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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS13690 [old locus tag: SACOL2617 ]
  • pan locus tag?: SAUPAN006295000
  • symbol: SACOL_RS13690
  • pan gene symbol?: budA2
  • synonym:
  • product: alpha-acetolactate decarboxylase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS13690 [old locus tag: SACOL2617 ]
  • symbol: SACOL_RS13690
  • product: alpha-acetolactate decarboxylase
  • replicon: chromosome
  • strand: -
  • coordinates: 2673432..2674136
  • length: 705
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (2673432..2674136) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
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    481
    541
    601
    661
    ATGACGAATGTCTTGTATCAACATGGTACATTAGGTACGTTAATGGCTGGCTTACTAGAA
    GGCACAGCTACAATTAATGAATTGTTAGAACATGGGAATTTAGGGATTGCAACGTTAACA
    GGGTCTGATGGCGAAGTAATATTTTTAGACGGAAAGGCATATCATGCTAACGAGCATAAA
    GAATTTATAGAATTAAAAGGCGATGAGAAAGTACCGTATGCATCGATTACTAATTTTAAA
    GCGAGTAAGACATTTCCATTGCAACAATTATCACAAGATGATGTATTTGCACAAATTAAA
    AATGAAATGTTAAGTGAGAATTTATTTTCGGCTGTTAAAATTTATGGCACATTTAAACAT
    ATGCATGTACGAATGATGCCTGCTCAGCAACCGCCATATACACGTTTGATTGATTCAGCA
    CGCAGACAACCTGAGGAAAAAAGACAAGATATTCGTGGTGCCATTGTTGGATTTTTTACA
    CCAGAATTATTTCATGGCGTAGGGTCTGCTGGTTTTCATATACATTTTGCGGATGATGAA
    AGAGCTTATGGTGGACATGTTCTTGACTTTGAAGTGGATGACGTTGTCGTTGAGATACAA
    AACTTTGAAACATTCCAACAACATTTCCCGGTAAATAACGAGACGTTTGTTAAAGCGAAA
    ATAGACTATAACGATGTGGCAGAAGAAATTAGAGAAGCTGAATAG
    60
    120
    180
    240
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    360
    420
    480
    540
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    660
    705

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS13690 [old locus tag: SACOL2617 ]
  • symbol: SACOL_RS13690
  • description: alpha-acetolactate decarboxylase
  • length: 234
  • theoretical pI: 4.80636
  • theoretical MW: 26392.4
  • GRAVY: -0.341026

Function[edit source | edit]

  • reaction:
    EC 4.1.1.5?  ExPASy
    Acetolactate decarboxylase(2S)-2-hydroxy-2-methyl-3-oxobutanoate = (3R)-3-hydroxybutan-2-one + CO2
  • TIGRFAM:
    MetabolismEnergy metabolismFermentationalpha-acetolactate decarboxylase (TIGR01252; EC 4.1.1.5; HMM-score: 245.6)
  • TheSEED:
  • PFAM:
    ALDC (CL0615) AAL_decarboxy; Alpha-acetolactate decarboxylase (PF03306; HMM-score: 249.6)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.141
    • Ymax_pos: 29
    • Cmax: 0.134
    • Cmax_pos: 57
    • Smax: 0.246
    • Smax_pos: 20
    • Smean: 0.18
    • D: 0.156
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446108264 NCBI
  • RefSeq: WP_000186119 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MTNVLYQHGTLGTLMAGLLEGTATINELLEHGNLGIATLTGSDGEVIFLDGKAYHANEHKEFIELKGDEKVPYASITNFKASKTFPLQQLSQDDVFAQIKNEMLSENLFSAVKIYGTFKHMHVRMMPAQQPPYTRLIDSARRQPEEKRQDIRGAIVGFFTPELFHGVGSAGFHIHFADDERAYGGHVLDFEVDDVVVEIQNFETFQQHFPVNNETFVKAKIDYNDVAEEIREAE

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS13690 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]