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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS07520 [old locus tag: NWMN_1334 ]
  • pan locus tag?: SAUPAN003854000
  • symbol: NWMN_RS07520
  • pan gene symbol?: msrB
  • synonym:
  • product: peptide-methionine (R)-S-oxide reductase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_RS07520 [old locus tag: NWMN_1334 ]
  • symbol: NWMN_RS07520
  • product: peptide-methionine (R)-S-oxide reductase
  • replicon: chromosome
  • strand: -
  • coordinates: 1468072..1468500
  • length: 429
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_009641 (1468072..1468500) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGCTTAAAAAAGATAAAAGTGAACTAACAGATATAGAATATATTGTTACACAAGAAAAC
    GGCACTGAACCACCATTTATGAATGAATATTGGAATCATTTTGCTAAAGGAATTTATGTA
    GATAAAATTTCTGGTAAACCTTTATTTACATCTGAAGAAAAGTTTCATTCTGAATGTGGA
    TGGCCTAGCTTTTCCAAAGCGCTTGATGACGATGAAATTATAGAATTAGTCGACAAATCA
    TTTGGTATGTTGAGAACTGAAGTGCGTTCAGAAGAATCAAATAGTCATTTAGGACATGTC
    TTTAATGATGGACCTAAAGAAAGTGGCGGCTTAAGATACTGTATCAATTCCGCTGCAATT
    CAATTTATTCCATATGAAAAGTTAGAAGAATTGGGTTATGGCGATTTAATATCACATTTT
    GATAAGTAG
    60
    120
    180
    240
    300
    360
    420
    429

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_RS07520 [old locus tag: NWMN_1334 ]
  • symbol: NWMN_RS07520
  • description: peptide-methionine (R)-S-oxide reductase
  • length: 142
  • theoretical pI: 4.49255
  • theoretical MW: 16277.1
  • GRAVY: -0.601408

Function[edit source | edit]

  • reaction:
    EC 1.8.4.12?  ExPASy
    Peptide-methionine (R)-S-oxide reductasePeptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin
    EC 1.8.4.11?  ExPASy
    Peptide-methionine (S)-S-oxide reductasePeptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxinL-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin
  • TIGRFAM:
    Cellular processesCellular processesAdaptations to atypical conditionsmethionine-R-sulfoxide reductase (TIGR00357; EC 1.8.4.-; HMM-score: 191.5)
    Genetic information processingProtein fateProtein modification and repairmethionine-R-sulfoxide reductase (TIGR00357; EC 1.8.4.-; HMM-score: 191.5)
  • TheSEED:
  • PFAM:
    Beta-tent (CL0080) SelR; SelR domain (PF01641; HMM-score: 158.1)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.105
    • Ymax_pos: 30
    • Cmax: 0.108
    • Cmax_pos: 36
    • Smax: 0.144
    • Smax_pos: 2
    • Smean: 0.094
    • D: 0.101
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446836059 NCBI
  • RefSeq: WP_000913315 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MLKKDKSELTDIEYIVTQENGTEPPFMNEYWNHFAKGIYVDKISGKPLFTSEEKFHSECGWPSFSKALDDDEIIELVDKSFGMLRTEVRSEESNSHLGHVFNDGPKESGGLRYCINSAAIQFIPYEKLEELGYGDLISHFDK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • NWMN_RS07520 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]