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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS06870 [old locus tag: SACOL1349 ]
  • pan locus tag?: SAUPAN003680000
  • symbol: SACOL_RS06870
  • pan gene symbol?:
  • synonym:
  • product: low specificity L-threonine aldolase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS06870 [old locus tag: SACOL1349 ]
  • symbol: SACOL_RS06870
  • product: low specificity L-threonine aldolase
  • replicon: chromosome
  • strand: -
  • coordinates: 1356182..1357207
  • length: 1026
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (1356182..1357207) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    GTGATTTCATTCGAAAATGATTATTTAGAAGGTGCTCATGAAAAAGTATTAAAACGATTA
    GTAGATACAAATCTTGTACAAGCTTCGGGATATGGCTTTGATCAATTCACAGCTCAGGCA
    ATTGAAAAGATTAAAGATACAATTGACTGTCCAAATGCTACAATTCGTTTTTTAGTAGGT
    GGAACACAAACCAATCAGGTTGTTATTAATTCAATGTTAGAAAGTTACGAAGGGGTCATT
    TCAGCAGACACTGGTCATGTTGCTGTGCATGAGGGCGGTGCAATTGAATATAGTGGACAT
    AAAGTAATTACTATACCCTCTAAGGAAGGAAAAGTTAGTGCTTCAGATGTTGAAACTTAC
    ATGGAGACATTTAAAAGTGATTTTAAAAAGGACCATATGGTATTCCCAGGAATGGTATAT
    ATTTCTCATCCTACAGAATATGGCACATTATACTCTAAATCAGAATTGGAAGAGTTATGC
    AAAGTATGTAAGCAATATCAGCTTCCATTATTTATGGATGGTGCACGATTAGGGTATGGA
    TTGATGAGTGACCAATCAGATATGACTATTAAAGACATCGCTAAATATTGTGATGTATTT
    TATATAGGTGGTACGAAGATAGGTGCATTATGCGGGGAAGCCATTGTTTTTACGAAAAAT
    AATGAACCGAAACAATTTACCACTCGAATCAAGCATCACGGTGCCCTTTTAGCAAAAGGA
    CGGTTAACAGGCATACAATTTTTAGAATTATTTACGGACAATTTATATTTTAATATAAGC
    AGACATGCTATCGAAATGGCAAATAAGATGAAAGACGGGTTTAAAAATAAAGGCTATCGT
    CTTTACTTTGATTCTCCAACCAATCAACAATTTTTTATTTTAAGTAACGAGAAAATAGCA
    GAGTTAGAACAAAAAGTTAAATTTGCTGTTTGGGAAAAATACGATGATCAACATCGTGTT
    GTTAGATTCGCAACCAGTTGGGCGACAACCGAAGAAAATTTAAATAAACTATTAGAATTA
    ATCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1026

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS06870 [old locus tag: SACOL1349 ]
  • symbol: SACOL_RS06870
  • description: low specificity L-threonine aldolase
  • length: 341
  • theoretical pI: 6.18837
  • theoretical MW: 38633.8
  • GRAVY: -0.293548

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    O-phospho-L-seryl-tRNA:Cys-tRNA synthase (TIGR02539; EC 2.5.1.73; HMM-score: 22.3)
    MetabolismBiosynthesis of cofactors, prosthetic groups, and carriersOthertyrosine decarboxylase MnfA (TIGR03812; EC 4.1.1.25; HMM-score: 20.3)
    cysteine desulfurase NifS (TIGR03402; EC 2.8.1.7; HMM-score: 16.7)
    aminotransferase, LLPSF_NHT_00031 family (TIGR04181; HMM-score: 12.3)
    MetabolismBiosynthesis of cofactors, prosthetic groups, and carriersOthercoenzyme PQQ biosynthesis protein PqqD (TIGR03859; HMM-score: 12.1)
  • TheSEED:
  • PFAM:
    PLP_aminotran (CL0061) Beta_elim_lyase; Beta-eliminating lyase (PF01212; HMM-score: 100.1)
    Aminotran_1_2; Aminotransferase class I and II (PF00155; HMM-score: 25.3)
    Aminotran_5; Aminotransferase class-V (PF00266; HMM-score: 22.7)
    SepSecS; O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS (PF05889; HMM-score: 14.1)
    Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain (PF00282; HMM-score: 11.3)
    GHD (CL0369) DUF1945; Domain of unknown function (DUF1945) (PF09178; HMM-score: 8.7)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.184
    • Ymax_pos: 41
    • Cmax: 0.264
    • Cmax_pos: 41
    • Smax: 0.158
    • Smax_pos: 37
    • Smean: 0.104
    • D: 0.153
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446545354 NCBI
  • RefSeq: WP_000622700 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MISFENDYLEGAHEKVLKRLVDTNLVQASGYGFDQFTAQAIEKIKDTIDCPNATIRFLVGGTQTNQVVINSMLESYEGVISADTGHVAVHEGGAIEYSGHKVITIPSKEGKVSASDVETYMETFKSDFKKDHMVFPGMVYISHPTEYGTLYSKSELEELCKVCKQYQLPLFMDGARLGYGLMSDQSDMTIKDIAKYCDVFYIGGTKIGALCGEAIVFTKNNEPKQFTTRIKHHGALLAKGRLTGIQFLELFTDNLYFNISRHAIEMANKMKDGFKNKGYRLYFDSPTNQQFFILSNEKIAELEQKVKFAVWEKYDDQHRVVRFATSWATTEENLNKLLELI

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS06870 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]