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NCBI: 03-AUG-2016

Summary[edit source | edit]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_01076
  • pan locus tag?: SAUPAN003353000
  • symbol: SAOUHSC_01076
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SAOUHSC_01076
  • symbol: SAOUHSC_01076
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1039996..1041135
  • length: 1140
  • essential: no DEG other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGAAAAGCGTTGGCTTAATCACAGAATATAATCCCTTTCATAATGGGCATCAATATCAT
    ATTAATCAATCTAAAAAACTTACAAATGCTGACGTTACTATTGCAATAATGAGTGGTAAC
    TTTGTCATGCGTGGCGAACCAGCAATCTATAATAAGTTTACTCGTGCAAAAATGGCATTA
    TCAACAGCTGATTTAGTTATCGAACTACCAGCAACTGCCAGTTTATCATCTGGCGATCAT
    TTTGCCGAACTAGCAGTTAAAGTCGCAGATTATATGAGTGTCGATACAATTGCATTTGGT
    AGTGAAAATAATGATATCAAAACATTAAAGCAATTAGCACACAGCATTAATGAAATTGAA
    CAATCTGAATCCTTTTCACAAAAAGTAAAAGAAGGTAAAAGCTACCCTCGTATCATTAGC
    GAATTATTAGAGCATCATGAAGCACTAGCAAGTCCTAACAACATACTTGGTATTAGTTAC
    CTGAAAGCAATTGCTAAAAATGCTAAAAACATCAATGCAATTTCTATCAAACGAGAAAAT
    GCTCAACATCATGATTCATTAATTCAACACCATCAGTTTGCAAGTGGTACATCTATTAGA
    ACATCAATCATTAGTCAAGATGATCATTGGCATCATGTGGTACCTAAAGATATTCAACAC
    TTGTACGTAACACCTCATATAACATTAAATCAAATATTTCCATATTTGAAATATCAAATC
    ATAGCTATGACTACAGATTCATTAAAAAATATTTATACTGTTACTGAAGGTTTTGAAAAT
    CGTTTGAAATCTAACATTTATGAAGCAACTGATTTTCATCATTTTGTAAAATTACTAAAA
    ACAAAGCGTTATACATATACGCATATCCAAAGACTGTTAATGAATGTATTATTAAACATT
    AAACCTACAGATGTTACGAGTAACATTCACGCAGTTAAAGTATTAGCGATGAACGACCGT
    GGCAGACAATATTTAAAGCATTTAAAAACAGCGTTCCCAGAAAGACAATATATAACCAAT
    ATTAACAAAAGCAATGCACATTACTTCACAAATGAAATCAAAGCAACACACATATACAAT
    GCAATAAGCGGGCAACAACAAACAGATTTCAACACGCCTGTCATACAGCAATATCGTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SAOUHSC_01076
  • symbol: SAOUHSC_01076
  • description: hypothetical protein
  • length: 379
  • theoretical pI: 9.60936
  • theoretical MW: 43239.9
  • GRAVY: -0.393404

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    cytidyltransferase-like domain (TIGR00125; HMM-score: 26)
    MetabolismBiosynthesis of cofactors, prosthetic groups, and carriersPyridine nucleotidesnicotinamide-nucleotide adenylyltransferase (TIGR01527; EC 2.7.7.1; HMM-score: 17.7)
  • TheSEED:  
    CBSS-269801.1.peg.1715 FIG007079: UPF0348 protein family 
    COG1399 FIG007079: UPF0348 protein family 
  • PFAM:
    HUP (CL0039) HIGH_NTase1; HIGH Nucleotidyl Transferase (PF05636; HMM-score: 403)
    CTP_transf_like; Cytidylyltransferase-like (PF01467; HMM-score: 22.5)
    no clan definedLsmAD; LsmAD domain (PF06741; HMM-score: 15.8)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.13
    • Ymax_pos: 21
    • Cmax: 0.126
    • Cmax_pos: 21
    • Smax: 0.197
    • Smax_pos: 14
    • Smean: 0.115
    • D: 0.124
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MKSVGLITEYNPFHNGHQYHINQSKKLTNADVTIAIMSGNFVMRGEPAIYNKFTRAKMALSTADLVIELPATASLSSGDHFAELAVKVADYMSVDTIAFGSENNDIKTLKQLAHSINEIEQSESFSQKVKEGKSYPRIISELLEHHEALASPNNILGISYLKAIAKNAKNINAISIKRENAQHHDSLIQHHQFASGTSIRTSIISQDDHWHHVVPKDIQHLYVTPHITLNQIFPYLKYQIIAMTTDSLKNIYTVTEGFENRLKSNIYEATDFHHFVKLLKTKRYTYTHIQRLLMNVLLNIKPTDVTSNIHAVKVLAMNDRGRQYLKHLKTAFPERQYITNINKSNAHYFTNEIKATHIYNAISGQQQTDFNTPVIQQYR

Experimental data[edit source | edit]

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SAOUHSC_01076 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

  1. Maren Depke, Stephan Michalik, Alexander Rabe, Kristin Surmann, Lars Brinkmann, Nico Jehmlich, Jörg Bernhardt, Michael Hecker, Bernd Wollscheid, Zhi Sun, Robert L Moritz, Uwe Völker, Frank Schmidt
    A peptide resource for the analysis of Staphylococcus aureus in host-pathogen interaction studies.
    Proteomics: 2015, 15(21);3648-3661
    [PubMed:26224020] [WorldCat.org] [DOI] (I p)
  2. Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet.: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

Relevant publications[edit source | edit]