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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS00440 [old locus tag: SACOL0088 ]
  • pan locus tag?: SAUPAN000899000
  • symbol: SACOL_RS00440
  • pan gene symbol?:
  • synonym:
  • product: Na/Pi cotransporter

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS00440 [old locus tag: SACOL0088 ]
  • symbol: SACOL_RS00440
  • product: Na/Pi cotransporter
  • replicon: chromosome
  • strand: -
  • coordinates: 98200..99861
  • length: 1662
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (98200..99861) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
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    421
    481
    541
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    661
    721
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    841
    901
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    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    ATGTCGGTTACAGAAGTCATTTTCTCCTTTTTAGGTGGTTTAGGTATTTTCCTTTACGGC
    TTAAAAATCATGGGAGACGGGCTTCAAGCATCAGCAGGAGACAGGCTACGAGATATTTTA
    AACAAATTTACATCAAATCCAGTATTAGGTGTTATTGCAGGTATCGTTGTAACTATTTTA
    ATACAAAGTAGTTCAGGTACGACAGTTATCACAATCGGACTGGTAACAGCTGGATTTATG
    ACATTGAAACAAGCCATTGGAGTGATAATGGGTGCTAATATCGGAACAACGGTAACTGCA
    TTTATTATCGGTATAGATTTAGGCGAATATGCAATGCCAATTTTAGCATTAGGTGCATTC
    TTAATCTTTTTCTTTAAACGCTCTAAAATCAATAACATTGGCCGCATACTATTCGGTTTC
    GGTTCACTATTCTTCGGTCTAGAATTTATGGGTGATGCCGTTAAACCTTTAGCATCATTA
    GATGGATTTAAGCAATTAATGCTTGATATGTCTACAAATCCAATACTCGCTGTCATTGTC
    GGCGCAGGGTTAACAGCACTAGTTCAAAGTTCAAGTGCGACGATTGGTATTTTACAAGAA
    TTTTATCAACAAGATTTAATTAGCTTAAACGCAGCAATCCCTGTGTTACTAGGCGATAAC
    ATTGGTACCACGATTACAGCTATCTTAGCTAGTTTAGCCGGCTCAATCGCTGCAAAACGT
    GCGGCGCTTGTACACGTCATCTTTAACTTAATCGGGGTAATTATCTTCACAATTTTCTTG
    CCAGTTGTGATTCATTTGATTAGTTTGTTACAAGATTTATGGCACTTAAAACCAGCGATG
    ACGATTGCAGTATCACATGGTATCTTCAACATAACAAATACTTTGATTCAATTACCATTT
    GTAGCAGGTTTAGCATGGATTGTTACAAAGCTTGTCCCAGGTAAAGATATTGCTGATGAC
    TATAAACCTCAGCACTTAAACAAAGATCTTGTTTATCACGCACCTGGTGTTGCATTACAA
    GAAACTCAAAAAGAATTACAAAATGTGGGTCAGATTGTCTTATCAATGTTTGAAGACATT
    CGCGAAATTACAAAAGACGATAAAAAATTGATCAAAAAGCTTGAACAAAAGCATCAAGCT
    GTTGAAACAATCAATGATAGCATTCGAAATTATTTAGTTAGAATTTCTACAAAAGCCATT
    ACGAAGGCAGACGTTGAGCGTTTAGCAGTTATGTTTGATGTCAATCGCTCTATTTTAAAA
    GTAGCAGAGCTAACAGAAGAGTATGTCGCTCAATTAAAACGCCAACATGATGAAGATATT
    CGCATTACAGAAGATGCACAACGCGGTATGGATAAATTATTCAACCATGTTGCTGAGTCA
    TTTGATAAAGCCATCGACATGTTAGATGTTTATGACAAAACGAAAAAAGATGAAATTGTA
    GAACGTAGTAGAGAATCATTTAATATTGAACATAAACTACGCAAAGGTCATATTAAACGC
    CTTAATCGTGGTGAATGTACAACAAAAGGCGGATTACTATATATCGATATGATTGGTGTT
    CTTGAACGTATCGGTTATCATTCACGAAATGTTTCTGAAGCACTTGTTGGCCTTAACGAT
    GATGTACCTACAGATGAAGAAATTGCAACAACTGAAATTTAA
    60
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    1020
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    1140
    1200
    1260
    1320
    1380
    1440
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    1560
    1620
    1662

