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NCBI: 26-AUG-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1221 [new locus tag: SA_RS06935 ]
  • pan locus tag?: SAUPAN003798000
  • symbol: SA1221
  • pan gene symbol?: pstS
  • synonym:
  • product: thioredoxine reductase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA1221 [new locus tag: SA_RS06935 ]
  • symbol: SA1221
  • product: thioredoxine reductase
  • replicon: chromosome
  • strand: -
  • coordinates: 1394073..1395056
  • length: 984
  • essential: no DEG other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAAAAAATGGCAATTTGTTGGTACTACAGCTTTAGGTGCAACACTATTATTAGGTGCT
    TGTGGTGGCGGTAATGGTGGCAGTGGTAATAGTGATTTAAAAGGGGAAGCTAAAGGTGAT
    GGCTCATCAACAGTAGCACCAATTGTGGAGAAATTAAATGAAAAATGGGCTCAAGATCAC
    TCGGATGCTAAAATCTCAGCAGGACAAGCTGGTACAGGTGCTGGTTTCCAAAAATTCATT
    GCAGGAGATATCGACTTCGCTGATGCTTCTAGACCAATTAAAGATGAAGAGAAGCAAAAA
    TTACAAGATAAGAATATCAAATACAAAGAATTTAAAATTGCGCAAGATGGTGTAACGGTT
    GCTGTAAATAAAGAAAATGATTTTGTAGATGAATTAGACAAACAGCAATTAAAAGCAATT
    TATTCTGGAAAAGCTAAAACATGGAAAGATGTTAATAGTAAATGGCCAGATAAAAAAATA
    AATGCTGTATCACCAAACTCAAGTCATGGTACTTATGACTTCTTCGAAAATGAAGTAATG
    AATAAAGAAGATATTAAAGCAGAAAAAAATGCTGATACAAATGCTATCGTTTCTTCTGTA
    ACGAAAAACAAAGAGGGAATCGGATACTTTGGATATAACTTCTACGTACAAAATAAAGAT
    AAATTAAAAGAAGTTAAAATCAAAGATGAAAATGGTAAAGCAACAGAGCCTACGAAAAAA
    ACAATTCAAGATAACTCTTATGCATTAAGTAGACCATTATTCATTTATGTAAATGAAAAA
    GCATTGAAAGATAATAAAGTAATGTCAGAATTTATCAAATTCGTCTTAGAAGATAAAGGT
    AAAGCAGCTGAAGAAGCTGGATATGTAGCAGCACCAGAGAAAACATACAAATCACAATTA
    GATGATTTAAAAGCATTTATTGATAAAAATCAAAAATCAGACGACAAGAAATCTGATGAT
    AAAAAGTCTGAAGACAAAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    984

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA1221 [new locus tag: SA_RS06935 ]
  • symbol: SA1221
  • description: thioredoxine reductase
  • length: 327
  • theoretical pI: 8.71151
  • theoretical MW: 36117.2
  • GRAVY: -0.870031

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismTransport and binding proteinsAnionsphosphate binding protein (TIGR02136; HMM-score: 344.1)
    MetabolismTransport and binding proteinsAnionsphosphate ABC transporter, phosphate-binding protein PstS (TIGR00975; HMM-score: 65)
    phosphate ABC transporter substrate-binding protein (TIGR04505; HMM-score: 50.1)
  • TheSEED:  
    Phosphorus MetabolismPhosphorus Metabolism - no subcategoryHigh affinity phosphate transporter and control of PHO regulon Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) 
    Phosphorus Metabolism - no subcategoryPhosphate metabolism Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) 
  • PFAM:
    PBP (CL0177) PBP_like_2; PBP superfamily domain (PF12849; HMM-score: 137.8)
    PBP_like; PBP superfamily domain (PF12727; HMM-score: 60.2)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 9.68
    • Cellwall Score: 0.17
    • Extracellular Score: 0.16
    • Internal Helix: 1
  • LocateP: Lipid anchored
    • Prediction by SwissProt Classification: Extracellular
    • Pathway Prediction: Sec-(SPII)
    • Intracellular Possibility: -0.33
    • Signal Peptide Possibility: 1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: LLLGACG
  • SignalP: no predicted signal peptide
    • Ymax: 0.269
    • Ymax_pos: 23
    • Cmax: 0.139
    • Cmax_pos: 40
    • Smax: 0.651
    • Smax_pos: 19
    • Smean: 0.54
    • D: 0.375
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MKKWQFVGTTALGATLLLGACGGGNGGSGNSDLKGEAKGDGSSTVAPIVEKLNEKWAQDHSDAKISAGQAGTGAGFQKFIAGDIDFADASRPIKDEEKQKLQDKNIKYKEFKIAQDGVTVAVNKENDFVDELDKQQLKAIYSGKAKTWKDVNSKWPDKKINAVSPNSSHGTYDFFENEVMNKEDIKAEKNADTNAIVSSVTKNKEGIGYFGYNFYVQNKDKLKEVKIKDENGKATEPTKKTIQDNSYALSRPLFIYVNEKALKDNKVMSEFIKFVLEDKGKAAEEAGYVAAPEKTYKSQLDDLKAFIDKNQKSDDKKSDDKKSEDKK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]