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NCBI: 06-JUL-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_1159 [new locus tag: NWMN_RS06535 ]
  • pan locus tag?: SAUPAN003545000
  • symbol: NWMN_1159
  • pan gene symbol?: dprA
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_1159 [new locus tag: NWMN_RS06535 ]
  • symbol: NWMN_1159
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1271729..1272601
  • length: 873
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    TTGATTAAACTATTTTTGCTTAAGTTATACTGGGCACACTTTTCGACTAAACAAATTCAT
    CAATTTTTAATGGCATATCCTAATGTAATTAAAGAGGAGGGAAGAAAAAAAGATAGTTAT
    TTATGTGAATGGGTGAATAGGGAAGAAAATGTTCATTTATTACGTAAATACTATGCTTTT
    ATAAAACTTGATCATAACGATATTATTAAAGAACTGCAGAAATTAAAAGTAAGTTACATT
    ACATATATGGATTCTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTT
    CTTTTCTATAAAGGGAACATCAAATTAATAAATAATATGCATCATTTGGCAGTAGTAGGT
    GCAAGAGATTCTACAAGTTATACCCAACAGTCTTTAGAATTTTTATTATCAAATGATAAA
    AGCAAATATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
    ATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACAT
    TATCCCAAAAGTACATTAGCATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCT
    GAATATCCACCACATACACCAATCGCTAAATATAGATTTCCTGAGCGCAATAGAATTATC
    AGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
    ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTT
    AATCCTATGACAAAAGGTAATTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAAC
    GCTAATGATATATTTGAAGACTACTATATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    873

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_1159 [new locus tag: NWMN_RS06535 ]
  • symbol: NWMN_1159
  • description: hypothetical protein
  • length: 290
  • theoretical pI: 9.51915
  • theoretical MW: 33564.7
  • GRAVY: -0.203103

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Cellular processesCellular processesDNA transformationDNA protecting protein DprA (TIGR00732; HMM-score: 219.3)
  • TheSEED:  
    RNA MetabolismRNA processing and modificationYrdC-YciO-Sua5 and associated protein families Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake 
    Conserved gene cluster associated with Met-tRNA formyltransferase Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake 
  • PFAM:
    DprA (CL0349) DNA_processg_A; DNA recombination-mediator protein A (PF02481; HMM-score: 234.9)
    MoCo_carrier; Putative molybdenum carrier (PF12694; HMM-score: 19.2)
    no clan definedDUF2493; Protein of unknown function (DUF2493) (PF10686; HMM-score: 12.7)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.17
    • Ymax_pos: 13
    • Cmax: 0.121
    • Cmax_pos: 26
    • Smax: 0.345
    • Smax_pos: 11
    • Smean: 0.289
    • D: 0.217
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MIKLFLLKLYWAHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEWVNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYITYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQIALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHITIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]