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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS12745 [old locus tag: SA2219 ]
  • pan locus tag?: SAUPAN005978000
  • symbol: SA_RS12745
  • pan gene symbol?: —
  • synonym:
  • product: GtrA family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS12745 [old locus tag: SA2219 ]
  • symbol: SA_RS12745
  • product: GtrA family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2491623..2492009
  • length: 387
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (2491623..2492009) NCBI
  • BioCyc: SA_RS12745 BioCyc
  • MicrobesOnline: see SA2219

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGAAACTAACACAAACGCATGCTGAAATTTTAAAATTTATCATTGTTGGCGGCATTAAT
    ACGTTAAATTATTATGTTGTCTATTTATTGCTGTTAAAATTATTACACATTGAATATATG
    ATTAGTCATATTACCGGATTTCTAGTCGCTTTTGTGATTTCGTATTATTTGAATTGTTAT
    TTTGTTTACAGGGTAAAACCTACTTGGAGAAAATTCATTAGTTTTCCAATTACGCAGATT
    GTCAACGTAAGCTTACAAACAGTTTTATTATATGTTTTTGTATCCTGGCTAAATTTGCCA
    GCGGAAATTGCGCCATTTGCAGGTTTAGTGATTACGATACCCATCACATTTGTATTATCT
    AAATGGATTTTAAAAGATAGTAATTAA
    60
    120
    180
    240
    300
    360
    387

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS12745 [old locus tag: SA2219 ]
  • symbol: SA_RS12745
  • description: GtrA family protein
  • length: 128
  • theoretical pI: 9.70953
  • theoretical MW: 14864.8
  • GRAVY: 0.907812

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: see SA2219
  • PFAM:
    no clan defined GtrA; GtrA-like protein (PF04138; HMM-score: 82.4)
    and 2 more
    DUF4229; Protein of unknown function (DUF4229) (PF14012; HMM-score: 8.3)
    MNHE; Na+/H+ ion antiporter subunit (PF01899; HMM-score: 7.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.000708
    • TAT(Tat/SPI): 0.000085
    • LIPO(Sec/SPII): 0.012672
  • predicted transmembrane helices (TMHMM): 4

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKLTQTHAEILKFIIVGGINTLNYYVVYLLLLKLLHIEYMISHITGFLVAFVISYYLNCYFVYRVKPTWRKFISFPITQIVNVSLQTVLLYVFVSWLNLPAEIAPFAGLVITIPITFVLSKWILKDSN

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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