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NCBI: 06-JUL-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_1172 [new locus tag: NWMN_RS06610 ]
  • pan locus tag?: SAUPAN003563000
  • symbol: NWMN_1172
  • pan gene symbol?: rasP
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_1172 [new locus tag: NWMN_RS06610 ]
  • symbol: NWMN_1172
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1286208..1287494
  • length: 1287
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    GTGAGCTATTTAGTTACAATAATTGCATTTATTATTGTTTTTGGTGTACTAGTAACTGTT
    CATGAATATGGCCATATGTTTTTTGCGAAAAGAGCAGGCATTATGTGTCCAGAATTTGCG
    ATCGGTATGGGGCCAAAAATTTTTAGTTTTAGAAAAAATGAAACACTTTACACTATTAGG
    TTATTGCCTGTTGGTGGATATGTTCGTATGGCAGGAGATGGCTTAGAAGAGCCACCAGTC
    GAGCCCGGTATGAACGTTAAAATTAAACTTAATGAAGAAAATGAAATAACACATATCATA
    TTAGATGATCATCATAAGTTTCAACAAATTGAAGCGATCGAAGTTAAAAAATGTGATTTT
    AAGGATGACTTATTCATAGAAGGTATCACTGCTTATGATAATGAAAGACATCATTTTAAA
    ATTGCTAGAAAGTCTTTCTTTGTTGAAAATGGTAGCTTAGTTCAAATTGCTCCGAGAGAC
    AGACAATTTGCACATAAAAAGCCATGGCCGAAATTTTTAACATTATTTGCGGGACCGTTA
    TTTAACTTTATATTAGCTTTAGTCCTATTTATTGGTCTTGCATATTATCAAGGCACGCCT
    ACGTCTACTGTAGAACAAGTCGCAGATAAGTATCCAGCTCAACAAGCAGGATTACAAAAA
    GGTGATAAGATCGTCCAAATTGGCAAATATAAAATATCTGAATTTGATGATGTTGATAAG
    GCGTTAGATAAAGTTAAAGATAATAAGACGACTGTTAAATTTGAACGTGATGGTAAAACA
    AAGTCAGTTGAATTAACACCTAAAAAGACTGAAAAAAAACTGACTAAAGTAAGTTCAGAG
    ACGAAGTATGTTCTCGGATTCCAACCAGCGAGTGAACATACACTTTTTAAACCAATTGTA
    TTCGGATTTAAAAGCTTTTTAATCGGTAGTACTTATATTTTTACAGCTGTAGTAGGTATG
    TTGGCTAGTATATTTACGGGCGGATTCTCATTTGATATGTTAAATGGTCCGGTTGGTATT
    TATCATAACGTCGACTCAGTTGTTAAAGCGGGTATCATTAGCTTAATTGGTTACACTGCG
    TTATTAAGTGTAAACTTAGGTATTATGAATTTAATTCCTATTCCTGCACTAGACGGTGGT
    CGTATTTTATTTGTTATATATGAAGCGATTTTCAGAAAACCAGTTAATAAAAAAGCGGAA
    ACAACGATTATTGCTATTGGTGCCATTTTCATGGTCGTTATAATGATATTAGTAACGTGG
    AATGATATTCGACGATATTTCTTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1287

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_1172 [new locus tag: NWMN_RS06610 ]
  • symbol: NWMN_1172
  • description: hypothetical protein
  • length: 428
  • theoretical pI: 9.54429
  • theoretical MW: 48106.2
  • GRAVY: 0.175234

Function[edit source | edit]

  • reaction:
    EC 3.4.24.-?  ExPASy
  • TIGRFAM:
    Genetic information processingProtein fateDegradation of proteins, peptides, and glycopeptidesRIP metalloprotease RseP (TIGR00054; EC 3.4.24.-; HMM-score: 287.4)
    Genetic information processingProtein fateDegradation of proteins, peptides, and glycopeptidespeptidase Do (TIGR02037; EC 3.4.21.-; HMM-score: 37.8)
    Genetic information processingProtein fateProtein folding and stabilizationpeptidase Do (TIGR02037; EC 3.4.21.-; HMM-score: 37.8)
    Cellular processesCellular processesSporulation and germinationstage IV sporulation protein B (TIGR02860; EC 3.4.21.116; HMM-score: 29.5)
    Genetic information processingProtein fateDegradation of proteins, peptides, and glycopeptidesC-terminal processing peptidase (TIGR00225; EC 3.4.21.-; HMM-score: 27)
    Genetic information processingProtein fateProtein modification and repairC-terminal processing peptidase (TIGR00225; EC 3.4.21.-; HMM-score: 27)
    putative carboxyl-terminal-processing protease, deltaproteobacterial (TIGR03900; EC 3.4.21.-; HMM-score: 19.2)
    Genetic information processingProtein fateProtein and peptide secretion and traffickingtype II secretion system protein C (TIGR01713; HMM-score: 15.9)
  • TheSEED:  
    Regulation and Cell signalingRegulation and Cell signaling - no subcategorySex pheromones in Enterococcus faecalis and other Firmicutes Membrane-associated zinc metalloprotease 
    Stress ResponsePeriplasmic StressPeriplasmic Stress Response Membrane-associated zinc metalloprotease 
  • PFAM:
    Peptidase_MA (CL0126) Peptidase_M50; Peptidase family M50 (PF02163; HMM-score: 254.2)
    PDZ-like (CL0466) PDZ_2; PDZ domain (PF13180; HMM-score: 44.2)
    PDZ; PDZ domain (Also known as DHR or GLGF) (PF00595; HMM-score: 23.3)
    Tricorn_PDZ; Tricorn protease PDZ domain (PF14685; HMM-score: 13.3)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors: Zn2+
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 5
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.151
    • Ymax_pos: 23
    • Cmax: 0.201
    • Cmax_pos: 23
    • Smax: 0.302
    • Smax_pos: 4
    • Smean: 0.157
    • D: 0.153
  • predicted transmembrane helices (TMHMM): 5

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MSYLVTIIAFIIVFGVLVTVHEYGHMFFAKRAGIMCPEFAIGMGPKIFSFRKNETLYTIRLLPVGGYVRMAGDGLEEPPVEPGMNVKIKLNEENEITHIILDDHHKFQQIEAIEVKKCDFKDDLFIEGITAYDNERHHFKIARKSFFVENGSLVQIAPRDRQFAHKKPWPKFLTLFAGPLFNFILALVLFIGLAYYQGTPTSTVEQVADKYPAQQAGLQKGDKIVQIGKYKISEFDDVDKALDKVKDNKTTVKFERDGKTKSVELTPKKTEKKLTKVSSETKYVLGFQPASEHTLFKPIVFGFKSFLIGSTYIFTAVVGMLASIFTGGFSFDMLNGPVGIYHNVDSVVKAGIISLIGYTALLSVNLGIMNLIPIPALDGGRILFVIYEAIFRKPVNKKAETTIIAIGAIFMVVIMILVTWNDIRRYFL

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]