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Pangenome04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40
NCBI: 10-JUN-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL1578 [new locus tag: SACOL_RS08040 ]
  • pan locus tag?: SAUPAN004095000
  • symbol: SACOL1578
  • pan gene symbol?:
  • synonym:
  • product: FtsK/SpoIIIE family protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL1578 [new locus tag: SACOL_RS08040 ]
  • symbol: SACOL1578
  • product: FtsK/SpoIIIE family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1613132..1614490
  • length: 1359
  • essential: unknown

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGGCAATGAATGAAATTGCTTTATTTAAAGGCGTACGTATACAGCCTTATCAGAAGTAT
    ATTGATTTTATGTTTGCAAGTGTATTAGCATTTATTTTTTTGGTATATCGTATATACATT
    TTGTTTATTGATTATAAATCAGTTAATAAAAAATTGGATATATTGACGTTGTTTGCATAT
    TTTAAACCGCATTTATTGTATTTATTAATTGGTACAGCAATTATATTTGTTATATGTAAG
    CTTATCGCTCAGCTTTTAATTCGTTTTAAAACAAAAGATTTAGCTGAAATGATTGAAACA
    CAAGGCTTTCATAATCGTACAGTAATCAAGAAAACAACCGAGTATATCCCTATTGATTAT
    AAACAAACTGAATATGACTATTATCCAACGATGTTTTATAAACGTGGTAAAAAAACTTTT
    GTTATTCATATTAAAAAAGACGGTTCGAGGTTTCAAGATAATTATTTAGAGTTAGAAACG
    ATTATTGAACCAATGTTTAATTCTGAATTAGTAGAAAAAAAGCATATTGGTCGTTATTTG
    AGATATGAATTTATGCCACTTAAATATAAAAAGCGTATTGTTATGAATGGCGAACAAGAA
    TCAAATACAATTTTTTATGATACAAAAATTGCTATTACGCATCAAATTACTTGGGATTTT
    GTGAAAGCACCTCATGGATTGGTTACAGGTATAACCGGAGGTGGTAAAACATATTTTTTA
    TTTTATGTGATTCGTGAGTTATTCCGTAGACATTCAGAAGTACGTTTATTAGACCCAAAA
    GTTTCAGATTTAAGCTTTATGAAGCGCGTTATTGGTGATGATAAAGTTGCAGATACTAAA
    GGTCAAATATTAAAACAATTGAGAGAAGCTAATAATGAAATGGAAGAGCGTTTTAGATTA
    ATGAATGATAGTTCGGATTATAAAATCGGAAATGATTTCCGTAATTTTGATATGCGCCCC
    TATTTCATTATTTTTGATGAGGTAACGGCTTTTACTTCAACTTTAGATAAAAAAGAATTA
    CAAGAAATGAATGATTATTTAATTAATATTATTATGAAAGGTCGTCAAGCTGGTGTATTT
    ATGTTTTTAACAGCACAAAGACCAGATGCAGATGTGATTAAAGGTAATGTGCGTGACCAA
    TTAGGGTTACGTGTGTCTTTAGGTAATTTGTCAAATGATGGTTATCGTATGACCTTTGGT
    CAAACTGATAAAGAATTTCAAACGATTCATGATAGTGATATCGGCCGAGGTTATATAACT
    ATACTTGGACAATATAATGAACCAATTTTATTTGATGCACCTTTAATGGAACAATATGAT
    TTTGTGGAAGATGTGAAACAAATATTAAATAAGGAGTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1359

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL1578 [new locus tag: SACOL_RS08040 ]
  • symbol: SACOL1578
  • description: FtsK/SpoIIIE family protein
  • length: 452
  • theoretical pI: 8.99433
  • theoretical MW: 53351.6
  • GRAVY: -0.233628

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Genetic information processingProtein fateProtein and peptide secretion and traffickingtype VII secretion protein EccCa (TIGR03924; HMM-score: 31.2)
    Genetic information processingProtein fateProtein and peptide secretion and traffickingtype VII secretion protein EssC (TIGR03928; HMM-score: 27.5)
    Genetic information processingProtein fateProtein and peptide secretion and traffickingtype VII secretion protein EccCb (TIGR03925; HMM-score: 27.2)
    Genetic information processingMobile and extrachromosomal element functionsOtherconjugative coupling factor TraD, SXT/TOL subfamily (TIGR03743; HMM-score: 20.6)
    Cellular processesCellular processesPathogenesistype II secretion system protein E (TIGR02533; HMM-score: 11.9)
    Genetic information processingProtein fateProtein and peptide secretion and traffickingtype II secretion system protein E (TIGR02533; HMM-score: 11.9)
  • TheSEED:  
    FIG01108595: hypothetical protein 
  • PFAM:
    P-loop_NTPase (CL0023) FtsK_SpoIIIE; FtsK/SpoIIIE family (PF01580; HMM-score: 37.9)
    AAA_10; AAA-like domain (PF12846; HMM-score: 16.9)
    DUF87; Domain of unknown function DUF87 (PF01935; HMM-score: 15.9)
    ResIII; Type III restriction enzyme, res subunit (PF04851; HMM-score: 15.2)
    AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 15.1)
    AAA_14; AAA domain (PF13173; HMM-score: 14.5)
    DUF853; Bacterial protein of unknown function (DUF853) (PF05872; HMM-score: 14)
    T2SSE; Type II/IV secretion system protein (PF00437; HMM-score: 13.4)
    no clan definedDHHC; DHHC palmitoyltransferase (PF01529; HMM-score: 8.7)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helices: 2
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.073
    • Ymax_pos: 70
    • Cmax: 0.11
    • Cmax_pos: 20
    • Smax: 0.08
    • Smax_pos: 1
    • Smean: 0.04
    • D: 0.06
  • predicted transmembrane helices (TMHMM): 2

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MAMNEIALFKGVRIQPYQKYIDFMFASVLAFIFLVYRIYILFIDYKSVNKKLDILTLFAYFKPHLLYLLIGTAIIFVICKLIAQLLIRFKTKDLAEMIETQGFHNRTVIKKTTEYIPIDYKQTEYDYYPTMFYKRGKKTFVIHIKKDGSRFQDNYLELETIIEPMFNSELVEKKHIGRYLRYEFMPLKYKKRIVMNGEQESNTIFYDTKIAITHQITWDFVKAPHGLVTGITGGGKTYFLFYVIRELFRRHSEVRLLDPKVSDLSFMKRVIGDDKVADTKGQILKQLREANNEMEERFRLMNDSSDYKIGNDFRNFDMRPYFIIFDEVTAFTSTLDKKELQEMNDYLINIIMKGRQAGVFMFLTAQRPDADVIKGNVRDQLGLRVSLGNLSNDGYRMTFGQTDKEFQTIHDSDIGRGYITILGQYNEPILFDAPLMEQYDFVEDVKQILNKE

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]