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Pangenome04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40

NCBI: 10-JUN-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_0065 [new locus tag: SAUSA300_RS00330 ]
  • pan locus tag?: SAUPAN000814000
  • symbol: arcA
  • pan gene symbol?: arcA
  • synonym:
  • product: arginine deiminase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SAUSA300_0065 [new locus tag: SAUSA300_RS00330 ]
  • symbol: arcA
  • product: arginine deiminase
  • replicon: chromosome
  • strand: -
  • coordinates: 73113..74348
  • length: 1236
  • essential: unknown

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGGTACAAGGACCCATTCAAGTAAATAGTGAAATAGGCAAATTGAAAACTGTGTTGTTA
    AAAAGACCAGGAAAAGAATTAGAAAATTTAGTACCTGATCATTTAAGTGGTTTATTATTC
    GATGATATTCCCTACTTAAAAGTTGCACAAGAAGAGCATGACAAATTTGCTCAAACTTTG
    AGAGATGAAGGAATCGAAGTAGTTTATTTAGAAAAACTTGCAGCAGAATCTATTACTGAG
    CCAGAAGTACGCGAGAACTTCATAAACGACATATTAACAGAATCTAAAAAGACAATATTA
    GGTCATGAAACTGAAATTAAAGAATTCTTTTCAAAGTTATCTGACCAAGAACTTGTAAAT
    AAAATCATGGCTGGCGTACGTAAAGAAGAAATTCAACTTGAAACAACCCATTTAGTAGAA
    TATATGGATGATAGATATCCATTTTACTTAGATCCAATGCCCAACCTTTATTTTACAAGA
    GATCCCCAAGCTTCAATTGGTAGAGGAATGACAATTAACAGAATGTATTGGAGAGCACGA
    CGTAGAGAATCTATTTTTATGACATATATACTGAAACATCATCCAAGATTTAAAGATAAA
    GATGTACCAGTATGGTTAGATCGTAACTCACCATTTAATATTGAAGGTGGAGATGAATTA
    GTATTATCGAAAGATGTTTTAGCTATTGGTATATCAGAACGTACATCAGCTCAAGCAATA
    GAAAAGTTAGCACGTAATATTTTCAAAGATGCAAACACAAGTTTTAAAAAAATCGTAGCT
    ATTGAAATACCTAATACACGTACATTTATGCACCTAGATACAGTACTAACTATGATTGAC
    TACGATAAGTTTACAGTACATGCAGCAATATTTAAAGAAGAAAATAATATGAATATATTT
    ACCATAGAACAAAATGATGGTAAGGACGATATAAAAATTACTCGTTCTAGCAAGTTACGT
    GAAACACTTGCTGAAGTTTTAGAAGTAGAAAAAGTGGACTTTATTCCAACAGGTAATGGC
    GACGTTATTGATGGTGCACGTGAACAATGGAATGATGGCTCAAACACATTATGTATTCGA
    CCAGGGGTTGTGGTGACATACGATCGCAACTATGTATCAAACCAACTTTTACGCGACAAA
    GGAATTAAAGTGATTGAAATTACTGGTAGTGAACTTGTACGTGGACGCGGAGGCCCAAGA
    TGTATGAGTCAGCCGTTATTTAGAGAAGATATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1236

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SAUSA300_0065 [new locus tag: SAUSA300_RS00330 ]
  • symbol: ArcA
  • description: arginine deiminase
  • length: 411
  • theoretical pI: 5.18702
  • theoretical MW: 47270.7
  • GRAVY: -0.42944

Function[edit source | edit]

  • reaction:
    EC 3.5.3.6?  ExPASy
    Arginine deiminaseL-arginine + H2O = L-citrulline + NH3
  • TIGRFAM:
    MetabolismEnergy metabolismAmino acids and aminesarginine deiminase (TIGR01078; EC 3.5.3.6; HMM-score: 558.9)
    MetabolismPurines, pyrimidines, nucleosides, and nucleotidesPyrimidine ribonucleotide biosynthesisorotate phosphoribosyltransferase (TIGR01367; EC 2.4.2.10; HMM-score: 12.5)
  • TheSEED:  
    Amino Acids and DerivativesArginine; urea cycle, polyaminesArginine and Ornithine Degradation Arginine deiminase (EC 3.5.3.6) 
    Arginine; urea cycle, polyaminesArginine Deiminase Pathway Arginine deiminase (EC 3.5.3.6) 
  • PFAM:
    GME (CL0197) Amidinotransf; Amidinotransferase (PF02274; HMM-score: 390.2)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.123
    • Ymax_pos: 16
    • Cmax: 0.105
    • Cmax_pos: 58
    • Smax: 0.213
    • Smax_pos: 8
    • Smean: 0.145
    • D: 0.132
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MVQGPIQVNSEIGKLKTVLLKRPGKELENLVPDHLSGLLFDDIPYLKVAQEEHDKFAQTLRDEGIEVVYLEKLAAESITEPEVRENFINDILTESKKTILGHETEIKEFFSKLSDQELVNKIMAGVRKEEIQLETTHLVEYMDDRYPFYLDPMPNLYFTRDPQASIGRGMTINRMYWRARRRESIFMTYILKHHPRFKDKDVPVWLDRNSPFNIEGGDELVLSKDVLAIGISERTSAQAIEKLARNIFKDANTSFKKIVAIEIPNTRTFMHLDTVLTMIDYDKFTVHAAIFKEENNMNIFTIEQNDGKDDIKITRSSKLRETLAEVLEVEKVDFIPTGNGDVIDGAREQWNDGSNTLCIRPGVVVTYDRNYVSNQLLRDKGIKVIEITGSELVRGRGGPRCMSQPLFREDI

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]