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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS08435 [old locus tag: NWMN_1499 ]
  • pan locus tag?: SAUPAN004183000
  • symbol: NWMN_RS08435
  • pan gene symbol?:
  • synonym:
  • product: ribosome biogenesis GTPase YqeH

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_RS08435 [old locus tag: NWMN_1499 ]
  • symbol: NWMN_RS08435
  • product: ribosome biogenesis GTPase YqeH
  • replicon: chromosome
  • strand: -
  • coordinates: 1665050..1666150
  • length: 1101
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_009641 (1665050..1666150) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    TTGTCTGACATTTTAAAATGTATCGGTTGTGGTGCGCCACTTCAATCTGAAGATAAAAAT
    AAACCTGGTTTTGTACCAGAGCATAATATGTTTCGTGATGACGTGATTTGCAGACGTTGT
    TTCCGCTTGAAAAATTATAACGAAGTTCAAGATGTAGGATTAGAAAGTGAAGACTTTTTA
    AAATTATTATCAGGACTTGCGGATAAAAAGGGTATTGTCGTCAATGTCGTGGATGTATTT
    GACTTTGAAGGATCATTTATTAATGCAGTTAAACGTATTGTCGGAAACAAAAAAATCATT
    TTAGCAGCAAATAAATTGGATTTATTGCCGAAACAAATTAATAAACGTCGAGTTAAAGAA
    TGGTTAAAACGAACAGCAAGAAAATATGGTTTGGAAGCTGACGATGTCGTATTAATTTCA
    GCTGAAAAAGGCTGGGGCATAGACGACTTATTATCATCAATTGCGAATATTCGAGAAAAT
    GAAGATGTGTATATTGTAGGGACAACGAATGTTGGGAAATCTACATTGATTAATAAACTG
    ATTGAAGCTAGTGTTGGTGAAAAAGATGTAGTAACAACTTCAAGATTCCCTGGAACAACT
    TTAGATATGATAGATATTCCTTTAGATGAAACATCATTTATGTATGATACACCAGGTATT
    ATTCAAGATCACCAAATGACGCATTTAGTTAGTGAAAAAGAATTGAAAATTATTATGCCT
    AAGAAAGAAATAAAACAACGCGTATATCAATTAAATGAGGCGCAGACATTATTCTTCGGC
    GGTCTAGCGCGCATAGATTATGTATCAGGTGGTAAACGTCCGTTAGTTTGTTTCTTTTCT
    AATGACTTGAATATACATCGTACTAAAACGGAGAAGGCTAATGATTTATGGCGTAATCAA
    CTTGGCGATTTATTAACGCCACCTGGAAATCCACAAAATTTTGATCTTAATGAGGTAAAG
    GCTGTTAGACTTGAAACAGGCAAAGAGAAACGCGATGTTATGATCTCTGGTCTAGGCTTT
    ATAACTATAGGACCAGGGGCTAAAGTAATCGTTCGTGTTCCTAAAAATGTTGATGTTGTA
    TTAAGAAATTCTATTTTATAA
    60
    120
    180
    240
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    360
    420
    480
    540
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    660
    720
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    840
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    960
    1020
    1080
    1101

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_RS08435 [old locus tag: NWMN_1499 ]
  • symbol: NWMN_RS08435
  • description: ribosome biogenesis GTPase YqeH
  • length: 366
  • theoretical pI: 8.44888
  • theoretical MW: 41086.3
  • GRAVY: -0.22459

