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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS11485 [old locus tag: SACOL2183 ]
  • pan locus tag?: SAUPAN005588000
  • symbol: SACOL_RS11485
  • pan gene symbol?: lacD
  • synonym:
  • product: tagatose 1,6-diphosphate aldolase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS11485 [old locus tag: SACOL2183 ]
  • symbol: SACOL_RS11485
  • product: tagatose 1,6-diphosphate aldolase
  • replicon: chromosome
  • strand: -
  • coordinates: 2265985..2266965
  • length: 981
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (2265985..2266965) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
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    481
    541
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    721
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    841
    901
    961
    ATGTCAAAATCGAATCAAAAAATCGCATCAATTGAACAATTAAGTAACAACGAAGGTATC
    ATTTCTGCATTAGCATTTGACCAACGTGGTGCTTTAAAACGCATGATGGCAAAACATCAA
    ACTGAAGAACCAACTGTAGCTCAAATTGAACAATTAAAAGTATTAGTTGCGGAAGAATTA
    ACACAATATGCATCTTCAATTTTATTAGATCCTGAATATGGTTTACCAGCTTCAGATGCA
    CGTAACAAAGATTGTGGATTATTACTTGCTTATGAAAAAACTGGATATGACGTAAACGCT
    AAAGGTCGTTTACCTGACTGTTTAGTAGAGTGGTCTGCAAAACGTTTAAAAGAACAAGGC
    GCAAATGCTGTTAAATTCTTACTTTACTATGATGTTGATGATGCTGAAGAAATTAACATT
    CAAAAGAAAGCATACATTGAAAGAATCGGTTCAGAATGTGTTGCAGAAGATATTCCATTC
    TTTTTAGAAGTATTAACATACGATGACAACATTCCTGATAACGGTAGTGTTGAATTCGCA
    AAAGTTAAGCCTAGAAAGGTTAACGAAGCAATGAAATTATTCTCAGAACCACGCTTTAAC
    GTTGATGTATTGAAAGTTGAAGTACCAGTAAACATGAAATATGTAGAAGGCTTTGCTGAA
    GGTGAAGTGGTTTATACAAAAGAGGAAGCGGCACAACACTTTAAAGATCAAGATGCAGCA
    ACTCATTTACCATACATTTACTTAAGTGCTGGTGTTTCTGCGGAATTATTCCAAGAAACT
    TTAAAATTTGCTCACGAAGCTGGTGCTAAATTCAACGGGGTACTTTGTGGCCGTGCTACA
    TGGTCTGGTGCTGTTCAAGTATACATTGAACAAGGTGAAGATGCTGCTCGTGAATGGTTA
    CGTACAACTGGTTTCAAAAATATTGATGACTTAAATAAAGTATTAAAAGATACTGCGACA
    TCTTGGAAACAAAGAAAATAA
    60
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    981

Protein[edit source | edit]

Protein Data Bank: 3MYP

General[edit source | edit]

  • locus tag: SACOL_RS11485 [old locus tag: SACOL2183 ]
  • symbol: SACOL_RS11485
  • description: tagatose 1,6-diphosphate aldolase
  • length: 326
  • theoretical pI: 4.77016
  • theoretical MW: 36595.2
  • GRAVY: -0.389571

Function[edit source | edit]

  • reaction:
    EC 4.1.2.40?  ExPASy
    Tagatose-bisphosphate aldolaseD-tagatose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate
  • TIGRFAM:
    MetabolismEnergy metabolismBiosynthesis and degradation of polysaccharidestagatose 1,6-diphosphate aldolase (TIGR01232; EC 4.1.2.40; HMM-score: 717.7)
  • TheSEED:
  • PFAM:
    TIM_barrel (CL0036) DeoC; DeoC/LacD family aldolase (PF01791; HMM-score: 263.6)
    DUF2090; Uncharacterized protein conserved in bacteria (DUF2090) (PF09863; HMM-score: 26.8)
    no clan definedTIP41; TIP41-like family (PF04176; HMM-score: 12.9)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.118
    • Ymax_pos: 38
    • Cmax: 0.128
    • Cmax_pos: 38
    • Smax: 0.168
    • Smax_pos: 37
    • Smean: 0.104
    • D: 0.113
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 445969154 NCBI
  • RefSeq: WP_000047009 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MSKSNQKIASIEQLSNNEGIISALAFDQRGALKRMMAKHQTEEPTVAQIEQLKVLVAEELTQYASSILLDPEYGLPASDARNKDCGLLLAYEKTGYDVNAKGRLPDCLVEWSAKRLKEQGANAVKFLLYYDVDDAEEINIQKKAYIERIGSECVAEDIPFFLEVLTYDDNIPDNGSVEFAKVKPRKVNEAMKLFSEPRFNVDVLKVEVPVNMKYVEGFAEGEVVYTKEEAAQHFKDQDAATHLPYIYLSAGVSAELFQETLKFAHEAGAKFNGVLCGRATWSGAVQVYIEQGEDAAREWLRTTGFKNIDDLNKVLKDTATSWKQRK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS11485 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]