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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS06005 [old locus tag: NWMN_1064 ]
  • pan locus tag?: SAUPAN003391000
  • symbol: NWMN_RS06005
  • pan gene symbol?:
  • synonym:
  • product: non-canonical purine NTP pyrophosphatase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_RS06005 [old locus tag: NWMN_1064 ]
  • symbol: NWMN_RS06005
  • product: non-canonical purine NTP pyrophosphatase
  • replicon: chromosome
  • strand: +
  • coordinates: 1168817..1169404
  • length: 588
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_009641 (1168817..1169404) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
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    541
    ATGAAAGAGATTGTTATTGCATCGAATAATCAAGGGAAAATAAATGACTTTAAAGTAATA
    TTTCCAGATTACCACGTAATAGGTATTTCAGAACTAATACCAGATTTTGATGTGGAAGAA
    ACAGGATCAACATTTGAAGAAAATGCTATATTAAAATCAGAAGCTGCTGCAAAAGCATTG
    AATAAAACGGTCATAGCTGATGACAGTGGACTAGAAGTTTTTGCATTAAATGGTGAGCCA
    GGTATATACTCTGCACGTTATGCTGGTGAAAATAAAAGCGATGAAGCAAATATTGAAAAA
    TTATTAAATAAGCTTGGTAATACAACTGATCGTCGTGCGCAATTTGTTTGTGTCATAAGT
    ATGAGTGGCCCTGATATGGAAACAAAAGTATTTAAAGGTACTGTTTCAGGTGAAATTGCA
    GATGGAAAATATGGCGAAAATGGTTTCGGATATGATCCGATATTTTATGTACCGAAATTA
    GATAAAACCATGGCTCAACTTTCAAAAGAACAAAAAGGGCAAATTAGTCATAGACGAAAT
    GCGATTAATTTACTTCAAGCTTTTCTTGAAGGTGATAAAAATGTCTAA
    60
    120
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    360
    420
    480
    540
    588

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_RS06005 [old locus tag: NWMN_1064 ]
  • symbol: NWMN_RS06005
  • description: non-canonical purine NTP pyrophosphatase
  • length: 195
  • theoretical pI: 4.62754
  • theoretical MW: 21403
  • GRAVY: -0.36359

Function[edit source | edit]

  • reaction:
    EC 3.6.1.19?  ExPASy
    Nucleoside-triphosphate diphosphataseA nucleoside triphosphate + H2O = a nucleotide + diphosphate
  • TIGRFAM:
    Genetic information processingDNA metabolismDNA replication, recombination, and repairnon-canonical purine NTP pyrophosphatase, RdgB/HAM1 family (TIGR00042; EC 3.6.1.-; HMM-score: 203.2)
  • TheSEED:
  • PFAM:
    Maf (CL0269) Ham1p_like; Ham1 family (PF01725; HMM-score: 188.1)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors: Mg2+, Mn2+
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.104
    • Ymax_pos: 67
    • Cmax: 0.122
    • Cmax_pos: 67
    • Smax: 0.12
    • Smax_pos: 38
    • Smean: 0.081
    • D: 0.095
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446581971 NCBI
  • RefSeq: WP_000659317 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGSTFEENAILKSEAAAKALNKTVIADDSGLEVFALNGEPGIYSARYAGENKSDEANIEKLLNKLGNTTDRRAQFVCVISMSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKLDKTMAQLSKEQKGQISHRRNAINLLQAFLEGDKNV

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • NWMN_RS06005 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]