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NCBI: 06-JUL-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_1088 [new locus tag: NWMN_RS06170 ]
  • pan locus tag?: SAUPAN003448000
  • symbol: NWMN_1088
  • pan gene symbol?: mraZ
  • synonym:
  • product: cell division protein MraZ

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_1088 [new locus tag: NWMN_RS06170 ]
  • symbol: NWMN_1088
  • product: cell division protein MraZ
  • replicon: chromosome
  • strand: +
  • coordinates: 1192053..1192484
  • length: 432
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGTTCATGGGAGAATACGATCATCAATTAGATACAAAAGGACGTATGATTATACCGTCC
    AAGTTTCGTTATGACTTAAATGAGCGTTTTATTATCACAAGAGGCCTTGATAAATGTTTA
    TTCGGTTACACTCTAGACGAATGGCAACAGATTGAAGAGAAAATGAAAACCTTACCTATG
    ACAAAAAAAGACGCACGTAAGTTTATGCGTATGTTCTTCTCTGGTGCTGTTGAAGTAGAA
    CTTGATAAGCAAGGGCGTATTAACATCCCTCAAAACTTGAGGAAATACGCTAATTTAACT
    AAAGAATGTACAGTAATCGGTGTTTCAAATCGTATTGAGATTTGGGATAGAGAAACTTGG
    AATGATTTCTATGAAGAATCTGAAGAAAGTTTCGAAGATATTGCTGAAGATTTAATAGAT
    TTTGATTTTTAA
    60
    120
    180
    240
    300
    360
    420
    432

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_1088 [new locus tag: NWMN_RS06170 ]
  • symbol: NWMN_1088
  • description: cell division protein MraZ
  • length: 143
  • theoretical pI: 4.52156
  • theoretical MW: 17237.5
  • GRAVY: -0.646154

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Cellular processesCellular processesCell divisiondivision/cell wall cluster transcriptional repressor MraZ (TIGR00242; HMM-score: 185.8)
    Signal transductionRegulatory functionsDNA interactionsdivision/cell wall cluster transcriptional repressor MraZ (TIGR00242; HMM-score: 185.8)
    Signal transductionRegulatory functionsDNA interactionstranscriptional regulator, AbrB family (TIGR01439; HMM-score: 22.8)
    Hypothetical proteinsConservedTIGR02922 family protein (TIGR02922; HMM-score: 14.1)
  • TheSEED:  
    Cell Division and Cell CycleCell Division and Cell Cycle - no subcategoryBacterial Cytoskeleton Cell division protein MraZ 
    Bacterial Cell Division Cell division protein MraZ 
  • PFAM:
    AbrB (CL0132) MraZ; MraZ protein, putative antitoxin-like (PF02381; HMM-score: 175.3)
    no clan definedDUF2375; Protein of unknown function (DUF2375) (PF09558; HMM-score: 14.9)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.092
    • Ymax_pos: 70
    • Cmax: 0.104
    • Cmax_pos: 52
    • Smax: 0.101
    • Smax_pos: 4
    • Smean: 0.071
    • D: 0.084
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MFMGEYDHQLDTKGRMIIPSKFRYDLNERFIITRGLDKCLFGYTLDEWQQIEEKMKTLPMTKKDARKFMRMFFSGAVEVELDKQGRINIPQNLRKYANLTKECTVIGVSNRIEIWDRETWNDFYEESEESFEDIAEDLIDFDF

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]