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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS05015 [old locus tag: SACOL0980 ]
  • pan locus tag?: SAUPAN003114000
  • symbol: SACOL_RS05015
  • pan gene symbol?:
  • synonym:
  • product: LysR family transcriptional regulator

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS05015 [old locus tag: SACOL0980 ]
  • symbol: SACOL_RS05015
  • product: LysR family transcriptional regulator
  • replicon: chromosome
  • strand: -
  • coordinates: 988915..989784
  • length: 870
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (988915..989784) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
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    ATGAATTTAGATTGGTACTATACATTTGTCATTTTAGCGAAGACGTTAAACTATCGATTA
    GCTAGTGAAGAAATTAATCTCACTATACCTTCTATACATAAGCAAATTAAAAATTTAGAA
    CAGCATCTCAATGTGAAACTATTTGAAACTTATAAAAATCAAATTATCTTGACTGAAGAT
    GGTCATACATTTCTTCCAATTGCGCAAAGTTTTATTGAACAATATGAAAGTGGCATCAAA
    CATATCCAACTTAAAAAAACGATGTTTCAATCGAAATTAAATGTTGTCGTGTCTTCATAT
    ATCGCGACATTCATTATGCCCAAATTTTTAAAATCTTTCTTTAACGAGCATCCTTTTATC
    GATGTTTCTCTTCATGTCAAAAATGAAAATATTGAAAAAGATATTAATAATCATACGTAT
    GACATCGGGATTAGCAGAAATCAACCTAAACTAAGAGAAGTTCATTCTGAAAAAGTATGC
    GAAGGTAAAATTGTATTGATTGCTCCCAATAAAGAGAATAATCATCTTCTAACTGAGGCA
    TCTTTATTTGAAAAATACAAAATAATAAGTGATAACCATCCAGAATATTGGTCATCACTT
    AAAAATAATATTTTAAATATTTATGAAAAAGCACAATTTCTATCTATCAATGATGTGCAT
    ACTTCAATTAAATTAATCGAAATGAATCAAGGTATATCATTCCTGCCTCTTTATATAACA
    ACAAATAGTGATTACAATATTTCGGTTATTAACACGAAAATTTTACAAGCACCTATTTCA
    TTTACATATATATACAGCAAAAAAGAAAGCCCAGAAATATTGGTGTTTATTAAATCATTT
    AAAAAGTATATTGCCAATGAACAATTATAA
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Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS05015 [old locus tag: SACOL0980 ]
  • symbol: SACOL_RS05015
  • description: LysR family transcriptional regulator
  • length: 289
  • theoretical pI: 8.35837
  • theoretical MW: 33798.7
  • GRAVY: -0.229412

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Signal transductionRegulatory functionsDNA interactionsaminoethylphosphonate catabolism associated LysR family transcriptional regulator (TIGR03339; HMM-score: 64.5)
    putative choline sulfate-utilization transcription factor (TIGR03418; HMM-score: 52.1)
    MetabolismEnergy metabolismOtherpca operon transcription factor PcaQ (TIGR02424; HMM-score: 49.5)
    Signal transductionRegulatory functionsDNA interactionspca operon transcription factor PcaQ (TIGR02424; HMM-score: 49.5)
    Signal transductionRegulatory functionsDNA interactionsD-serine deaminase transcriptional activator (TIGR02036; HMM-score: 47.5)
    Cellular processesCellular processesToxin production and resistancetranscriptional regulator, ArgP family (TIGR03298; HMM-score: 11.2)
    Genetic information processingDNA metabolismDNA replication, recombination, and repairtranscriptional regulator, ArgP family (TIGR03298; HMM-score: 11.2)
    Signal transductionRegulatory functionsDNA interactionstranscriptional regulator, ArgP family (TIGR03298; HMM-score: 11.2)
  • TheSEED:
  • PFAM:
    PBP (CL0177) LysR_substrate; LysR substrate binding domain (PF03466; HMM-score: 79.5)
    HTH (CL0123) HTH_1; Bacterial regulatory helix-turn-helix protein, lysR family (PF00126; HMM-score: 43.7)
    SUKH (CL0526) SUKH_6; SMI1-KNR4 cell-wall (PF14568; HMM-score: 11.7)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.67
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 0.15
    • Extracellular Score: 0.17
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.127
    • Ymax_pos: 22
    • Cmax: 0.174
    • Cmax_pos: 22
    • Smax: 0.17
    • Smax_pos: 21
    • Smean: 0.093
    • D: 0.114
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446969810 NCBI
  • RefSeq: WP_001047066 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MNLDWYYTFVILAKTLNYRLASEEINLTIPSIHKQIKNLEQHLNVKLFETYKNQIILTEDGHTFLPIAQSFIEQYESGIKHIQLKKTMFQSKLNVVVSSYIATFIMPKFLKSFFNEHPFIDVSLHVKNENIEKDINNHTYDIGISRNQPKLREVHSEKVCEGKIVLIAPNKENNHLLTEASLFEKYKIISDNHPEYWSSLKNNILNIYEKAQFLSINDVHTSIKLIEMNQGISFLPLYITTNSDYNISVINTKILQAPISFTYIYSKKESPEILVFIKSFKKYIANEQL

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS05015 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]