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Genetic information processingProtein synthesisOtherribosome biogenesis GTPase YqeH (TIGR03597; HMM-score: 486.9)
    Genetic information processingProtein synthesisOtherribosome-associated GTPase EngA (TIGR03594; HMM-score: 60.6)
    Genetic information processingProtein synthesisOtherribosome biogenesis GTP-binding protein YlqF (TIGR03596; HMM-score: 52.5)
    Genetic information processingProtein synthesisOtherribosome biogenesis GTP-binding protein YsxC (TIGR03598; HMM-score: 40)
    Unknown functionGeneralGTP-binding protein HflX (TIGR03156; HMM-score: 37.5)
    Unknown functionGeneralsmall GTP-binding protein domain (TIGR00231; HMM-score: 37.4)
    Genetic information processingProtein synthesisOtherGTP-binding protein Era (TIGR00436; HMM-score: 33.2)
    Genetic information processingProtein synthesisOtherObg family GTPase CgtA (TIGR02729; HMM-score: 32.9)
    Genetic information processingProtein fateProtein modification and repair[FeFe] hydrogenase H-cluster maturation GTPase HydF (TIGR03918; HMM-score: 30.5)
    Genetic information processingProtein synthesisTranslation factorsribosome small subunit-dependent GTPase A (TIGR00157; EC 3.6.-.-; HMM-score: 28.5)
    Genetic information processingProtein synthesistRNA and rRNA base modificationtRNA modification GTPase TrmE (TIGR00450; EC 3.6.-.-; HMM-score: 28.2)
    MetabolismTransport and binding proteinsCations and iron carrying compoundsferrous iron transport protein B (TIGR00437; HMM-score: 22.9)
    Genetic information processingProtein synthesisTranslation factorsselenocysteine-specific translation elongation factor (TIGR00475; HMM-score: 21.9)
    Unknown functionGeneralelongation factor 4 (TIGR01393; EC 3.6.5.-; HMM-score: 18.5)
    translation initiation factor 2, gamma subunit (TIGR03680; HMM-score: 18.4)
    MetabolismEnergy metabolismAmino acids and aminesethanolamine utilization protein, EutP (TIGR02528; HMM-score: 15.3)
    Genetic information processingProtein synthesisTranslation factorstranslation initiation factor IF-2 (TIGR00487; HMM-score: 14.2)
    Unknown functionGeneralGTP-binding protein YchF (TIGR00092; HMM-score: 13.9)
    MetabolismTransport and binding proteinsUnknown substrateenergy-coupling factor transporter ATPase (TIGR04521; EC 3.6.3.-; HMM-score: 11.7)
    Genetic information processingProtein fateProtein and peptide secretion and traffickingtype VII secretion protein EccCb (TIGR03925; HMM-score: 11)
  • TheSEED:
  • PFAM:
    P-loop_NTPase (CL0023) MMR_HSR1; 50S ribosome-binding GTPase (PF01926; HMM-score: 54.2)
    RsgA_GTPase; RsgA GTPase (PF03193; HMM-score: 39.8)
    FeoB_N; Ferrous iron transport protein B (PF02421; HMM-score: 34.6)
    GTP_EFTU; Elongation factor Tu GTP binding domain (PF00009; HMM-score: 27.3)
    Roc; Ras of Complex, Roc, domain of DAPkinase (PF08477; HMM-score: 21.9)
    Ras; Ras family (PF00071; HMM-score: 19.6)
    Dynamin_N; Dynamin family (PF00350; HMM-score: 18.8)
    ABC_tran; ABC transporter (PF00005; HMM-score: 17.2)
    no clan definedMMR_HSR1_Xtn; C-terminal region of MMR_HSR1 domain (PF16897; HMM-score: 17)
    P-loop_NTPase (CL0023) ATPase_2; ATPase domain predominantly from Archaea (PF01637; HMM-score: 16.3)
    RNA_helicase; RNA helicase (PF00910; HMM-score: 14.4)
    ArgK; ArgK protein (PF03308; HMM-score: 13.4)
    AAA_18; AAA domain (PF13238; HMM-score: 12.8)
    PduV-EutP; Ethanolamine utilisation - propanediol utilisation (PF10662; HMM-score: 12.4)
    AAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 12.3)
    cobW; CobW/HypB/UreG, nucleotide-binding domain (PF02492; HMM-score: 12.2)
    no clan definedSwi5; Swi5 (PF07061; HMM-score: 12.2)
    P-loop_NTPase (CL0023) FtsK_SpoIIIE; FtsK/SpoIIIE family (PF01580; HMM-score: 12.1)
    Arf; ADP-ribosylation factor family (PF00025; HMM-score: 8.7)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.131
    • Ymax_pos: 22
    • Cmax: 0.106
    • Cmax_pos: 22
    • Smax: 0.201
    • Smax_pos: 15
    • Smean: 0.134
    • D: 0.132
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 447202885 NCBI
  • RefSeq: WP_001280141 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MSDILKCIGCGAPLQSEDKNKPGFVPEHNMFRDDVICRRCFRLKNYNEVQDVGLESEDFLKLLSGLADKKGIVVNVVDVFDFEGSFINAVKRIVGNKKIILAANKLDLLPKQINKRRVKEWLKRTARKYGLEADDVVLISAEKGWGIDDLLSSIANIRENEDVYIVGTTNVGKSTLINKLIEASVGEKDVVTTSRFPGTTLDMIDIPLDETSFMYDTPGIIQDHQMTHLVSEKELKIIMPKKEIKQRVYQLNEAQTLFFGGLARIDYVSGGKRPLVCFFSNDLNIHRTKTEKANDLWRNQLGDLLTPPGNPQNFDLNEVKAVRLETGKEKRDVMISGLGFITIGPGAKVIVRVPKNVDVVLRNSIL

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • NWMN_RS08435 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]