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NCBI: 10-JUN-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL0267 [new locus tag: SACOL_RS01355 ]
  • pan locus tag?: SAUPAN001168000
  • symbol: SACOL0267
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL0267 [new locus tag: SACOL_RS01355 ]
  • symbol: SACOL0267
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 305492..307015
  • length: 1524
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    ATGTCTAAAAAGTTAAAAATTATAATTCCTATTATTATTGTCTTACTATTAATAGGTGGA
    ATCGCATGGGGAGTTTATGCATTTTTTGCTAATACACCGAAAAATACATACCTAAAAAGT
    GAACAACAAACAGCAAAAATGTATAAAGATTATTTTAATGACCGTTTTGAAAATGAAGTG
    AAGTTCCAAGAAAAGATGAAAGATAATTCGTTTTTATCTTCATTAGAATTAAGCGCAGAT
    GCATCAGATGAAATTGTTAAAGGGCTTGGCATTCCTAAATCTGTTGTTAATGCATCGAAA
    ATTAAAATGTCATATGGACATGATCCTAAAAAAGAGAAATCAATGATTAATCTTGAACCA
    ACAATCGCAGACTCTGCATTAGGGAAATTCCAGTTAGCTGCAGATAAAGATAAGCATTAT
    TTCGAATCACCATTATTTAAAGGGAAATATAGTGTTAATAATTCTGATTTATTATCAACT
    TATTCAAAACTTACAGGTGAAGATGAAGAAACAGCAAAAGAAAATGGTATTACAAACCAA
    CAACTAAATTTAAATACTCTTTTTAATAATGCTCAAGCACAACAAAGTGACTACAGCAAA
    ATTGCCGAAAAATATTCCGAACTTATTGTCGACAAATTAGATGACGATAATTTTGATAAA
    GGTAAAAAAGAAGAAATTAAGGTTAATGGTGAAAAGTACAAAGTTAGACCTGTCACGTTA
    ACACTTAGCAGAGCTGACACTAAAAAAATTACATTAGCTGTATTAGAAGAAGCTAAAAAG
    GATAAAGACCTTAAAAAATTAATGGAAGAACAAGGTGCTAGAAAAGACTTTGAAAAAGAC
    ATCAAAAAAGCAATTGACGATGTCAAAGAAACTAAAAAGGATGAATTTGCTAAAATTCAA
    TCTAAAATTTATACCGAAAAACATACGATTGTAAAACGAGAAATTACTATTACAGACAAA
    GAAAATAATAAAACTAAAATCAAAGGTACTAATACTTTAGAAGACGATAAGTTAAAACTA
    GATTACGCACTTGATTTCGATCAAGATAAATACACGTATGCTGAAGCGAAATATACAATT
    AAAGGCGTATCTTCTAAAGAAAAAGATAATAAATATAATGATAAATACGAATTTGGTAAA
    AAGACAGAATATGATGAATCAAAAATCAAATTAGATAACCAAGAAAAAGTAGATGGCACA
    AAACGTCAAGATAAAGGTAAAATCACTGTCGCATTAGATAAATATAGCGACGAAAATGAA
    TTCACTTTTGAAAATAATATAGATTCTGACGTAAAAAATAACACTCAGAAATCTACGTTA
    AATATCGGCATCAAATATGCTGAAGAACCAATTAATTTCATTTTAAAATCTAGCACAAAA
    TTGAAAGCAGATATTGATTTTGATGATAGTGGTGCAAAAGATTTCAATAGTCTATCTTCA
    AAAGACCGTGAAAAACTTGAAAAAGAAATCGAAAAAAATGGCGGCAAAATGTTTGAATCA
    ATTTTAAAAAAGGCATCTAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1524

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL0267 [new locus tag: SACOL_RS01355 ]
  • symbol: SACOL0267
  • description: hypothetical protein
  • length: 507
  • theoretical pI: 8.69108
  • theoretical MW: 57977.1
  • GRAVY: -0.905917

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
  • TheSEED:  
    FIG01108182: hypothetical protein 
  • PFAM:
    BRCT-like (CL0459) PTCB-BRCT; twin BRCT domain (PF12738; HMM-score: 12.8)
    no clan definedOrthopox_F14; Orthopoxvirus F14 protein (PF06076; HMM-score: 12.5)
    SapC; SapC (PF07277; HMM-score: 9.9)
    DUF378; Domain of unknown function (DUF378) (PF04070; HMM-score: 9.4)
    DUF2746; Protein of unknown function (DUF2746) (PF10874; HMM-score: 9.3)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 3.33
    • Cellwall Score: 3.33
    • Extracellular Score: 3.33
    • Internal Helix: 1
  • LocateP: N-terminally anchored (No CS)
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: 0
    • N-terminally Anchored Score: 4
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.29
    • Ymax_pos: 28
    • Cmax: 0.255
    • Cmax_pos: 28
    • Smax: 0.606
    • Smax_pos: 7
    • Smean: 0.424
    • D: 0.342
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MSKKLKIIIPIIIVLLLIGGIAWGVYAFFANTPKNTYLKSEQQTAKMYKDYFNDRFENEVKFQEKMKDNSFLSSLELSADASDEIVKGLGIPKSVVNASKIKMSYGHDPKKEKSMINLEPTIADSALGKFQLAADKDKHYFESPLFKGKYSVNNSDLLSTYSKLTGEDEETAKENGITNQQLNLNTLFNNAQAQQSDYSKIAEKYSELIVDKLDDDNFDKGKKEEIKVNGEKYKVRPVTLTLSRADTKKITLAVLEEAKKDKDLKKLMEEQGARKDFEKDIKKAIDDVKETKKDEFAKIQSKIYTEKHTIVKREITITDKENNKTKIKGTNTLEDDKLKLDYALDFDQDKYTYAEAKYTIKGVSSKEKDNKYNDKYEFGKKTEYDESKIKLDNQEKVDGTKRQDKGKITVALDKYSDENEFTFENNIDSDVKNNTQKSTLNIGIKYAEEPINFILKSSTKLKADIDFDDSGAKDFNSLSSKDREKLEKEIEKNGGKMFESILKKASK

Experimental data[edit source | edit]

  • experimental localization: Signal peptide containing [1]

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

  1. Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int. J. Med. Microbiol.: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)

Relevant publications[edit source | edit]