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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus N315
- locus tag: SA_RS09080 [old locus tag: SA1614 ]
- pan locus tag?: SAUPAN004510000
- symbol: SA_RS09080
- pan gene symbol?: menC
- synonym:
- product: o-succinylbenzoate synthase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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961ATGAAGTTGACAGCTTTGCATTTTTATAAATATAGTGAGCCATTTAAGTCACAAATTGTA
ACACCGAAAGTCACTTTAACGCATCGTGATTGTTTGTTTATCGAATTGATTGATGACAAA
GGAAATGCATATTTCGGGGAATGTAACGCTTTTCAAACAGATTGGTATGATCATGAAACA
ATTGCTTCAGTGAAACATGTAATTGAGCAATGGTTCGAAGATAATAGAAATAAATCATTT
GAAACGTATGAAGCAGCACTAAAATTAGTAGATTCATTGGAAAATACGCCTGCTGCAAGG
GCAACTATTGTCATGGCATTGTATCAAATGTTTCATGTACTGCCTTCATTTTCAGTAGCA
TATGGAGCGACAGCGAGCGGCTTATCAAATAAACAACTAGAGTCATTGAAAGCAACAAAG
CCGACCAGAATTAAATTAAAATGGACGCCTCAAATCATGCATCAAATTAGAGTGTTACGG
GAATTAGACTTTCACTTTCAATTGGTTATAGATGCAAATGAGTCATTGGATCGTCAAGAT
TTCACACAGTTACAGCTATTAGCGCGTGAACAGGTTCTTTATATCGAAGAGCCATTTAAA
GATATCTCCATGCTTGATGAAGTAGTGGATGGAACAATACCTCCAATAGCCCTTGATGAA
AAGGCAACATCGTTGTTGGACATAATTAATTTGATAGAATTATACAATGTGAAAGTTGTT
GTATTAAAACCATTTCGTCTAGGTGGCATTGATAAAGTGCAAACGGCAATTGATACTTTG
AAAAGTCATGGTGTAAAAGTGGTTATTGGCGGCATGTACGAATATGGTTTAAGCCGTTAT
TTTACAGCGATGCTTGCTCGTAAAGGTGATTATCCAGGAGATGTTACACCAGCAGGTTAT
TATTTTGATCAAGATGTGGTTACTAAATCAGGCATATTAAAAGAGGGGCGACTCGAATTT
CGCCCCCCTTTAGTGGATATAACTCAATTACAACCATATTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SA_RS09080 [old locus tag: SA1614 ]
- symbol: SA_RS09080
- description: o-succinylbenzoate synthase
- length: 333
- theoretical pI: 5.64797
- theoretical MW: 38030.5
- GRAVY: -0.142042
⊟Function[edit | edit source]
- reaction: EC 4.2.1.113? ExPASyo-succinylbenzoate synthase (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate = 2-succinylbenzoate + H2O
- TIGRFAM: Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone o-succinylbenzoate synthase (TIGR01928; EC 4.2.1.113; HMM-score: 441.3)and 4 moreBiosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone o-succinylbenzoate synthase (TIGR01927; EC 4.2.1.113; HMM-score: 83.2)muconate and chloromuconate cycloisomerases (TIGR02534; EC 5.5.1.-; HMM-score: 28.7)Regulatory functions DNA interactions CRISPR locus-related DNA-binding protein (TIGR01884; HMM-score: 12.2)Amino acid biosynthesis Aspartate family S-methyl-5-thioribose-1-phosphate isomerase (TIGR00512; EC 5.3.1.23; HMM-score: 11.9)
- TheSEED: see SA1614
- PFAM: Enolase_TIM (CL0256) MR_MLE_C; Enolase C-terminal domain-like (PF13378; HMM-score: 55.7)and 1 moreMAAL_C; Methylaspartate ammonia-lyase C-terminus (PF07476; HMM-score: 14.2)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors: a divalent metal cation
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.004548
- TAT(Tat/SPI): 0.000118
- LIPO(Sec/SPII): 0.000575
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MKLTALHFYKYSEPFKSQIVTPKVTLTHRDCLFIELIDDKGNAYFGECNAFQTDWYDHETIASVKHVIEQWFEDNRNKSFETYEAALKLVDSLENTPAARATIVMALYQMFHVLPSFSVAYGATASGLSNKQLESLKATKPTRIKLKWTPQIMHQIRVLRELDFHFQLVIDANESLDRQDFTQLQLLAREQVLYIEEPFKDISMLDEVVDGTIPPIALDEKATSLLDIINLIELYNVKVVVLKPFRLGGIDKVQTAIDTLKSHGVKVVIGGMYEYGLSRYFTAMLARKGDYPGDVTPAGYYFDQDVVTKSGILKEGRLEFRPPLVDITQLQPY
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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