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NCBI: 03-AUG-2016

Summary[edit source | edit]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_01758
  • pan locus tag?: SAUPAN004254000
  • symbol: SAOUHSC_01758
  • pan gene symbol?: mreD
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SAOUHSC_01758
  • symbol: SAOUHSC_01758
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1659668..1660198
  • length: 531
  • essential: no DEG other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGCGTACACTGTATTATTTTTTGATAGGTATTTTACTATTTTATATAGATACTGCAATT
    GGGCTTCTTATTCCAATGCACATAGGTAAGTTTGAACTTGTATTTGTACCACACCTTACA
    TTTATGTATATTTTAATGATGGTAGTGTATCGTGGCTTTGGCGTATCATTATTGCTCAGC
    ATATTTTTAGGCGTAATGACTGATGTATACTTTGGTAGTATTTATGGAGTGTACTTATTT
    GGCTATATATTGTTTTTAGCACTTATAGATCGATTCTTTAAAATTTTTTACAAAGATCAT
    TCGATGTTATTCATTATTATATTAGCCAGCACCTTATTATTAGAAGTCTATGTGGCATTA
    ATATACGGTATGTTAGGATTCATTCAATTTGATATTATTCATTTTGTAGTCTTTAGATTA
    TTGCCAACATTAATTATGAATTTTGTACTGTTGATTATGCTTTATCCGTTGATTATAAAG
    TTCCTTAAAAAAACAAACAATGACATTGACATGAAACGTCGTCAATGGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    531

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SAOUHSC_01758
  • symbol: SAOUHSC_01758
  • description: hypothetical protein
  • length: 176
  • theoretical pI: 9.52813
  • theoretical MW: 20826.5
  • GRAVY: 1.21989

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Cell structureCell envelopeBiosynthesis and degradation of murein sacculus and peptidoglycanrod shape-determining protein MreD (TIGR03426; HMM-score: 82.4)
  • TheSEED:  
    Cell Division and Cell CycleCell Division and Cell Cycle - no subcategoryBacterial Cytoskeleton Rod shape-determining protein MreD 
    Bacterial Cell Division Rod shape-determining protein MreD 
    CBSS-354.1.peg.2917 Rod shape-determining protein MreD 
  • PFAM:
    Gx_transp (CL0315) MreD; rod shape-determining protein MreD (PF04093; HMM-score: 138.1)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 5
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.086
    • Ymax_pos: 70
    • Cmax: 0.127
    • Cmax_pos: 31
    • Smax: 0.101
    • Smax_pos: 70
    • Smean: 0.04
    • D: 0.068
  • predicted transmembrane helices (TMHMM): 5

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MRTLYYFLIGILLFYIDTAIGLLIPMHIGKFELVFVPHLTFMYILMMVVYRGFGVSLLLSIFLGVMTDVYFGSIYGVYLFGYILFLALIDRFFKIFYKDHSMLFIIILASTLLLEVYVALIYGMLGFIQFDIIHFVVFRLLPTLIMNFVLLIMLYPLIIKFLKKTNNDIDMKRRQW

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

  1. Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet.: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

Relevant publications[edit source | edit]