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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS10080 [old locus tag: NWMN_1762 ]
  • pan locus tag?: SAUPAN004853000
  • symbol: NWMN_RS10080
  • pan gene symbol?:
  • synonym:
  • product: membrane protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS10080 [old locus tag: NWMN_1762 ]
  • symbol: NWMN_RS10080
  • product: membrane protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1974155..1974991
  • length: 837
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_009641 (1974155..1974991) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_1762

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGCTAGATAATATTATTTTATATTTTAAAAACTTACCGCATACTAAAAGGTATGTAACA
    GAACGTTTAAAACAAAGTTGGAAAAGTTTTCTAATCGTATTAGCTGCATGTTTAATACTT
    ATTATTGCAAGTGAAACGCTATTTTCCTTTAGTCATTTGACCGATGTTAAAGAGGTGAGA
    TGGTTATTTAGAATCATTGTATTGATTGTTTTTGCGGTAGTGATGTTCACAATTTATATC
    TCTTATCATCATTATATGAATGACTTTTTAGTTACTAAGTTATTTAATATTTCCGCAGCG
    ACGCCAGTAGTTATTATGTCTATTTTAAGTTTTATTATGCTAGTCATTTTGACGATGATT
    AGTGCATTGGTTAAACCAGTAAACTTCGAAACATCATATATAGCGCTATTCTATTTTATT
    GTGATGGCAACTATTTTTGTAGGATTAATATCCGTTACTTTTGGTCTTATTCGACTGTTA
    ACTGAAAAAATAAATATCATATTTTATGGGGTTTGTGTATTGTGTTTCTTATTGTTACCA
    ATTATTTTCATACCAAATCCAAATCATGTATTTATCAATCACATCCTAATGCTAAATCCA
    ATGTATTACATTGTTAATGGTATAGCACAATCTATCATATTTGGTATATCAAGTATGGAA
    AACATTCCATATCATTTTTACTTTATTTTATTCTTATGTTTAATAGCTGCAGTAAATTTC
    GTATTAGCAAGGTATACGACACACGCAATTTATAATAAAACATCTAAAGTGACACAAACT
    GATAATCAACAGGATGTTTCAAATGATAGTACAGACGAGGCGGATACTTCTTCATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    837

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS10080 [old locus tag: NWMN_1762 ]
  • symbol: NWMN_RS10080
  • description: membrane protein
  • length: 278
  • theoretical pI: 7.9856
  • theoretical MW: 31955
  • GRAVY: 0.889928

Function[edit | edit source]

  • TIGRFAM:
    TIGR03943 family protein (TIGR03943; HMM-score: 3.4)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    no clan defined DUF2615; Protein of unknown function (DUF2615) (PF11027; HMM-score: 8.4)
    ABC-2 (CL0181) ABC2_membrane; ABC-2 type transporter (PF01061; HMM-score: 7.8)
    no clan defined DUF4131; Domain of unknown function (DUF4131) (PF13567; HMM-score: 7.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.013138
    • TAT(Tat/SPI): 0.000387
    • LIPO(Sec/SPII): 0.078075
  • predicted transmembrane helices (TMHMM): 7

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MLDNIILYFKNLPHTKRYVTERLKQSWKSFLIVLAACLILIIASETLFSFSHLTDVKEVRWLFRIIVLIVFAVVMFTIYISYHHYMNDFLVTKLFNISAATPVVIMSILSFIMLVILTMISALVKPVNFETSYIALFYFIVMATIFVGLISVTFGLIRLLTEKINIIFYGVCVLCFLLLPIIFIPNPNHVFINHILMLNPMYYIVNGIAQSIIFGISSMENIPYHFYFILFLCLIAAVNFVLARYTTHAIYNKTSKVTQTDNQQDVSNDSTDEADTSS

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]