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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS12170 [old locus tag: SA2117 ]
  • pan locus tag?: SAUPAN005807000
  • symbol: SA_RS12170
  • pan gene symbol?:
  • synonym:
  • product: sodium:proton antiporter

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS12170 [old locus tag: SA2117 ]
  • symbol: SA_RS12170
  • product: sodium:proton antiporter
  • replicon: chromosome
  • strand: -
  • coordinates: 2380160..2381473
  • length: 1314
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_002745 (2380160..2381473) NCBI
  • BioCyc: G1G21-2467 BioCyc
  • MicrobesOnline:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGGAAGTACATAAAAAGAGCAATGCTTGGGCATTATTCCCCTTGTTATTATTTGTGGCG
    TTGTTTTTAGGCGTAGGTATTATCACAGGTGATTTTACTTCAATGCCATTAAATGTTGCA
    ATTACGATAACGGTAATTGTGGCGTTATTAATGAATCGAAAAGAATCATTTGCTAAAAAA
    GTTGAGGTCTTCACGAAAGGTGCAGGCCATTCAAACATTATTTTAATGATGTTGATTTTT
    ATTTTAGCAGGTGCATTTTCAAATACAGCTGAAAAAATGGGTGGCGTAAAGTCGACAGTT
    AATTTAGGACTATCATTAATCCCAGAAAATTTAATTATTGTAGGATTGTTTGTGATTTGT
    ATGTTTGTTTCTATATCTATGGGGACGTCTGTAGGAACTGTTGCTGCAATAGCACCTGTT
    GGTTACGGATTTGCACAAGCGACAGATGTACCAACTGCGCTAGCAATGGCTACAGTTGTT
    GGAGGTGCAATGTTCGGCGATAATCTATCAATGATTTCAGATACAACAATTGCTGCGGTT
    AGAACACAACATACGAAAATGAAAGATAAATTCAGAGTAAACTTTAAAATTGTATTGCCA
    GGTGCTATTTTAACGATTATTATTCTGTATTTCTTAACGAATGGCATTTCTTTAAATCAT
    GCTAAAAACTATGATTATAATCTAATTAAAGTTGTACCGTATATTTTAGTATTGGTATTA
    GCATTATTAGGTGTAAATGTCATTATCGTATTGATTGGCGGAACATTATTAGCTGGAATC
    ATTGGTCTCATAGATGGTTCATTCGGTTGGATGGGACTACTAGATGCAGTGTCCAAAGGT
    ATTATAAGCATGGAAGATATTGCTATGATTGCGTTGCTAATTGGTGGTTTAGTCGGTATT
    ATTCAACACAATGGTGGTATTGAATGGTTGTTGCAATTTGTTCGCTCTAAAGTGAAATCA
    AAGCGTGGCGCAGAATTAGGAATTGCGAGTTTGGTAAGTGTCGCAGATATTGCCACGGCA
    AACAACACCATCTCTATTATTATGTCAGGTCCTTTAGCTAAAAATATTGCAGATGAATAT
    GATGTAGATTCAAGGAAATCAGCAAGTATTCTTGATATATTTGGAGGCTGCTTCCAAGGT
    TTATTACCATATAGCCCGCAAGTCATTTCAGCGGCTGGTGTAGCTGGTATTTCACCATTA
    ATGTTATTCCCATACAGCATTTATCCTATATTATTAGGTGTATGCGGACTTATTGCGATT
    TTATTTAATTTTCCAAAGCTAAAAAAGAACACTAGTCAAGAAATGAAACATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1314

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS12170 [old locus tag: SA2117 ]
  • symbol: SA_RS12170
  • description: sodium:proton antiporter
  • length: 437
  • theoretical pI: 9.40995
  • theoretical MW: 46338.2
  • GRAVY: 0.849199

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Cations and iron carrying compounds Na+/H+ antiporter NhaC (TIGR00931; HMM-score: 87.8)
  • TheSEED:
  • PFAM:
    IT (CL0182) Na_H_antiporter; Na+/H+ antiporter family (PF03553; HMM-score: 79.3)
    and 3 more
    Na_H_antiport_2; Na+-H+ antiporter family (PF13726; HMM-score: 21.2)
    CitMHS; Citrate transporter (PF03600; HMM-score: 18.7)
    DcuC; C4-dicarboxylate anaerobic carrier (PF03606; HMM-score: 13.9)

Structure, modifications & interactions[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 10
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.099348
    • TAT(Tat/SPI): 0.000884
    • LIPO(Sec/SPII): 0.067644
  • predicted transmembrane helices (TMHMM): 10

Accession numbers[edit | edit source]

  • GI: 446373973 NCBI
  • RefSeq: WP_000451828 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MEVHKKSNAWALFPLLLFVALFLGVGIITGDFTSMPLNVAITITVIVALLMNRKESFAKKVEVFTKGAGHSNIILMMLIFILAGAFSNTAEKMGGVKSTVNLGLSLIPENLIIVGLFVICMFVSISMGTSVGTVAAIAPVGYGFAQATDVPTALAMATVVGGAMFGDNLSMISDTTIAAVRTQHTKMKDKFRVNFKIVLPGAILTIIILYFLTNGISLNHAKNYDYNLIKVVPYILVLVLALLGVNVIIVLIGGTLLAGIIGLIDGSFGWMGLLDAVSKGIISMEDIAMIALLIGGLVGIIQHNGGIEWLLQFVRSKVKSKRGAELGIASLVSVADIATANNTISIIMSGPLAKNIADEYDVDSRKSASILDIFGGCFQGLLPYSPQVISAAGVAGISPLMLFPYSIYPILLGVCGLIAILFNFPKLKKNTSQEMKH

Experimental data[edit | edit source]

  • experimentally validated: no data available

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]