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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS11030 [old locus tag: SACOL2108 ]
  • pan locus tag?: SAUPAN005407000
  • symbol: SACOL_RS11030
  • pan gene symbol?:
  • synonym:
  • product: threonylcarbamoyl-AMP synthase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS11030 [old locus tag: SACOL2108 ]
  • symbol: SACOL_RS11030
  • product: threonylcarbamoyl-AMP synthase
  • replicon: chromosome
  • strand: -
  • coordinates: 2167902..2168999
  • length: 1098
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (2167902..2168999) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    GTGCATAGCTTTTTGCTTTATATTATGATAAATAAGAAAGGCGTGATTAAGTTGGATACT
    AAAATTTGGGATGTTAGAGAATATAATGAAGATTTACAGCAATATCCTAAAATTAATGAA
    ATAAAAGACATTGTTTTAAACGGTGGTTTAATAGGTTTACCAACTGAAACAGTTTATGGA
    CTTGCAGCAAATGCGACAGATGAAGAAGCTGTAGCTAAAATATATGAAGCTAAAGGCCGT
    CCATCTGACAATCCGCTTATTGTTCATATACACAGTAAAGGTCAATTAAAAGATTTTACA
    TATACTTTGGATCCACGCGTAGAAAAGTTAATGCAGGCATTCTGGCCGGGCCCTATTTCG
    TTTATATTGCCGTTAAAGCTAGGCTATCTATGTCGAAAAGTTTCTGGAGGTTTATCATCA
    GTTGCTGTTAGAATGCCAAGCCATTCTGTAGGTAGACAATTATTACAAATCATAAATGAA
    CCTCTAGCTGCTCCAAGTGCTAATTTAAGTGGTAGACCTTCACCAACAACTTTCAATCAT
    GTATATCAAGATTTGAATGGCCGTATCGATGGTATTGTTCAAGCTGAACAAAGTGAAGAA
    GGATTAGAAAGTACGGTTTTAGATTGCACATCTTTTCCTTATAAAATTGCAAGACCTGGT
    TCTATAACAGCAGCAATGATTACAGAAATACTTCCGAATAGTATCGCCCATGCTGATTAT
    AATGATACTGAACAGCCAATTGCACCAGGTATGAAGTATAAGCATTACTCACCCAATACA
    CCACTTACAATTATTACAGATATTGAGAGCAAAATTGGAAATGACGGTAAAGATTGGTCT
    TCTATAGCTTTTATTGTGCCGAGTAATAAGGTGGCGTTTATACCAAGTGAAGCGCAATTC
    ATTCAATTATGTCAGGATGACAATGATGTTAAACAAGCAAGTCATAATCTTTATGATGTG
    TTACATTCACTTGATGAAAATGAAAATATTTCAGCGGCGTATATATACGGCTTTGAGCTG
    AATGATAATACAGAAGCAATTATGAATCGCATGTTAAAAGCTGCAGGTAATCACATTATT
    AAAGGATGTGAACTATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1098

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS11030 [old locus tag: SACOL2108 ]
  • symbol: SACOL_RS11030
  • description: threonylcarbamoyl-AMP synthase
  • length: 365
  • theoretical pI: 5.23175
  • theoretical MW: 40444.8
  • GRAVY: -0.22137

Function[edit source | edit]

  • reaction:
    EC 2.7.7.87?  ExPASy
    L-threonylcarbamoyladenylate synthaseL-threonine + ATP + HCO3(-) = L-threonylcarbamoyladenylate + diphosphate + H2O
  • TIGRFAM:
    Genetic information processingProtein synthesistRNA and rRNA base modificationtRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family (TIGR00057; HMM-score: 194.3)
    Genetic information processingProtein fateProtein modification and repaircarbamoyltransferase HypF (TIGR00143; HMM-score: 27.2)
  • TheSEED:
  • PFAM:
    no clan definedSua5_yciO_yrdC; Telomere recombination (PF01300; HMM-score: 179.2)
    GT-B (CL0113) SUA5; Putative GTP-binding controlling metal-binding (PF03481; HMM-score: 76.3)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.142
    • Ymax_pos: 18
    • Cmax: 0.112
    • Cmax_pos: 63
    • Smax: 0.246
    • Smax_pos: 1
    • Smean: 0.188
    • D: 0.16
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI:
  • RefSeq: WP_011447046 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MHSFLLYIMINKKGVIKLDTKIWDVREYNEDLQQYPKINEIKDIVLNGGLIGLPTETVYGLAANATDEEAVAKIYEAKGRPSDNPLIVHIHSKGQLKDFTYTLDPRVEKLMQAFWPGPISFILPLKLGYLCRKVSGGLSSVAVRMPSHSVGRQLLQIINEPLAAPSANLSGRPSPTTFNHVYQDLNGRIDGIVQAEQSEEGLESTVLDCTSFPYKIARPGSITAAMITEILPNSIAHADYNDTEQPIAPGMKYKHYSPNTPLTIITDIESKIGNDGKDWSSIAFIVPSNKVAFIPSEAQFIQLCQDDNDVKQASHNLYDVLHSLDENENISAAYIYGFELNDNTEAIMNRMLKAAGNHIIKGCEL

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS11030 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]