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NCBI: 26-AUG-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA0592 [new locus tag: SA_RS03405 ]
  • pan locus tag?: SAUPAN002512000
  • symbol: tagA
  • pan gene symbol?: tagA
  • synonym:
  • product: teichoic acid biosynthesis protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA0592 [new locus tag: SA_RS03405 ]
  • symbol: tagA
  • product: teichoic acid biosynthesis protein
  • replicon: chromosome
  • strand: +
  • coordinates: 685072..685836
  • length: 765
  • essential: no DEG other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGACTGTTGAAGAAAGATCCAATACAGCCAAAGTTGACATTTTAGGGGTCGATTTTGAT
    AATACAACAATGTTGCAAATGGTTGAAAATATTAAAACCTTTTTTGCAAATCAATCAACG
    AATAATCTTTTTATAGTAACAGCCAACCCTGAAATAGTGAATTACGCGACGACACATCAA
    GCGTATTTAGAGTTAATAAATCAAGCGAGCTATATTGTTGCTGATGGGACAGGAGTAGTC
    AAAGCTTCGCATCGTTTAAAGCAACCTCTAGCGCATCGTATACCTGGTATTGAGTTGATG
    GATGAATGTTTGAAAATTGCTCATGTAAATCATCAAAAAGTATTTTTGCTAGGGGCAACT
    AATGAAGTTGTAGAAGCGGCACAATATGCATTGCAACAAAGATATCCAAACATATCGTTT
    GCACATCATCACGGTTATATTGATTTAGAAGATGAGACAGTAGTAAAACGAATTAAACTG
    TTTAAACCTGATTACATATTTGTAGGTATGGGATTCCCTAAACAAGAAGAATGGATTATG
    ACACATGAAAACCAATTTGAATCTACAGTGATGATGGGCGTAGGTGGTTCTCTTGAAGTA
    TTTGCTGGGGCTAAAAAGAGAGCGCCTTATATATTTAGAAAATTAAACATTGAATGGATA
    TATAGAGCATTAATAGATTGGAAACGTATTGGTAGATTGAAGAGTATTCCAATATTTATG
    TATAAAATAGCCAAAGCAAAAAGAAAAATAAAAAAAGCGAAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    765

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA0592 [new locus tag: SA_RS03405 ]
  • symbol: TagA
  • description: teichoic acid biosynthesis protein
  • length: 254
  • theoretical pI: 9.77365
  • theoretical MW: 29132.7
  • GRAVY: -0.177953

Function[edit source | edit]

  • reaction:
    EC 2.4.1.187?  ExPASy
    N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferaseUDP-N-acetyl-alpha-D-mannosamine + N-acetyl-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol = UDP + N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
  • TIGRFAM:
    Cell structureCell envelopeBiosynthesis and degradation of surface polysaccharides and lipopolysaccharidesglycosyltransferase, WecB/TagA/CpsF family (TIGR00696; EC 2.4.1.-; HMM-score: 160.5)
  • TheSEED:  
    Cell Wall and CapsuleGram-Positive cell wall componentsTeichoic and lipoteichoic acids biosynthesis N-acetylmannosaminyltransferase (EC 2.4.1.187) 
  • PFAM:
    no clan definedGlyco_tran_WecB; Glycosyl transferase WecB/TagA/CpsF family (PF03808; HMM-score: 173.1)
    P-loop_NTPase (CL0023) AAA_34; P-loop containing NTP hydrolase pore-1 (PF13872; HMM-score: 11.2)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.153
    • Ymax_pos: 37
    • Cmax: 0.146
    • Cmax_pos: 37
    • Smax: 0.185
    • Smax_pos: 36
    • Smean: 0.106
    • D: 0.134
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MTVEERSNTAKVDILGVDFDNTTMLQMVENIKTFFANQSTNNLFIVTANPEIVNYATTHQAYLELINQASYIVADGTGVVKASHRLKQPLAHRIPGIELMDECLKIAHVNHQKVFLLGATNEVVEAAQYALQQRYPNISFAHHHGYIDLEDETVVKRIKLFKPDYIFVGMGFPKQEEWIMTHENQFESTVMMGVGGSLEVFAGAKKRAPYIFRKLNIEWIYRALIDWKRIGRLKSIPIFMYKIAKAKRKIKKAK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • tagA no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]