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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS13515 [old locus tag: SA2358 ]
  • pan locus tag?: SAUPAN006240000
  • symbol: SA_RS13515
  • pan gene symbol?:
  • synonym:
  • product: TetR family transcriptional regulator

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS13515 [old locus tag: SA2358 ]
  • symbol: SA_RS13515
  • product: TetR family transcriptional regulator
  • replicon: chromosome
  • strand: +
  • coordinates: 2650900..2651469
  • length: 570
  • essential: no DEG other strains

Accession numbers[edit | edit source]

  • Location: NC_002745 (2650900..2651469) NCBI
  • BioCyc: G1G21-2744 BioCyc
  • MicrobesOnline: see SA2358

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGATGGAAAGTAAATCCATAGATCCAAGAATCGTTAGAACCAAACAATTGCTTGTCGAT
    GCTTTTCTTAAAATTTCTAGAGAAAAGAAATTATCTCAAATTACAGTTAAAGATATCACT
    GATATTGCTACGCTAAATCGTGCAACATTTTACGCTCATTTCACTGATAAAGAAGACCTC
    CTAGACTACACATTATCTGTAACCATTTTAAAAGACTTGAATGATAACTTGAGCATTTCT
    AATGTCATTAATGAAAAGGTGCTGCGTAATATTTTCATTTCAATTGCGAGTTATATCAAA
    GATGCTGCAAAGTCTTGCGAATTAAATAGTGAAGCATTTTGCAACAAAGCACATCAACGT
    ATTAATAATGAATTAGAAGATATTTTTGCGATTATGTTAGAAAACAGCTATCCGGAGCAT
    CAACGAGATATCATTGTAAATAGTGCGAGTTTTTTAGCAGCTGGTATCTCAGGCTTAGCA
    TTACATTGGTTTAACACGAGTCAAGAGACAGCCGATGTGTTTATCGATCGCAACCTTCCA
    TTTTTAATTCATCATATAGCACATTTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    570

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS13515 [old locus tag: SA2358 ]
  • symbol: SA_RS13515
  • description: TetR family transcriptional regulator
  • length: 189
  • theoretical pI: 6.15092
  • theoretical MW: 21585.5
  • GRAVY: -0.0624339

Function[edit | edit source]

  • TIGRFAM:
    probable dihydroxyacetone kinase regulator (TIGR02366; HMM-score: 40.4)
    and 2 more
    Signal transduction Regulatory functions DNA interactions transcriptional repressor BetI (TIGR03384; HMM-score: 20.5)
    Signal transduction Regulatory functions DNA interactions mycofactocin system transcriptional regulator (TIGR03968; HMM-score: 16.5)
  • TheSEED: see SA2358
  • PFAM:
    HTH (CL0123) TetR_N; Bacterial regulatory proteins, tetR family (PF00440; HMM-score: 27.8)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helix: 1
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002276
    • TAT(Tat/SPI): 0.000145
    • LIPO(Sec/SPII): 0.000324
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MMESKSIDPRIVRTKQLLVDAFLKISREKKLSQITVKDITDIATLNRATFYAHFTDKEDLLDYTLSVTILKDLNDNLSISNVINEKVLRNIFISIASYIKDAAKSCELNSEAFCNKAHQRINNELEDIFAIMLENSYPEHQRDIIVNSASFLAAGISGLALHWFNTSQETADVFIDRNLPFLIHHIAHF

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]