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS00440 [old locus tag: SACOL0088 ]
  • symbol: SACOL_RS00440
  • description: Na/Pi cotransporter
  • length: 553
  • theoretical pI: 6.38787
  • theoretical MW: 60647.5
  • GRAVY: 0.333454

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismTransport and binding proteinsCations and iron carrying compoundsNa/Pi-cotransporter II-related protein (TIGR00704; HMM-score: 250.1)
    MetabolismTransport and binding proteinsCations and iron carrying compoundssodium-dependent inorganic phosphate (Pi) transporter (TIGR01013; HMM-score: 121.5)
    MetabolismTransport and binding proteinsAnionsphosphate transport system regulatory protein PhoU (TIGR02135; HMM-score: 34.8)
    Signal transductionRegulatory functionsOtherphosphate transport system regulatory protein PhoU (TIGR02135; HMM-score: 34.8)
  • TheSEED:
  • PFAM:
    no clan definedNa_Pi_cotrans; Na+/Pi-cotransporter (PF02690; HMM-score: 234.3)
    PhoU (CL0297) PhoU; PhoU domain (PF01895; HMM-score: 49.8)
    no clan definedApoO; Apolipoprotein O (PF09769; HMM-score: 13.8)
    Mis12; Mis12 protein (PF05859; HMM-score: 13.4)
    HUP (CL0039) tRNA-synt_1e; tRNA synthetases class I (C) catalytic domain (PF01406; HMM-score: 11.8)
    no clan definedIBP39; Initiator binding protein 39 kDa (PF11422; HMM-score: 11.7)
    MutS_III; MutS domain III (PF05192; HMM-score: 11.1)
    KxDL; Uncharacterized conserved protein (PF10241; HMM-score: 8.2)
    Med30; Mediator complex subunit 30 (PF11315; HMM-score: 7.9)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 9
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.145
    • Ymax_pos: 33
    • Cmax: 0.137
    • Cmax_pos: 33
    • Smax: 0.197
    • Smax_pos: 25
    • Smean: 0.112
    • D: 0.132
  • predicted transmembrane helices (TMHMM): 9

Accession numbers[edit source | edit]

  • GI:
  • RefSeq: WP_001791835 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MSVTEVIFSFLGGLGIFLYGLKIMGDGLQASAGDRLRDILNKFTSNPVLGVIAGIVVTILIQSSSGTTVITIGLVTAGFMTLKQAIGVIMGANIGTTVTAFIIGIDLGEYAMPILALGAFLIFFFKRSKINNIGRILFGFGSLFFGLEFMGDAVKPLASLDGFKQLMLDMSTNPILAVIVGAGLTALVQSSSATIGILQEFYQQDLISLNAAIPVLLGDNIGTTITAILASLAGSIAAKRAALVHVIFNLIGVIIFTIFLPVVIHLISLLQDLWHLKPAMTIAVSHGIFNITNTLIQLPFVAGLAWIVTKLVPGKDIADDYKPQHLNKDLVYHAPGVALQETQKELQNVGQIVLSMFEDIREITKDDKKLIKKLEQKHQAVETINDSIRNYLVRISTKAITKADVERLAVMFDVNRSILKVAELTEEYVAQLKRQHDEDIRITEDAQRGMDKLFNHVAESFDKAIDMLDVYDKTKKDEIVERSRESFNIEHKLRKGHIKRLNRGECTTKGGLLYIDMIGVLERIGYHSRNVSEALVGLNDDVPTDEEIATTEI

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS00440 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]