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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS08845 [old locus tag: SA1568 ]
  • pan locus tag?: SAUPAN004414000
  • symbol: SA_RS08845
  • pan gene symbol?: —
  • synonym:
  • product: MBL fold metallo-hydrolase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS08845 [old locus tag: SA1568 ]
  • symbol: SA_RS08845
  • product: MBL fold metallo-hydrolase
  • replicon: chromosome
  • strand: -
  • coordinates: 1798244..1799086
  • length: 843
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (1798244..1799086) NCBI
  • BioCyc: SA_RS08845 BioCyc
  • MicrobesOnline: see SA1568

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGAAGATCGGGGATATATCTATTCATTATCTAAATGGTGGCAATACAAAAATGGATGGC
    GGTGCAATGTTTGGTGTTGTTCCGAAGCCGTTGTGGTCAAAGCAATACAATGCAAATGAA
    CGAAATCAAATCAATTTACCGACACATCCAATTTTGATTCAAACGGCTCAATATAATTTG
    ATTATAGATGCGGGTATTGGTAATGGTAAATTATCTGAAAAGCAATTACGTAATTTTGGA
    GTAGATGAAGAAAGTCATATAATTGCTGATTTGGCAAATTATAATTTAACGCCAAAGGAT
    ATTGATTATGTGCTAATGACACATATGCATTTTGATCATGCTGCCGGTTTGACTGATCAA
    GCGGGACATGCAATTTTTGAAAATGCGATTCATGTTGTGCAACAAGATGAGTGGCATGAG
    TTTATTGCACCTAATATAAGAAGTAAATCAACTTACTGGGATAAGAATAAAGGCGATTAT
    AGTAACAAGTTGATTTTATTCGAAAAACATTTTGAACCGGTTCCGGGTATCAAGATGCAA
    CATAGTGGAGGTCATAGCTTTGGCCACACGATTATTACGATTGAAAGTCAAGGAGATAAA
    GCAGTTCATATGGGTGATATATTCCCAACTACTGCACATAAAAATCCTCTATGGGTAACG
    GCATATGATGATTATCCTATGCAATCGATTCGTGAAAAAGAACGCATGATACCATATTTT
    ATTCAGCAACAATATTGGTTCTTGTTTTATCATGATGAAAACTACTTTGCTGTAAAATAC
    AGCGATGATGGTGAAAACATAGATGCATATATTTTACGTGAAACATTAGTTGATAATAAC
    TAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    843

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS08845 [old locus tag: SA1568 ]
  • symbol: SA_RS08845
  • description: MBL fold metallo-hydrolase
  • length: 280
  • theoretical pI: 5.93292
  • theoretical MW: 32173.9
  • GRAVY: -0.510714

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Transcription RNA processing ribonuclease Z (TIGR02651; EC 3.1.26.11; HMM-score: 19.9)
    Unknown function Enzymes of unknown specificity quinoprotein relay system zinc metallohydrolase 2 (TIGR04559; EC 3.-.-.-; HMM-score: 17)
    and 2 more
    phosphonate metabolism protein PhnP (TIGR03307; HMM-score: 12.8)
    arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein (TIGR03675; HMM-score: 12.8)
  • TheSEED: see SA1568
  • PFAM:
    Metallo-HOrase (CL0381) Lactamase_B; Metallo-beta-lactamase superfamily (PF00753; HMM-score: 55.9)
    and 2 more
    Lactamase_B_3; Beta-lactamase superfamily domain (PF13483; HMM-score: 22.6)
    Lactamase_B_2; Beta-lactamase superfamily domain (PF12706; HMM-score: 22.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.027381
    • TAT(Tat/SPI): 0.000388
    • LIPO(Sec/SPII): 0.00277
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKIGDISIHYLNGGNTKMDGGAMFGVVPKPLWSKQYNANERNQINLPTHPILIQTAQYNLIIDAGIGNGKLSEKQLRNFGVDEESHIIADLANYNLTPKDIDYVLMTHMHFDHAAGLTDQAGHAIFENAIHVVQQDEWHEFIAPNIRSKSTYWDKNKGDYSNKLILFEKHFEPVPGIKMQHSGGHSFGHTIITIESQGDKAVHMGDIFPTTAHKNPLWVTAYDDYPMQSIREKERMIPYFIQQQYWFLFYHDENYFAVKYSDDGENIDAYILRETLVDNN

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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