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NCBI: 10-JUN-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL0737 [new locus tag: SACOL_RS03785 ]
  • pan locus tag?: SAUPAN002561000
  • symbol: SACOL0737
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL0737 [new locus tag: SACOL_RS03785 ]
  • symbol: SACOL0737
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 759913..760308
  • length: 396
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    ATGAAGAAATTAATCATCAGTATTATGGCGGTCATGCTATTTTTAACAGGTTGTGGTAAA
    AGTCAAGAGAAAGCCACTCTGGAAAAGGATATCGATAATTTACAAAAAGAAAATAAAGAA
    TTAAAAGACAAAAAAGAAAAGCTTCAACAAGAAAAAGAAAAATTAGCAGATAAGCAAAAA
    GACCTTGAAAAAGAAGTGAAAGATTTAAAACCTTCAAAAGAAGATAACAAGGATGATAAA
    AAAGACGAAGACAAAAATAAAGACAAAGATAAAGATAAAGAGGCATCACAAGATAAGCAA
    TCAAAAGATCAAACTAAGTCATCGGATAAAGATAATCACAAAAAGCCTACATCAGCAGAT
    AAAGATCAAAAAGCTAATGACAAACACCAATCATAA
    60
    120
    180
    240
    300
    360
    396

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL0737 [new locus tag: SACOL_RS03785 ]
  • symbol: SACOL0737
  • description: hypothetical protein
  • length: 131
  • theoretical pI: 9.36324
  • theoretical MW: 15188
  • GRAVY: -1.87863

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Cellular processesCellular processesSporulation and germinationtranscription factor, RsfA family (TIGR02894; HMM-score: 19.6)
    Signal transductionRegulatory functionsDNA interactionstranscription factor, RsfA family (TIGR02894; HMM-score: 19.6)
    Cellular processesCellular processesSporulation and germinationsporulation lipoprotein, YhcN/YlaJ family (TIGR02898; HMM-score: 19.4)
    Genetic information processingProtein fateProtein and peptide secretion and traffickingouter membrane assembly lipoprotein YfiO (TIGR03302; HMM-score: 16.7)
    SH3 domain protein (TIGR04211; HMM-score: 9.6)
    Cellular processesCellular processesCell divisioncell division protein ZipA (TIGR02205; HMM-score: 7.9)
    Cellular processesCellular processesCell divisionchromosome segregation protein SMC (TIGR02168; HMM-score: 6.7)
    Genetic information processingDNA metabolismChromosome-associated proteinschromosome segregation protein SMC (TIGR02168; HMM-score: 6.7)
    Genetic information processingMobile and extrachromosomal element functionsPlasmid functionsintegrating conjugative element protein, PFL_4705 family (TIGR03752; HMM-score: 5.7)
    type IV conjugative transfer system protein TraV (TIGR02747; HMM-score: 5.5)
    Genetic information processingTranscriptionDegradation of RNAribonuclease Y (TIGR03319; EC 3.1.-.-; HMM-score: 5.5)
    Cellular processesCellular processesCell divisionchromosome segregation protein SMC (TIGR02169; HMM-score: 5.3)
    Genetic information processingDNA metabolismChromosome-associated proteinschromosome segregation protein SMC (TIGR02169; HMM-score: 5.3)
    Cellular processesCellular processesCell divisioncell division protein FtsL (TIGR02209; HMM-score: 5.1)
    Genetic information processingProtein fateProtein and peptide secretion and traffickingmembrane protein insertase, YidC/Oxa1 family (TIGR03592; HMM-score: 5.1)
    MetabolismTransport and binding proteinsCations and iron carrying compoundsferrous iron transport protein B (TIGR00437; HMM-score: 4.2)
    Cellular processesCellular processesCell divisioncell division protein FtsN (TIGR02223; HMM-score: 4.1)
    Cellular processesCellular processesSporulation and germinationstage III sporulation protein AE (TIGR02829; HMM-score: 3.2)
  • TheSEED:  
    FIG01108219: hypothetical protein 
  • PFAM:
    no clan definedTolA_bind_tri; TolA binding protein trimerisation (PF16331; HMM-score: 19.5)
    BCLiA (CL0551) APG6; Autophagy protein Apg6 (PF04111; HMM-score: 16.9)
    no clan definedIncA; IncA protein (PF04156; HMM-score: 14.6)
    Leu_zip; Leucine zipper (PF15294; HMM-score: 13.4)
    Striatin; Striatin family (PF08232; HMM-score: 12)
    DUF3450; Protein of unknown function (DUF3450) (PF11932; HMM-score: 11.7)
    FtsL (CL0225) DivIC; Septum formation initiator (PF04977; HMM-score: 10)
    AhpD-like (CL0423) PA26; PA26 p53-induced protein (sestrin) (PF04636; HMM-score: 9.3)
    no clan definedFmp27_WPPW; RNA pol II promoter Fmp27 protein domain (PF10359; HMM-score: 9.2)
    NYD-SP28_assoc; Sperm tail C-terminal domain (PF14775; HMM-score: 9.1)
    BRI3BP; Negative regulator of p53/TP53 (PF14965; HMM-score: 9)
    V_ATPase_I; V-type ATPase 116kDa subunit family (PF01496; HMM-score: 8.5)
    SlyX; SlyX (PF04102; HMM-score: 8.1)
    DDHD; DDHD domain (PF02862; HMM-score: 7.9)
    YabB; Initiation control protein YabA (PF06156; HMM-score: 7.9)
    MctB; Copper transport outer membrane protein, MctB (PF11382; HMM-score: 6.9)
    SpoIIIAH; SpoIIIAH-like protein (PF12685; HMM-score: 6.8)
    ADIP; Afadin- and alpha -actinin-Binding (PF11559; HMM-score: 6.6)
    GPCR_A (CL0192) SID-1_RNA_chan; dsRNA-gated channel SID-1 (PF13965; HMM-score: 6.4)
    no clan definedMIP-T3; Microtubule-binding protein MIP-T3 (PF10243; HMM-score: 6.4)
    Peptidase_AD (CL0130) Presenilin; Presenilin (PF01080; HMM-score: 6.4)
    no clan definedSAPS; SIT4 phosphatase-associated protein (PF04499; HMM-score: 5.6)
    DUF1510; Protein of unknown function (DUF1510) (PF07423; HMM-score: 5.4)
    SLC12; Solute carrier family 12 (PF03522; HMM-score: 5.2)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0.24
    • Cytoplasmic Membrane Score: 0.05
    • Cellwall Score: 0.8
    • Extracellular Score: 8.91
    • Internal Helices: 0
  • LocateP: Lipid anchored
    • Prediction by SwissProt Classification: Extracellular
    • Pathway Prediction: Sec-(SPII)
    • Intracellular Possibility: 0
    • Signal Peptide Possibility: 0.5
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: LFLTGCG
  • SignalP: Signal peptide length 22 aa
    • Ymax: 0.408
    • Ymax_pos: 22
    • Cmax: 0.233
    • Cmax_pos: 26
    • Smax: 0.895
    • Smax_pos: 19
    • Smean: 0.771
    • D: 0.55
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MKKLIISIMAVMLFLTGCGKSQEKATLEKDIDNLQKENKELKDKKEKLQQEKEKLADKQKDLEKEVKDLKPSKEDNKDDKKDEDKNKDKDKDKEASQDKQSKDQTKSSDKDNHKKPTSADKDQKANDKHQS

Experimental data[edit source | edit]

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]