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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS12015 [old locus tag: SA2091 ]
  • pan locus tag?: SAUPAN005763000
  • symbol: SA_RS12015
  • pan gene symbol?: sarY
  • synonym:
  • product: transcriptional regulator

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS12015 [old locus tag: SA2091 ]
  • symbol: SA_RS12015
  • product: transcriptional regulator
  • replicon: chromosome
  • strand: -
  • coordinates: 2349262..2350005
  • length: 744
  • essential: no DEG other strains

Accession numbers[edit | edit source]

  • Location: NC_002745 (2349262..2350005) NCBI
  • BioCyc: SA_RS12015 BioCyc
  • MicrobesOnline: see SA2091

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGTCTAAATTTAAAGTTAAGCGTTTAACTGCACACATACTAATGTTGAAAGTCATTAAT
    GATATGTTGAAATATTCATTTCATCTCACTTTGACTCAAGTGAAACTATTAAATCTATTA
    GTTAAATATGATAATTCTGATTCCAATAGCGCTTCAATAGATAGGTTATTAAAAATGAAA
    GAAATCCAATCTAAGATGGCACTTCTTCAAATGTTAAGTTATTTAAACAATCATCAATGG
    CTATTGAAAGGAAGAGATCAAAGGGATCAACGTAAATTGACTATTTCGATTAATAAAATG
    CATATAGATAAAATAGAATATATGAATAATGAGCTTAGTGACTATATTGAACGTTATTTT
    GGTCAATATACATTTGATTTTAGTTGTGACTATGTATCGTATTTATTGTCGTCACAAGAA
    TTATTTCGAAATCTAAAGTGTTATTTAAATATGTGTCAATTAACATTAGAAGAGTTATAC
    GTTTTAGGAATATTAAATCTGCATAAAGGTCAATTGACGGTTAAAGAATTACAGGGTGAA
    TTCCATCACCCGATATTTGCGGTTAGCCCGATTTTAAAGTGTTTAATTTTGAAGGGATTA
    GTTAAAAAAGAGAGATGTGAATTAGATGAAAGACGTGTTATTGTAACAATCAAGCGAGAA
    AAGTTTTCTAAAGTCACTATGCTTATTCAAGCATGTTATAATTATCTTGAAAAGGGAATA
    CAAGTTAAGCTTAATAATAAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    744

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS12015 [old locus tag: SA2091 ]
  • symbol: SA_RS12015
  • description: transcriptional regulator
  • length: 247
  • theoretical pI: 9.76215
  • theoretical MW: 29274.5
  • GRAVY: -0.204453

Function[edit | edit source]

  • TIGRFAM:
    Signal transduction Regulatory functions DNA interactions staphylococcal accessory regulator family (TIGR01889; HMM-score: 199.3)
    and 1 more
    homoprotocatechuate degradation operon regulator, HpaR (TIGR02337; HMM-score: 27.7)
  • TheSEED: see SA2091
  • PFAM:
    HTH (CL0123) MarR_2; MarR family (PF12802; HMM-score: 26.6)
    and 1 more
    MarR; MarR family (PF01047; HMM-score: 20.8)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.008448
    • TAT(Tat/SPI): 0.000213
    • LIPO(Sec/SPII): 0.00045
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MSKFKVKRLTAHILMLKVINDMLKYSFHLTLTQVKLLNLLVKYDNSDSNSASIDRLLKMKEIQSKMALLQMLSYLNNHQWLLKGRDQRDQRKLTISINKMHIDKIEYMNNELSDYIERYFGQYTFDFSCDYVSYLLSSQELFRNLKCYLNMCQLTLEELYVLGILNLHKGQLTVKELQGEFHHPIFAVSPILKCLILKGLVKKERCELDERRVIVTIKREKFSKVTMLIQACYNYLEKGIQVKLNNK

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]