGTTGGGATTGCCACATACTTTGGA
    AGTCAAACGTTTGTAAACATTGGCGGTATTTCGGCAACAATTCCATTAACTGGTGTGCCA
    TTGCCATTTATCAGCTTTGGTGGATCATCAATGATTAGTTTAAGTATTGCTATGGGATTA
    CTTCTGATTGTAGGTAAACAAATCAAAGTAGACCAGCAACGAAAGAAACAACAACAAAAA
    GTTGATATAAGAAGACAATTTAATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1227

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS05450 [old locus tag: SA0962 ]
  • symbol: SA_RS05450
  • description: cell division protein FtsW
  • length: 408
  • theoretical pI: 10.3601
  • theoretical MW: 44881.8
  • GRAVY: 0.8125

Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan cell division protein FtsW (TIGR02614; HMM-score: 292.7)
    Cellular processes Cellular processes Cell division cell division protein FtsW (TIGR02614; HMM-score: 292.7)
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan rod shape-determining protein RodA (TIGR02210; HMM-score: 268.2)
    Cellular processes Cellular processes Cell division rod shape-determining protein RodA (TIGR02210; HMM-score: 268.2)
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan stage V sporulation protein E (TIGR02615; HMM-score: 234.3)
    Cellular processes Cellular processes Sporulation and germination stage V sporulation protein E (TIGR02615; HMM-score: 234.3)
  • TheSEED: see SA0962
  • PFAM:
    Membrane_trans (CL0142) FTSW_RODA_SPOVE; Cell cycle protein (PF01098; HMM-score: 303.3)
    and 1 more
    no clan defined IncA; IncA protein (PF04156; HMM-score: 12)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 10
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.340562
    • TAT(Tat/SPI): 0.003618
    • LIPO(Sec/SPII): 0.013271
  • predicted transmembrane helices (TMHMM): 10

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MKNFRSILRYIGKTSKFIDYPLLVTYIVLSLIGLVMVYSASMVPATKGTLTGGIDVPGTYFYNRQLAYVIMSFIIVFFIAFLMNVKLLSNIKVQKGMIITIVSLLLLTLVIGKDINGSKSWINLGFMNLQASELLKIAIILYIPFMISKKMPRVLSKPKLILSPIVLALGCTFLVFLQKDVGQTLLILIILVAIIFYSGIGVNKVLRFGIPAVLGFLVVFVIALMAGWLPSYLTARFSTLTDPFQFESGTGYHISNSLLAIGNGGVFGKGLGNSAMKLGYLPEPHTDFIFAIICEELGLIGGLLVITLEFFIVYRAFQFANKTSSYFYKLVCVGIATYFGSQTFVNIGGISATIPLTGVPLPFISFGGSSMISLSIAMGLLLIVGKQIKVDQQRKKQQQKVDIRRQFN

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]