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NCBI: 06-JUL-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_1095 [new locus tag: NWMN_RS06205 ]
  • pan locus tag?: SAUPAN003455000
  • symbol: ftsA
  • pan gene symbol?: ftsA
  • synonym:
  • product: cell division protein FtsA

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_1095 [new locus tag: NWMN_RS06205 ]
  • symbol: ftsA
  • product: cell division protein FtsA
  • replicon: chromosome
  • strand: +
  • coordinates: 1200114..1201526
  • length: 1413
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGGAAGAACATTACTACGTAAGTATTGATATTGGATCATCAAGCGTAAAAACAATAGTA
    GGCGAGAAATTTCACAATGGTATAAATGTGATAGGTACAGGACAAACCTACACGAGCGGT
    ATAAAAAATGGTTTAATTGATGATTTTGATATTGCGCGACAAGCAATCAAAGACACAATT
    AAAAAGGCATCAATCGCTTCGGGTGTTGATATTAAAGAAGTTTTCCTGAAATTACCTATC
    ATTGGAACGGAAGTTTATGATGAATCAAATGAAATCGACTTTTATGAGGATACAGAAATC
    AACGGTTCACATATCGAAAAAGTATTAGAAGGTATTAGAGAAAAAAATGATGTGCAAGAA
    ACAGAAGTAATTAATGTGTTCCCGATTCGTTTTATAGTCGATAAAGAAAATGAGGTTTCA
    GACCCTAAAGAATTAATTGCCAGACATTCATTAAAGGTTGAAGCAGGCGTAATTGCTATT
    CAAAAATCGATTTTAATTAATATGATTAAATGCGTAGAAGCATGTGGTGTTGATGTATTA
    GATGTTTACTCTGATGCATATAACTATGGTTCAATCCTAACAGCTACTGAAAAAGAGTTA
    GGTGCATGTGTCATTGATATTGGTGAAGACGTTACGCAAGTTGCTTTTTATGAACGCGGT
    GAATTAGTAGATGCTGATTCTATCGAAATGGCAGGGCGTGATATTACAGACGATATTGCA
    CAAGGATTAAACACTTCTTATGAAACTGCTGAAAAAGTTAAACACCAATATGGTCATGCA
    TTCTATGATTCTGCTTCAGATCAAGATATCTTCACTGTTGAACAGGTTGATAGTGATGAA
    ACAGTACAGTATACTCAAAAAGATTTGAGTGACTTTATTGAAGCGCGTGTAGAAGAAATA
    TTCTTCGAAGTATTTGATGTTTTACAAGATTTAGGATTAACAAAAGTAAATGGTGGGTTT
    ATTGTAACTGGTGGATCTGCAAACTTACTTGGCGTAAAAGAATTATTATCAGATATGGTA
    AGTGAAAAAGTTAGAATTCACACGCCATCACAAATGGGAATTAGAAAACCTGAATTTTCT
    TCAGCAATTTCTACAATTTCTAGTAGTATCGCTTTTGATGAGTTATTAGATTATGTTACA
    ATTAATTATCATGATAATGAAGAAACTGAAGAAGATGTTATTGATGTGAAAGACAAAGAT
    AACGAATCTAAATTAGGCGGATTTGATTGGTTTAAACGTAAAACAAACAAAAAAGATACT
    CATGAAAATGAAGTAGAGTCAACAGATGAAGAAATTTATCAATCAGAAGATAATCATCAG
    GAACATAAACAGAATCATGAACATGTTCAAGACAAAGATAAAGATAAAGAAGAAAGTAAA
    TTCAAAAAACTAATGAAATCTCTATTTGAATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1413

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_1095 [new locus tag: NWMN_RS06205 ]
  • symbol: FtsA
  • description: cell division protein FtsA
  • length: 470
  • theoretical pI: 4.21772
  • theoretical MW: 52934.3
  • GRAVY: -0.464468

Function[edit source | edit]

  • TIGRFAM:
    Cellular processesCellular processesCell divisioncell division protein FtsA (TIGR01174; HMM-score: 273.4)
    and 3 more
    Cell structureCell envelopeBiosynthesis and degradation of murein sacculus and peptidoglycancell shape determining protein, MreB/Mrl family (TIGR00904; HMM-score: 39.7)
    type IV pilus assembly protein PilM (TIGR01175; HMM-score: 28.7)
    ethanolamine utilization protein EutJ family protein (TIGR02529; HMM-score: 20.1)
  • TheSEED:  
    Cell Division and Cell CycleCell Division and Cell Cycle - no subcategoryBacterial Cytoskeleton Cell division protein FtsA
    and 4 more
    Clustering-based subsystemsCell DivisionCell Division Cluster Cell division protein FtsA
    cell division cluster containing FtsQ Cell division protein FtsA
    Bacterial Cell Division Cell division protein FtsA
    RP Bacterial Cell Division Cell division protein FtsA
  • PFAM:
    Actin_ATPase (CL0108) FtsA; Cell division protein FtsA (PF14450; HMM-score: 90.5)
    and 6 more
    MreB_Mbl; MreB/Mbl protein (PF06723; HMM-score: 55.2)
    SHS2 (CL0319) SHS2_FTSA; SHS2 domain inserted in FTSA (PF02491; HMM-score: 42.6)
    Actin_ATPase (CL0108) PilM_2; Type IV pilus assembly protein PilM; (PF11104; HMM-score: 28.3)
    no clan definedDUF2410; Hypothetical protein (DUF2410) (PF10307; HMM-score: 18.2)
    Actin_ATPase (CL0108) BcrAD_BadFG; BadF/BadG/BcrA/BcrD ATPase family (PF01869; HMM-score: 17.3)
    no clan definedBDM; Putative biofilm-dependent modulation protein (PF10684; HMM-score: 15.1)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.138
    • Ymax_pos: 33
    • Cmax: 0.141
    • Cmax_pos: 23
    • Smax: 0.218
    • Smax_pos: 22
    • Smean: 0.118
    • D: 0.13
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MEEHYYVSIDIGSSSVKTIVGEKFHNGINVIGTGQTYTSGIKNGLIDDFDIARQAIKDTIKKASIASGVDIKEVFLKLPIIGTEVYDESNEIDFYEDTEINGSHIEKVLEGIREKNDVQETEVINVFPIRFIVDKENEVSDPKELIARHSLKVEAGVIAIQKSILINMIKCVEACGVDVLDVYSDAYNYGSILTATEKELGACVIDIGEDVTQVAFYERGELVDADSIEMAGRDITDDIAQGLNTSYETAEKVKHQYGHAFYDSASDQDIFTVEQVDSDETVQYTQKDLSDFIEARVEEIFFEVFDVLQDLGLTKVNGGFIVTGGSANLLGVKELLSDMVSEKVRIHTPSQMGIRKPEFSSAISTISSSIAFDELLDYVTINYHDNEETEEDVIDVKDKDNESKLGGFDWFKRKTNKKDTHENEVESTDEEIYQSEDNHQEHKQNHEHVQDKDKDKEESKFKKLMKSLFE

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]