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NCBI: 26-AUG-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA0091 [new locus tag: SA_RS00615 ]
  • pan locus tag?: SAUPAN000858000
  • symbol: plc
  • pan gene symbol?: plc
  • synonym:
  • product: 1-phosphatidylinositol phosphodiesterase precurosr

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA0091 [new locus tag: SA_RS00615 ]
  • symbol: plc
  • product: 1-phosphatidylinositol phosphodiesterase precurosr
  • replicon: chromosome
  • strand: +
  • coordinates: 102646..103632
  • length: 987
  • essential: no DEG other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAAAAAGTGTATTAAGACTTTGTTTTTAAGTATCATTTTAGTAGTGATGGGTGGTTGG
    TATCATTCAGCACATGCGTCAGATTCGTTGAGTAAAAGTCCAGAAAATTGGATGAGTAAA
    CTTGATGAAAGCAAACATTTAACTGAGATTAATATGCCAGGCTCACATGATAGTGGCTCA
    TTCACTTTAACTGATCCGGTAAAATCGGTTTGGGCAAAGACTCAAGGCAAAGATTACCTT
    ACTCAAATGAAGTCGGGAGTCAGGTTTTTTGATATTAGAGGTAGAGCAAGTGCTGATAAT
    ATGATTTCAGTTCATCACGGCATGGTTTATTTGCATCATGAACTAGGAAAATTTTTAGAT
    GATGCTAAATATTACTTGAGTGCTTATCCAAACGAAACAATTGTGATGTCTATGAAAAAG
    GACTACGATAGCGATTCTAAAGTTACGAAGACATTTGAAGAGATTTTTAGAGAATATTAT
    TATAATAACCCGCAATATCAGAATCTTTTTTACACAGGAAGTAATGCGAATCCTACTTTA
    AAAGAAACGAAAGGTAAAATTGTCCTATTCAATAGAATGGGGGGTACATACATAAAGAGT
    GGTTATGGTGCTGACACGTCAGGTATTCAATGGGCAGACAATGCGACATTTGAAACGAAA
    ATTAATAATGGTAGCTTAAATTTAAAAGTACAAGATGAGTATAAAGATTACTATGATAAA
    AAAGTTGAAGCTGTTAAAAATTTATTGGCTAAAGCTAAAACGGATAGTAACAAAGACAAT
    GTATATGTGAATTTCTTGAGTGTAGCGTCTGGAGGTAGCGCATTTAATAGTACTTATAAC
    TATGCATCACATATAAATCCTGAAATTGCAAAAACGATTAAAGAAAACGGGAAAGCTAGA
    ACTGGTTGGCTGATTGTTGACTATGCAGGATATCCGTGGCCTGGATATGATGATATCGTA
    AGTGAAATTATAGATAGTAATAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    987

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA0091 [new locus tag: SA_RS00615 ]
  • symbol: Plc
  • description: 1-phosphatidylinositol phosphodiesterase precurosr
  • length: 328
  • theoretical pI: 8.2827
  • theoretical MW: 37087.5
  • GRAVY: -0.56311

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
  • TheSEED:  
    Phages, Prophages, Transposable elements, PlasmidsPathogenicity islandsListeria Pathogenicity Island LIPI-1 extended Phosphatidylinositol-specific phospholipase C (EC 4.6.1.13) 
  • PFAM:
    PLC (CL0384) PI-PLC-X; Phosphatidylinositol-specific phospholipase C, X domain (PF00388; HMM-score: 64.4)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.02
    • Extracellular Score: 9.98
    • Internal Helices: 0
  • LocateP: N-terminally anchored (No CS)
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: 1
    • N-terminally Anchored Score: 5
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: Signal peptide length 27 aa
    • Ymax: 0.553
    • Ymax_pos: 27
    • Cmax: 0.413
    • Cmax_pos: 27
    • Smax: 0.889
    • Smax_pos: 18
    • Smean: 0.756
    • D: 0.633
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit source | edit]

  • GI: 15925799 NCBI
  • RefSeq: NP_373332 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MKKCIKTLFLSIILVVMGGWYHSAHASDSLSKSPENWMSKLDESKHLTEINMPGSHDSGSFTLTDPVKSVWAKTQGKDYLTQMKSGVRFFDIRGRASADNMISVHHGMVYLHHELGKFLDDAKYYLSAYPNETIVMSMKKDYDSDSKVTKTFEEIFREYYYNNPQYQNLFYTGSNANPTLKETKGKIVLFNRMGGTYIKSGYGADTSGIQWADNATFETKINNGSLNLKVQDEYKDYYDKKVEAVKNLLAKAKTDSNKDNVYVNFLSVASGGSAFNSTYNYASHINPEIAKTIKENGKARTGWLIVDYAGYPWPGYDDIVSEIIDSNK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]