From AureoWiki
Jump to navigation Jump to search

NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS11460 [old locus tag: SA1990 ]
  • pan locus tag?: SAUPAN005584000
  • symbol: SA_RS11460
  • pan gene symbol?:
  • synonym:
  • product: alpha/beta hydrolase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS11460 [old locus tag: SA1990 ]
  • symbol: SA_RS11460
  • product: alpha/beta hydrolase
  • replicon: chromosome
  • strand: -
  • coordinates: 2261522..2262406
  • length: 885
  • essential: no DEG other strains

Accession numbers[edit | edit source]

  • Location: NC_002745 (2261522..2262406) NCBI
  • BioCyc: SA_RS11460 BioCyc
  • MicrobesOnline: see SA1990

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGGGAGTTAAAAGTGTGAAGAAAATTTTTGTAATTATTACGACATTGTTAGCGGTCGCT
    ATTATTATAGGCTCTATTATTACGGTGGTGTTTAGTCAACGACAGGCACAAACATTTAAA
    ATACAACAACAGCAATTTGTTAAAAAGCCAATTCCAACATTGTTCTTACATGGATTTGGT
    GGTAGTGCCAATTCTGAAAAGTTTATGGTGAAGCAAGCAGAAAAAAGAGGGGTAACTAAA
    GATATCATCACTGCTTACGTTTCAAAGGATGGTGCAGTGACATTTAAAGGGAAACTAAGA
    AAAGATGCAGTGAATCCTATTGTGAAAATTGAACTTGAAAATAACAGACAAGGCTATTTG
    GATAAGAATGCTGCGTGGTTTAAAAATGTACTGACTAAGTTACAATCTGAATACAATTTC
    GATAAATTCAACTTTGTCGGTCACTCAATGGGGAACTTAACATTTGCACAATATATGATG
    ACATATGGTAACGACAAGTCACTGCCACAGTTAAACAAACAAGTGAATATTGCAGGGACA
    TTTAATGGTGTTTTAAATATGAATGAAGATGTCAATGAAATTACAGTTGATAAAGATGGT
    AAACCAAGTCGAATGAATCAACCTTATCAGCAATTACGCGTGCTAAAAGATATTTATAAA
    GGTAAAGGTATCGAAGTGCTAAATATTTATGGAGATTTGAAAGATGGTACACATTCAGAC
    GGCAGAGTGTCTAATAGTTCTTCGAAATCATTAAAATATTTACTGGGAAATAGTCCGAAA
    AGTTATCGAGAATCTAAATATGAAGGTGAGCCTGCACAACATAGTCAGCTTCATGAGAAT
    GAAAATGTTGCTAATGAGTTAATCGACTTCTTATGGAAAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    885

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS11460 [old locus tag: SA1990 ]
  • symbol: SA_RS11460
  • description: alpha/beta hydrolase
  • length: 294
  • theoretical pI: 10.1578
  • theoretical MW: 33155.8
  • GRAVY: -0.446259

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: see SA1990
  • PFAM:
    AB_hydrolase (CL0028) DUF915; Alpha/beta hydrolase of unknown function (DUF915) (PF06028; HMM-score: 344.1)
    and 5 more
    Abhydrolase_1; alpha/beta hydrolase fold (PF00561; HMM-score: 16.1)
    DUF676; Putative serine esterase (DUF676) (PF05057; HMM-score: 15.7)
    DUF900; Alpha/beta hydrolase of unknown function (DUF900) (PF05990; HMM-score: 12.1)
    Hydrolase_4; Serine aminopeptidase, S33 (PF12146; HMM-score: 11.7)
    no clan defined DAG1; Dystroglycan (Dystrophin-associated glycoprotein 1) (PF05454; HMM-score: 11.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.390072
    • TAT(Tat/SPI): 0.002259
    • LIPO(Sec/SPII): 0.027738
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MGVKSVKKIFVIITTLLAVAIIIGSIITVVFSQRQAQTFKIQQQQFVKKPIPTLFLHGFGGSANSEKFMVKQAEKRGVTKDIITAYVSKDGAVTFKGKLRKDAVNPIVKIELENNRQGYLDKNAAWFKNVLTKLQSEYNFDKFNFVGHSMGNLTFAQYMMTYGNDKSLPQLNKQVNIAGTFNGVLNMNEDVNEITVDKDGKPSRMNQPYQQLRVLKDIYKGKGIEVLNIYGDLKDGTHSDGRVSNSSSKSLKYLLGNSPKSYRESKYEGEPAQHSQLHENENVANELIDFLWKK

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]