NCBI: 06-JUL-2013
Contents
⊟Summary[edit source | edit]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_2213 [new locus tag: NWMN_RS12765 ]
- pan locus tag?: SAUPAN005790000
- symbol: NWMN_2213
- pan gene symbol?: —
- synonym:
- product: DeoR family regulatory protein
⊟Genome View[edit source | edit]
⊟Gene[edit source | edit]
⊟General[edit source | edit]
- type: CDS
- locus tag: NWMN_2213 [new locus tag: NWMN_RS12765 ]
- symbol: NWMN_2213
- product: DeoR family regulatory protein
- replicon: chromosome
- strand: +
- coordinates: 2435325..2436017
- length: 693
- essential: unknown other strains
⊟Accession numbers[edit source | edit]
- Gene ID: 5331337 NCBI
- RefSeq: YP_001333247 NCBI
- MicrobesOnline: 3707815 MicrobesOnline
⊟Phenotype[edit source | edit]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit source | edit]
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661ATGAATAAAGCTGAAAGGCAAAATTTAATAATTACTGCAATTCAACAAAATAAAAAAATG
ACCGCTTTAGAATTAGCTAAATATTGCAACGTATCCAAACGCACAATTTTAAGAGATATT
GATGATTTAGAAAATCAAGGTGTTAAAATTTATGCGCATTATGGGAAAAATGGTGGTTAC
CAAATACAACAAGCACAATCTAAAATTGCATTAAACTTATCTGAAACACAATTATCAGCC
TTATTTTTAGTGCTTAATGAAAGTCAGTCGTACTCGACATTACCATATAAAAGCGAAATC
AACGCAATTATAAAACAATGTTTAAGTCTTCCACAAACACGCTTAAGAAAATTGCTTAAA
CGCATGGACTTTTATATTAAATTTGATGACACACAACATATGACACTCCCAATGCTGTTT
TCCGACATTTTAATTTATTGTACAGAACGAAATGTGATGTTAGTAGATCATAGGGTTGAT
GATAATATTAAAGCTGAAAACGTTATATTTATTGGCCTTTTGTGTAAACATGGACATTGG
CATGCAGTCATTTATGACATTGCTCAAGACAAAACTGCCGAACTCGAAATTGAAAATATT
ATAGATATTTCGTATTCATTCGGTAAGACGATTCAAACCAGAGACATATCCATTGATAAC
TATCATCAATTTTTAAACCCCATCGATTCCTAA60
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⊟Protein[edit source | edit]
⊟General[edit source | edit]
- locus tag: NWMN_2213 [new locus tag: NWMN_RS12765 ]
- symbol: NWMN_2213
- description: DeoR family regulatory protein
- length: 230
- theoretical pI: 7.17682
- theoretical MW: 26618.5
- GRAVY: -0.268261
⊟Function[edit source | edit]
- reaction:
- TIGRFAM: Unknown functionGeneralRrf2 family protein (TIGR00738; HMM-score: 17.7)DNA metabolismDNA replication, recombination, and repairDnaD family protein (TIGR04548; HMM-score: 16.8)Regulatory functionsDNA interactionsCRISPR locus-related DNA-binding protein (TIGR01884; HMM-score: 15.5)Biosynthesis of cofactors, prosthetic groups, and carriersOtherFeS assembly SUF system regulator (TIGR02944; HMM-score: 15)Regulatory functionsDNA interactionsFeS assembly SUF system regulator (TIGR02944; HMM-score: 15)Unknown functionGeneralDNA binding domain, excisionase family (TIGR01764; HMM-score: 14)Biosynthesis of cofactors, prosthetic groups, and carriersOtheriron-sulfur cluster biosynthesis transcriptional regulator SufR (TIGR02702; HMM-score: 13)Regulatory functionsDNA interactionsiron-sulfur cluster biosynthesis transcriptional regulator SufR (TIGR02702; HMM-score: 13)Regulatory functionsDNA interactionsbiotin operon repressor (TIGR00122; HMM-score: 12.1)
- TheSEED:
- PFAM: HTH (CL0123) HTH_11; HTH domain (PF08279; HMM-score: 49.1)HTH_DeoR; DeoR-like helix-turn-helix domain (PF08220; HMM-score: 36.6)Rrf2; Transcriptional regulator (PF02082; HMM-score: 25.5)HTH_24; Winged helix-turn-helix DNA-binding (PF13412; HMM-score: 20.6)HTH_Mga; M protein trans-acting positive regulator (MGA) HTH domain (PF08280; HMM-score: 18)TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP) (PF07106; HMM-score: 16.4)HTH_36; Helix-turn-helix domain (PF13730; HMM-score: 16.3)HTH_AsnC-type; AsnC-type helix-turn-helix domain (PF13404; HMM-score: 14.9)HTH_Crp_2; Crp-like helix-turn-helix domain (PF13545; HMM-score: 13.4)MarR; MarR family (PF01047; HMM-score: 13.3)Tn7_Tnp_TnsA_C; TnsA endonuclease C terminal (PF08721; HMM-score: 12.8)TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 11.9)
⊟Structure, modifications & interactions[edit source | edit]
- domains:
- modifications:
- cofactors:
- effectors:
- protein partners:
⊟Localization[edit source | edit]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0.32
- Cytoplasmic Membrane Score: 9.55
- Cellwall Score: 0.12
- Extracellular Score: 0.01
- Internal Helices: 0
- LocateP: Intracellular
- Prediction by SwissProt Classification: Cytoplasmic
- Pathway Prediction: No pathway
- Intracellular Possibility: 1
- Signal Peptide Possibility: -1
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- Ymax: 0.15
- Ymax_pos: 23
- Cmax: 0.126
- Cmax_pos: 23
- Smax: 0.206
- Smax_pos: 15
- Smean: 0.162
- D: 0.154
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit source | edit]
⊟Protein sequence[edit source | edit]
- MNKAERQNLIITAIQQNKKMTALELAKYCNVSKRTILRDIDDLENQGVKIYAHYGKNGGYQIQQAQSKIALNLSETQLSALFLVLNESQSYSTLPYKSEINAIIKQCLSLPQTRLRKLLKRMDFYIKFDDTQHMTLPMLFSDILIYCTERNVMLVDHRVDDNIKAENVIFIGLLCKHGHWHAVIYDIAQDKTAELEIENIIDISYSFGKTIQTRDISIDNYHQFLNPIDS
⊟Experimental data[edit source | edit]
- experimentally validated: no data available
⊟Expression & Regulation[edit source | edit]
⊟Operon[edit source | edit]
- MicrobesOnline: NWMN_2213 no polycistronic organisation predicted
⊟Regulation[edit source | edit]
- sigma factor:
- regulator: CcpA
CcpA (TF) important in Carbon catabolism RegPrecise
⊟Transcription pattern[edit source | edit]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit source | edit]
- Aureolib: no data available
⊟Protein stability[edit source | edit]
- half-life: no data available
⊟Biological Material[edit source | edit]
⊟Mutants[edit source | edit]
⊟Expression vector[edit source | edit]
⊟lacZ fusion[edit source | edit]
⊟GFP fusion[edit source | edit]
⊟two-hybrid system[edit source | edit]
⊟FLAG-tag construct[edit source | edit]
⊟Antibody[edit source | edit]
⊟Other Information[edit source | edit]
You are kindly invited to share additional interesting facts.
⊟Literature[edit source | edit]
⊟References[edit source | edit]
⊟Relevant publications[edit source | edit]