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Pangenome04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40
NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS00360 [old locus tag: SACOL0070 ]
  • pan locus tag?: SAUPAN000385000
  • symbol: SACOL_RS00360
  • pan gene symbol?:
  • synonym:
  • product: MFS transporter

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS00360 [old locus tag: SACOL0070 ]
  • symbol: SACOL_RS00360
  • product: MFS transporter
  • replicon: chromosome
  • strand: -
  • coordinates: 78530..79750
  • length: 1221
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (78530..79750) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGACTGATTTGTTGAAAATTAAAAACTTCAGATTGTTCTTTTTAGCAGAAATAATTTCA
    GCATTCGGAGTTGGAATTAGTACAGTTGGGGCTAATTGGTATTTAATCGACAAAACTAAC
    GACTCCCAACTATTAGGTATTATGTTAGCTTTAAATGTATTATCCGGTTTCTTAGCTTCT
    CCTATAATAGGTGGACTAGCCGATAAATATAATAGACGAAATATTATTTTAATCACCTAT
    CTTCTTCAGGTAATATTATATTTACTCATTGTCATAGCACTCGTAATGATAGGATTTGAG
    ACCTATTTAGTGATTGGATTTGCGATTGTTAATGGGATAGGTTGGACTACGTATATGGCA
    ACATCTAGAAGTTTAGTTAAACAGATATTAAAACCAGATCAATATACAGATGCAAATTCT
    CTATTAGAGATTAGTTTGCAAACAGGTATGTTTATTGCAGGTGGATTATCAGGAATATTA
    TATAAAATAAATGGATTCACTCTAATTATAGCGATGACTATAATGATGTTTCTAATCAGC
    ATTTTTATGTTATTTAGATTGCATGTAGATAAACCAACTCATTCAGAGGAAGAATCAACA
    AATAGCTTATTGCAAGAATATTTATTAGGATGGAAATTTTTAAAAGACAACATGATGATA
    TTTATTTTTGGAGTTATTTCAATCATACCAATGGTGTTTACAATGATCTTTAACATATCA
    TTACCAGGATATGTTTATAATGTTTTAAAACTTTCGTCTGTACAATTTGGTTTTTCAGAT
    ATGTTATATGGCATTGGAGGATTATGTGCAGGTTTAATTTCAGCTATTCTTTCGAAGAAA
    ATCTCAACTAAAGTATTGATATTTTTGTTATATTTCATATTAGTCATAAATTCAGCACTA
    TTTATTTGGATAAACTCAGCATTTTACTTATTCATAGGATCATTTATACTAGGCTACTCA
    ATTTCATCAATCAGAATTTATATGAATACAGCTATAATGAACACTGTTTCAGATAAATAT
    GTCGGTCGCTCATTTACGATATGGACGTCAATTTCATTGTTACTGCAAAGTTTAATTGCT
    CCATTTTTAGGAAGATGGATTAATGAAATTAATGATAAATTCGGTTTCTATATTATACTC
    ATTTTATCCTTACTCATATTTGTTACACTGCTGCTTGTTAACAAAACAGACAAAATAAAA
    TATGCACATAAAGAAGAGTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1221

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS00360 [old locus tag: SACOL0070 ]
  • symbol: SACOL_RS00360
  • description: MFS transporter
  • length: 406
  • theoretical pI: 9.43757
  • theoretical MW: 45716.5
  • GRAVY: 0.86798

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismTransport and binding proteinsCations and iron carrying compoundsH+ Antiporter protein (TIGR00900; HMM-score: 165.1)
    multidrug resistance protein (TIGR00880; HMM-score: 67.8)
    MetabolismTransport and binding proteinsUnknown substrateMFS transporter, metabolite:H+ symporter (MHS) family protein (TIGR00883; HMM-score: 26.6)
    Cellular processesCellular processesToxin production and resistancedrug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family (TIGR00711; HMM-score: 19.4)
    MetabolismTransport and binding proteinsOtherdrug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family (TIGR00711; HMM-score: 19.4)
    MetabolismTransport and binding proteinsCations and iron carrying compoundscation transport protein (TIGR00898; HMM-score: 16.3)
    MetabolismTransport and binding proteinsCarbohydrates, organic alcohols, and acidsphosphoglycerate transporter family protein (TIGR00881; HMM-score: 12.6)
    MetabolismTransport and binding proteinsAnionsnitrite transporter (TIGR00886; HMM-score: 8.8)
    MetabolismTransport and binding proteinsCarbohydrates, organic alcohols, and acidssugar (Glycoside-Pentoside-Hexuronide) transporter (TIGR00792; HMM-score: 7.9)
  • TheSEED:
  • PFAM:
    MFS (CL0015) MFS_1; Major Facilitator Superfamily (PF07690; HMM-score: 109)
    MFS_3; Transmembrane secretion effector (PF05977; HMM-score: 60)
    MFS_2; MFS/sugar transport protein (PF13347; HMM-score: 30.5)
    Sugar_tr; Sugar (and other) transporter (PF00083; HMM-score: 18.7)
    MFS_1_like; MFS_1 like family (PF12832; HMM-score: 9.2)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 12
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.21
    • Ymax_pos: 32
    • Cmax: 0.187
    • Cmax_pos: 32
    • Smax: 0.355
    • Smax_pos: 13
    • Smean: 0.241
    • D: 0.222
  • predicted transmembrane helices (TMHMM): 12

Accession numbers[edit source | edit]

  • GI: 446052909 NCBI
  • RefSeq: WP_000130764 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MTDLLKIKNFRLFFLAEIISAFGVGISTVGANWYLIDKTNDSQLLGIMLALNVLSGFLASPIIGGLADKYNRRNIILITYLLQVILYLLIVIALVMIGFETYLVIGFAIVNGIGWTTYMATSRSLVKQILKPDQYTDANSLLEISLQTGMFIAGGLSGILYKINGFTLIIAMTIMMFLISIFMLFRLHVDKPTHSEEESTNSLLQEYLLGWKFLKDNMMIFIFGVISIIPMVFTMIFNISLPGYVYNVLKLSSVQFGFSDMLYGIGGLCAGLISAILSKKISTKVLIFLLYFILVINSALFIWINSAFYLFIGSFILGYSISSIRIYMNTAIMNTVSDKYVGRSFTIWTSISLLLQSLIAPFLGRWINEINDKFGFYIILILSLLIFVTLLLVNKTDKIKYAHKEE

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS00360 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]