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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS04945 [old locus tag: NWMN_0883 ]
  • pan locus tag?: SAUPAN003187000
  • symbol: NWMN_RS04945
  • pan gene symbol?:
  • synonym:
  • product: alanine:cation symporter family protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_RS04945 [old locus tag: NWMN_0883 ]
  • symbol: NWMN_RS04945
  • product: alanine:cation symporter family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 979207..980775
  • length: 1569
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_009641 (979207..980775) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
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    481
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    721
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    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGATTGAAAAATTAGTAACCTTTTTAAATGAGGTTGTTTGGAGTAAGCCATTAGTTTAT
    GGTTTGCTAATTACTGGTGTGCTATTTACATTGCGTATGCGATTTTTTCAAGTTAGACAT
    TTTAAAGAAATGATTCGATTAATGTTTCAAGGAGAGAAGTCTCCTAATGGTATTTCAAGT
    TTTCAAGCGATAGCCATGTCTTTAGCAGGCAGGGTTGGTACAGGTAATATTGTCGGTGTA
    TCTACTGCAATATTTATAGGAGGACCTGGTGCAGTATTTTGGATGTGGATTACTGCGTTT
    TTAGGTGCAAGTAGTGCTTTTATTGAATCTACACTTGGTCAAATATTCAAGAGAGTTGAA
    AATAATGAATACCGTGGTGGACCAGCGTATTATATTGAATATGGTATTGGTGGTAAATTT
    GGTAAAATTTACGGAATTATCTTTGCTATTGTTACGATTATCTCAGTAGGTCTATTGCTT
    CCTGGTGTGCAATCTAACGCTATAGCAAGTTCTATGCATAATGCGATTCATGTTCCACAA
    TGGTTAATGGGTGGTATTGTTGTAGTTATTTTGGGATTAATTATTTTTGGTGGTGTACGT
    AGTATTGCCAATGTTGCAACAGCCGTTGTACCATTTATGGCAATTATTTACATACTGATG
    GCTGTCATTATCATTTGTATCAATATACAAGAAGTGCCAGCGTTATTTGCATTAATTTTC
    AAATCAGCATTTGGATTACAATCTGCTTTTGGTGGTATCGTTGGCGCAATGATAGAGATT
    GGTGTTAAACGTGGATTATATTCAAATGAGGCTGGTCAAGGTACAGGTCCACACGCAGCA
    GCGGCAGCAGAAGTATCACATCCAAGTAAACAAGGTCTAGTACAAGCATTTTCAGTTTAT
    ATTGATACATTATTTGTATGTACTGCAACTGCTCTGATTATACTTATTTCTGGTACATAT
    AATGTGACTGATGGTACGGTTAATGCGAATGGCACACCGCATTTAATTAAAGATGGCGGT
    ATTTATGTTGAAAATGCAACAGGTAAAGATTATTCAGGTACTGCGATGTATGCACAAGCC
    GGCATTGATAAAGCGTTCCATGGCAGTGGTTATCAATTTGATCCTACTTTCTCTGGCGTA
    GGTTCGTACTTTATTGCATTTGCTTTATTCTTCTTTGCATTTACTACAATTTTGTCGTAC
    TACTACATTACAGAAACAAATGTTGCTTATTTAACGCGTAATCAAAATAATCAAGTTTCA
    TCGATATTTATTAATATTGCTCGTGTGATTATTTTGTTCGCTACATTTTACGGTGCAGTT
    AAAACAGCTGATGTAGCATGGGCATTCGGTGATTTAGGTGTAGGTCTAATGGCTTGGTTA
    AATATCATTGCGATTTGGATTTTACATAAGCCTGCCGTAAATGCTTTAAAAGATTATGAA
    ATTCAAAAGAAACGTTTAGGCAACGGTTATAATGCAGTTTATCAACCTGATCCGAATAAA
    TTACCTAATGCTGTCTTTTGGTTGAAGACGTATCCAGAACGTTTAAAACAAGCACGTGCC
    AAAAAGTAA
    60
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    1260
    1320
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    1560
    1569

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_RS04945 [old locus tag: NWMN_0883 ]
  • symbol: NWMN_RS04945
  • description: alanine:cation symporter family protein
  • length: 522
  • theoretical pI: 9.6768
  • theoretical MW: 56631.8
  • GRAVY: 0.527778

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    amino acid carrier protein (TIGR00835; HMM-score: 465.4)
  • TheSEED:
  • PFAM:
    APC (CL0062) Na_Ala_symp; Sodium:alanine symporter family (PF01235; HMM-score: 501.4)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 9
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.103
    • Ymax_pos: 16
    • Cmax: 0.113
    • Cmax_pos: 38
    • Smax: 0.131
    • Smax_pos: 11
    • Smean: 0.099
    • D: 0.101
  • predicted transmembrane helices (TMHMM): 10

Accession numbers[edit source | edit]

  • GI: 446492845 NCBI
  • RefSeq: WP_000570699 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MIEKLVTFLNEVVWSKPLVYGLLITGVLFTLRMRFFQVRHFKEMIRLMFQGEKSPNGISSFQAIAMSLAGRVGTGNIVGVSTAIFIGGPGAVFWMWITAFLGASSAFIESTLGQIFKRVENNEYRGGPAYYIEYGIGGKFGKIYGIIFAIVTIISVGLLLPGVQSNAIASSMHNAIHVPQWLMGGIVVVILGLIIFGGVRSIANVATAVVPFMAIIYILMAVIIICINIQEVPALFALIFKSAFGLQSAFGGIVGAMIEIGVKRGLYSNEAGQGTGPHAAAAAEVSHPSKQGLVQAFSVYIDTLFVCTATALIILISGTYNVTDGTVNANGTPHLIKDGGIYVENATGKDYSGTAMYAQAGIDKAFHGSGYQFDPTFSGVGSYFIAFALFFFAFTTILSYYYITETNVAYLTRNQNNQVSSIFINIARVIILFATFYGAVKTADVAWAFGDLGVGLMAWLNIIAIWILHKPAVNALKDYEIQKKRLGNGYNAVYQPDPNKLPNAVFWLKTYPERLKQARAKK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • NWMN_RS04945 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]