From AureoWiki
Jump to: navigation, search
NCBI: 03-AUG-2016

Summary[edit source | edit]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_00932
  • pan locus tag?: SAUPAN003156000
  • symbol: SAOUHSC_00932
  • pan gene symbol?: opp-4C
  • synonym:
  • product: oligopeptide ABC transporter permease

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SAOUHSC_00932
  • symbol: SAOUHSC_00932
  • product: oligopeptide ABC transporter permease
  • replicon: chromosome
  • strand: +
  • coordinates: 904625..905506
  • length: 882
  • essential: no DEG other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGCAAAATAAGTCAAAATCGCCTTTTAAAATTGCATTTTCTAAATTTATTCATAATAAA
    ATTGCAATGTTATCGGTTATTTTTTTATTAATCATAACTATTGTATCAATTATAGCGCCA
    TTAATAGCTCCTTTTCCAGTGAACCAACAAGATTTATTAAATATAAAAGGTGAAATGACA
    GCACAAAACATTCTTGGTACAGACTCTGGTGGTAGGGATAACTTTAGTCGTTTGTTATAT
    GCAGGTCGTATTTCATTATCCATTGGAATTACATCTACAATAGGAATGCTTTTGATTGGA
    ATTACAGTTGGAGTGATTTCTGGTTATTTTGGAGGTATTGTTGATACATTATTAATGAGA
    ATAACCGAATTTGTTATGTTATTTCCATTTTTAATATTTGCAATTGTATTAAATGCTGCA
    CTTGGAGATAAAATTAAAAATCCTTATGGATCTGCCATAATTCTTGTTCTAGTTATTATC
    GTATTAAGTTGGGGAGGTATTGCAAGACTTGTTCGTGGTAAAGTACTTCAAGAAAAAGAA
    AATGAATACTTTTTGGCAGCAAAATCAATTGGTACACCCACATATAAAATTATTTTGAAA
    CATCTTTTGCCGAATATATTAAGTGTAGTTATCGTACAAGCAACATTGTTATTTGCCGGT
    ATGATTGTAGTGGAATCAGGATTGAGCTTTTTAGGATTCGGAATTAGTAAAGCAATACCA
    TCTTGGGGTAATATGTTGAGTGATGCTCAAGAAGGGGATGTTATAAGTGGTAAACCGTGG
    ATATGGATGCCACCTGCTATAATGATTACATTAACTATATTAAGTATAAACTTTGTAGGG
    GAAGGGATTAAAGATGCTTTTAATCCTAGAGGTAGACGTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    882

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SAOUHSC_00932
  • symbol: SAOUHSC_00932
  • description: oligopeptide ABC transporter permease
  • length: 293
  • theoretical pI: 10.4056
  • theoretical MW: 31819.9
  • GRAVY: 0.722526

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismTransport and binding proteinsCations and iron carrying compoundsnickel ABC transporter, permease subunit NikC (TIGR02790; EC 3.6.3.24; HMM-score: 202.1)
    MetabolismTransport and binding proteinsCations and iron carrying compoundsnickel ABC transporter, permease subunit NikB (TIGR02789; EC 3.6.3.24; HMM-score: 22.3)
    MetabolismTransport and binding proteinsAnionssulfate ABC transporter, permease protein CysT (TIGR02139; HMM-score: 19)
    MetabolismTransport and binding proteinsAmino acids, peptides and aminesputative 2-aminoethylphosphonate ABC transporter, permease protein (TIGR03262; HMM-score: 14.5)
  • TheSEED:  
    Membrane TransportABC transportersABC transporter oligopeptide (TC 3.A.1.5.1) Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1) 
  • PFAM:
    BPD_transp_1 (CL0404) BPD_transp_1; Binding-protein-dependent transport system inner membrane component (PF00528; HMM-score: 107.7)
    no clan definedOppC_N; N-terminal TM domain of oligopeptide transport permease C (PF12911; HMM-score: 41.8)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: 0
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.214
    • Ymax_pos: 11
    • Cmax: 0.117
    • Cmax_pos: 44
    • Smax: 0.575
    • Smax_pos: 1
    • Smean: 0.44
    • D: 0.302
  • predicted transmembrane helices (TMHMM): 6

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MQNKSKSPFKIAFSKFIHNKIAMLSVIFLLIITIVSIIAPLIAPFPVNQQDLLNIKGEMTAQNILGTDSGGRDNFSRLLYAGRISLSIGITSTIGMLLIGITVGVISGYFGGIVDTLLMRITEFVMLFPFLIFAIVLNAALGDKIKNPYGSAIILVLVIIVLSWGGIARLVRGKVLQEKENEYFLAAKSIGTPTYKIILKHLLPNILSVVIVQATLLFAGMIVVESGLSFLGFGISKAIPSWGNMLSDAQEGDVISGKPWIWMPPAIMITLTILSINFVGEGIKDAFNPRGRR

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator: SAOUHSC_01228 (CodY*)
    CodY* (TF) important in Amino acid metabolism  RegPrecise    transcription unit transferred from N315 data RegPrecise

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

  1. Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet.: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

Relevant publications[edit source | edit]