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NCBI: 06-JUL-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_2155 [new locus tag: NWMN_RS12440 ]
  • pan locus tag?: SAUPAN005705000
  • symbol: NWMN_2155
  • pan gene symbol?: pbuG
  • synonym:
  • product: xanthine/uracil permeases family protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_2155 [new locus tag: NWMN_RS12440 ]
  • symbol: NWMN_2155
  • product: xanthine/uracil permeases family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2376805..2378139
  • length: 1335
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    GTGAAAAACTATTTCCAGTTCGATAAATATGGAACAAACTTTAAAAGAGAAATCTTAGGC
    GGTATCACAACTTTCTTATCTATGGCCTATATTTTAGCAGTTAACCCGCAAGTTTTAAGT
    TTAGCAGGTGTTAAAGGCGTATCAGAAGATATGAAAATGGACCAAGGTGCCATTTTTGTA
    GCGACTGCATTAGCAGCATTTGTAGGCTCGCTATTCATGGGGCTAATAGCTAAATATCCA
    ATTGCGTTAGCACCAGGTATGGGATTAAATGCATTCTTTGCATTTACTGTTGTGTTAACC
    ATGGGTATTCCTTGGCAAGTTGGTTTAACAGGCGTTTTATTCTCAGGTATATTCTTTGCG
    ATATTAACCGTCACAGGGTTTAGGGAAGTTATTATTAATGCAATTCCTTATCAAATGAAG
    ATGGCTGTTTCAGCAGGTATAGGATTATTCATTACATTTGTAGGTTTACAAAGTTCGGGT
    ATTATAGTTAAAAATGAATCTACATTAGTAACATTGGGACATTTAACTGATCCACCAGTA
    CTTTTGGCGATATTCGGTATCGTTATTACAGTTATTTTATATGCAATTAAATTGCCGGGT
    TCTATCTTTATCGGTATGATCATCACAGCAATCGTTGGTATGTTCACTGGATTGATTCAA
    ATGCCATCTGGTATTGTGGGTAAGATTCCAAGTATTGAACCAACGTTCGGTGCTGCATTT
    GAAGCGTTTAAAGACCCAAGTCAATTATTAACGATACAGTTCTTAATTGTTATTTTAACG
    TTCTTATTTATTGATTTCTTTGATACAGCTGGTACATTAGTAGCTGTTGCTACTCAAGCA
    GGTATTATGAAAGATAATAAATTACCAAGAGCTGGTAGAGCATTGTTCTCAGATTCTTTA
    GCTACGATTGTAGGATCAGTTTTTGGAACAACTACAACAACTTCTTATATCGAATCAACT
    TCAGGTGTTGCTGTAGGTGCTAGAACAGGATTTGCTAGTATCGTAACAGGTTGTTGTTTC
    CTATTAGCGCTGTTCTTTAGTCCGTTAATCGCTGTTGTAACAAGTGCAGTTACGACACCA
    GCCTTAGTGGTGGTAGGTGTATTAATGGCTGCAAACTTTGCTGAGATAAACTGGAAAAGT
    TTTGAAGTTGCAGTGCCAGCCTTCATTACAATCATTATGATGCCTTTATCATATTCAATT
    GCAACTGGTATTGCGTGTGGATTTATTTTCTATCCAATTACAATGCTTATCTCTAAAAAA
    CATAAAGAAGTACATCCGATAATGTATGTATTAATGGTACTATTCATTCTGTACTTCATA
    TTTGTTCATGGTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1335

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_2155 [new locus tag: NWMN_RS12440 ]
  • symbol: NWMN_2155
  • description: xanthine/uracil permeases family protein
  • length: 444
  • theoretical pI: 8.72068
  • theoretical MW: 47395.5
  • GRAVY: 1.05068

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismTransport and binding proteinsNucleosides, purines and pyrimidinesuracil-xanthine permease (TIGR00801; HMM-score: 13.4)
  • TheSEED:  
    Nucleosides and NucleotidesPurinesXanthine Metabolism in Bacteria Hypoxanthine/guanine permease PbuG 
  • PFAM:
    APC (CL0062) Xan_ur_permease; Permease family (PF00860; HMM-score: 143.1)
    no clan definedDUF5464; Family of unknown function (DUF5464) (PF17552; HMM-score: 13.1)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 13
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.179
    • Ymax_pos: 43
    • Cmax: 0.141
    • Cmax_pos: 43
    • Smax: 0.407
    • Smax_pos: 40
    • Smean: 0.189
    • D: 0.183
  • predicted transmembrane helices (TMHMM): 13

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MKNYFQFDKYGTNFKREILGGITTFLSMAYILAVNPQVLSLAGVKGVSEDMKMDQGAIFVATALAAFVGSLFMGLIAKYPIALAPGMGLNAFFAFTVVLTMGIPWQVGLTGVLFSGIFFAILTVTGFREVIINAIPYQMKMAVSAGIGLFITFVGLQSSGIIVKNESTLVTLGHLTDPPVLLAIFGIVITVILYAIKLPGSIFIGMIITAIVGMFTGLIQMPSGIVGKIPSIEPTFGAAFEAFKDPSQLLTIQFLIVILTFLFIDFFDTAGTLVAVATQAGIMKDNKLPRAGRALFSDSLATIVGSVFGTTTTTSYIESTSGVAVGARTGFASIVTGCCFLLALFFSPLIAVVTSAVTTPALVVVGVLMAANFAEINWKSFEVAVPAFITIIMMPLSYSIATGIACGFIFYPITMLISKKHKEVHPIMYVLMVLFILYFIFVHG

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]