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NCBI: 06-JUL-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_2586 [new locus tag: NWMN_RS14830 ]
  • pan locus tag?: SAUPAN006445000
  • symbol: drp35
  • pan gene symbol?: drp35
  • synonym:
  • product: Drp35

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_2586 [new locus tag: NWMN_RS14830 ]
  • symbol: drp35
  • product: Drp35
  • replicon: chromosome
  • strand: -
  • coordinates: 2853794..2854765
  • length: 972
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGTCACAACAAGATTTACCTACATTATTTTATAGCGGGAAGTCCAATAGTGCTGTTCCA
    ATTATATCTGAAAGTGAATTACAAACAATTACAGCTGAACCATGGCTTGAAATTTCCAAA
    AAAGGATTGCAACTAGAAGGATTGAACTTTGATCGGCAGGGACAACTCTTTTTATTGGAT
    GTATTCGAAGGCAATATTTTCAAAATCAATCCTGAAACGAAGGAAATCAAACGACCTTTT
    GTAAGTCACAAAGCGAATCCTGCAGCAATCAAAATACATAAAGATGGCCGATTATTCGTT
    TGTTATTTAGGAGATTTTAAATCTACAGGAGGCATTTTTGCAGCTACAGAAAATGGTGAC
    AACTTACAAGATATTATTGAAGATCTTTCAACAGCATATTGTATTGATGACATGGTATTT
    GATTCTAAAGGTGGATTTTATTTTACAGATTTTAGAGGATACTCTACCAATCCACTAGGA
    GGCGTTTATTATGTTTCGCCGGACTTTAGAACAGTGACGCCTATCATTCAAAATATTAGC
    GTAGCAAATGGTATTGCTTTAAGTACAGATGAAAAAGTACTATGGGTAACAGAAACAACA
    GCCAATCGATTACATCGCATTGCACTTGAAGATGATGGTGTGACGATACAACCATTTGGA
    GCTACCATACCGTACTATTTTACAGGTCATGAAGGACCAGACTCATGTTGTATTGATAGT
    GACGATAATTTATACGTAGCAATGTATGGTCAAGGTCGAGTGTTAGTTTTTAATAAAAGG
    GGTTATCCAATAGGACAAATATTGATACCAGGCCGAGATGAAGGGCATATGTTACGTTCT
    ACTCATCCGCAATTTATACCTGGAACAAATCAACTCATCATTTGTTCCAATGATATAGAA
    ATGGGCGGAGGATCTATGCTTTATACAGTTAATGGCTTTGCAAAAGGTCATCAAAGTTTT
    CAGTTTCAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    972

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_2586 [new locus tag: NWMN_RS14830 ]
  • symbol: Drp35
  • description: Drp35
  • length: 323
  • theoretical pI: 4.71521
  • theoretical MW: 35832.2
  • GRAVY: -0.19257

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
  • TheSEED:  
    Lactonase Drp35 (EC 3.1.1.-) 
  • PFAM:
    Beta_propeller (CL0186) SGL; SMP-30/Gluconolaconase/LRE-like region (PF08450; HMM-score: 102.2)
    Arylesterase; Arylesterase (PF01731; HMM-score: 28.9)
    Str_synth; Strictosidine synthase (PF03088; HMM-score: 27.7)
    NHL; NHL repeat (PF01436; HMM-score: 23)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 10
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.152
    • Ymax_pos: 33
    • Cmax: 0.145
    • Cmax_pos: 33
    • Smax: 0.225
    • Smax_pos: 2
    • Smean: 0.138
    • D: 0.146
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MSQQDLPTLFYSGKSNSAVPIISESELQTITAEPWLEISKKGLQLEGLNFDRQGQLFLLDVFEGNIFKINPETKEIKRPFVSHKANPAAIKIHKDGRLFVCYLGDFKSTGGIFAATENGDNLQDIIEDLSTAYCIDDMVFDSKGGFYFTDFRGYSTNPLGGVYYVSPDFRTVTPIIQNISVANGIALSTDEKVLWVTETTANRLHRIALEDDGVTIQPFGATIPYYFTGHEGPDSCCIDSDDNLYVAMYGQGRVLVFNKRGYPIGQILIPGRDEGHMLRSTHPQFIPGTNQLIICSNDIEMGGGSMLYTVNGFAKGHQSFQFQ

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • drp35 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator: CcpA
    CcpA (TF) important in Carbon catabolismRegPrecise

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]