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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS12215 [old locus tag: SA2126 ]
  • pan locus tag?: SAUPAN005823000
  • symbol: SA_RS12215
  • pan gene symbol?: lyrA
  • synonym:
  • product: lysostaphin resistance protein A

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS12215 [old locus tag: SA2126 ]
  • symbol: SA_RS12215
  • product: lysostaphin resistance protein A
  • replicon: chromosome
  • strand: +
  • coordinates: 2391228..2392487
  • length: 1260
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (2391228..2392487) NCBI
  • BioCyc: SA_RS12215 BioCyc
  • MicrobesOnline: see SA2126

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGAAGAACAATAAAATTTCTGGTTTTCAATGGGCAATGACGATTTTCGTCTTCTTTGTC
    ATTACAATGGCGTTATCCATTATGCTCAGAGATTTCCAGTCTATAATTGGTGTCAAACAC
    TTTATATTTGAAGTTACAGATCTAGCACCATTAATTGCTGCAATCATTTGTATACTCGTT
    TTCAAATATAAAAAGGTCCAACTTGCAGGTTTAAAATTCTCAATCAGCCTGAAAGTAATT
    GAACGTCTATTGCTAGCTTTAATTTTACCTTTAATTATTCTAATTATTGGTATGTACAGC
    TTTAATACATTTGCAGATAGCTTTATTTTATTACAATCAACAGGCTTATCAGTACCTATT
    ACACACATTCTGATTGGACATATTCTGATGGCGTTCGTAGTAGAATTCGGATTCCGTTCA
    TACTTACAAAATATTGTTGAAACGAAAATGAACACGTTCTTTGCAAGTATTGTTGTTGGT
    TTGATGTATTCAGTTTTCTCAGCAAATACAACTTATGGTACAGAATTTGCTGCTTATAAC
    TTCCTTTATACATTCTCATTCTCTATGATTCTTGGTGAATTAATTAGAGCGACTAAAGGA
    CGTACAATTTATATTGCAACGACATTCCATGCTTCAATGACATTCGGACTTATTTTCTTG
    TTTAGCGAAGAAATCGGCGATCTATTTTCAATCAAAGTCATCGCCATTTCAACAGCAATC
    GTTGCAGTAGGATACATTGGTTTAAGCTTAATTATCCGAGGTATTGCATATTTAACAACA
    AGACGAAACCTTGAAGAACTTGAGCCTAATAATTATTTAGACCATGTCAATGACGATGAA
    GAAACTAATCATACTGAGGCTGAAAAATCTTCTTCAAATATTAAAGATGCTGAAAAAACA
    GGTGTAGCTACTGCATCAACGGTTGGTGTTGCTAAAAATGATACTGAAAATACAGTGGCT
    GACGAACCAAGCATTCATGAAGGTACTGAAAAAACAGAACCTCAACATCACATAGGTAAT
    CAAACTGAATCTAATCATGATGAAGATCATGACATCACTTCGGAGTCAGTAGAATCAGCA
    GAATCAGTTAAACAAGCACCACAAAGTGACGATTTAACAAACGATTCAAATGAAGATGAA
    ATAGAGCAATCATTAAAAGAACCTGCGACTTATAAAGAAGACAGACGTTCATCAGTTGTA
    ATTGATGCAGAAAAACATATCGAAAAAACTGAAGAACAATCTTCAGATAAAAACAAATAA
    60
    120
    180
    240
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    360
    420
    480
    540
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    840
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    1020
    1080
    1140
    1200
    1260

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS12215 [old locus tag: SA2126 ]
  • symbol: SA_RS12215
  • description: lysostaphin resistance protein A
  • length: 419
  • theoretical pI: 4.68169
  • theoretical MW: 46785
  • GRAVY: 0.0937947

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: see SA2126
  • PFAM:
    no clan defined Kinocilin; Kinocilin protein (PF15033; HMM-score: 15.8)
    Peptidase_U (CL0472) Abi; CAAX protease self-immunity (PF02517; HMM-score: 14)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 8
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.015793
    • TAT(Tat/SPI): 0.000177
    • LIPO(Sec/SPII): 0.020214
  • predicted transmembrane helices (TMHMM): 8

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKNNKISGFQWAMTIFVFFVITMALSIMLRDFQSIIGVKHFIFEVTDLAPLIAAIICILVFKYKKVQLAGLKFSISLKVIERLLLALILPLIILIIGMYSFNTFADSFILLQSTGLSVPITHILIGHILMAFVVEFGFRSYLQNIVETKMNTFFASIVVGLMYSVFSANTTYGTEFAAYNFLYTFSFSMILGELIRATKGRTIYIATTFHASMTFGLIFLFSEEIGDLFSIKVIAISTAIVAVGYIGLSLIIRGIAYLTTRRNLEELEPNNYLDHVNDDEETNHTEAEKSSSNIKDAEKTGVATASTVGVAKNDTENTVADEPSIHEGTEKTEPQHHIGNQTESNHDEDHDITSESVESAESVKQAPQSDDLTNDSNEDEIEQSLKEPATYKEDRRSSVVIDAEKHIEKTEEQSSDKNK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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