NCBI: 10-JUN-2013
Contents
⊟Summary[edit source | edit]
- organism: Staphylococcus aureus USA300_FPR3757
- locus tag: SAUSA300_0403 [new locus tag: SAUSA300_RS02160 ]
- pan locus tag?: SAUPAN002118000
- symbol: SAUSA300_0403
- pan gene symbol?: ssl9
- synonym:
- product: superantigen-like protein
⊟Genome View[edit source | edit]
⊟Gene[edit source | edit]
⊟General[edit source | edit]
- type: CDS
- locus tag: SAUSA300_0403 [new locus tag: SAUSA300_RS02160 ]
- symbol: SAUSA300_0403
- product: superantigen-like protein
- replicon: chromosome
- strand: +
- coordinates: 455485..456183
- length: 699
- essential: unknown other strains
⊟Accession numbers[edit source | edit]
- Gene ID: 3914104 NCBI
- RefSeq: YP_493117 NCBI
- MicrobesOnline: 1291918 MicrobesOnline
⊟Phenotype[edit source | edit]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit source | edit]
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661ATGAAATTAACAACGATAGCTAAAGCAACATTAGCATTAGGAATATTAACTACAGGTGTG
TTTACAGCAGAAAGTCAAACTGGTCACGCGAAAGTAGAACTTGATGAGACACAACGCAAA
TATTATATCAATATGCTACATCAATACTATTCTGAAGAAAGTTTTGAACCAACAAACATT
AGTGTTAAAAGCGAAGATTACTATGGCTCTAACGTTTTAAACTTTAAACAACGAAATAAA
GCTTTTAAAGTATTTTTACTTGGTGACGATAAAAATAAATATAAAGAAAAAACACATGGC
CTTGATGTCTTTGCAGTACCTGAATTAATAGATATAAAAGGTGGCATATATAGCGTTGGC
GGTATAACAAAGAAAAATGTGAGATCAGTGTTTGGATTTGTAAGTAATCCAAGTCTACAA
GTTAAAAAAGTTGATGCTAAAAATGGCTTTTCGATAAACGAGTTGTTTTTTATTCAAAAG
GAAGAAGTATCATTGAAGGAACTGGACTTTAAAATAAGAAAACTCTTAATCGAAAAATAT
AGATTGTATAAAGGAACGTCTGATAAAGGTAGAATTGTTATCAATATGAAAGACGAAAAG
AAGCATGAAATTGATTTAAGTGAAAAATTAAGTTTTGAACGTATGTTTGATGTAATGGAT
AGTAAGCAAATTAAAAATATTGAAGTGAATTTGAATTAG60
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⊟Protein[edit source | edit]
⊟General[edit source | edit]
- locus tag: SAUSA300_0403 [new locus tag: SAUSA300_RS02160 ]
- symbol: SAUSA300_0403
- description: superantigen-like protein
- length: 232
- theoretical pI: 9.69341
- theoretical MW: 26675.5
- GRAVY: -0.450431
⊟Function[edit source | edit]
- reaction:
- TIGRFAM:
- TheSEED:
- PFAM: OB_enterotoxin (CL0658) SSL_OB; Staphylococcal superantigen-like OB-fold domain (PF09199; HMM-score: 109.3)Ant-toxin_C (CL0386) Stap_Strp_tox_C; Staphylococcal/Streptococcal toxin, beta-grasp domain (PF02876; HMM-score: 39.6)MAP; MAP domain (PF03642; HMM-score: 14.3)no clan definedMRP-S33; Mitochondrial ribosomal subunit S27 (PF08293; HMM-score: 12.5)
⊟Structure, modifications & interactions[edit source | edit]
- domains:
- modifications:
- cofactors:
- effectors:
- protein partners:
⊟Localization[edit source | edit]
- PSORTb: Extracellular
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0
- Extracellular Score: 10
- Internal Helices: 0
- LocateP: N-terminally anchored (No CS)
- Prediction by SwissProt Classification: Membrane
- Pathway Prediction: Sec-(SPI)
- Intracellular Possibility: -0.17
- Signal Peptide Possibility: 1
- N-terminally Anchored Score: 5
- Predicted Cleavage Site: No CleavageSite
- SignalP: Signal peptide length 31 aa
- Ymax: 0.512
- Ymax_pos: 31
- Cmax: 0.411
- Cmax_pos: 31
- Smax: 0.862
- Smax_pos: 20
- Smean: 0.704
- D: 0.587
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit source | edit]
⊟Protein sequence[edit source | edit]
- MKLTTIAKATLALGILTTGVFTAESQTGHAKVELDETQRKYYINMLHQYYSEESFEPTNISVKSEDYYGSNVLNFKQRNKAFKVFLLGDDKNKYKEKTHGLDVFAVPELIDIKGGIYSVGGITKKNVRSVFGFVSNPSLQVKKVDAKNGFSINELFFIQKEEVSLKELDFKIRKLLIEKYRLYKGTSDKGRIVINMKDEKKHEIDLSEKLSFERMFDVMDSKQIKNIEVNLN
⊟Experimental data[edit source | edit]
- experimentally validated: no data available
⊟Expression & Regulation[edit source | edit]
⊟Operon[edit source | edit]
- MicrobesOnline: SAUSA300_0403 no polycistronic organisation predicted
⊟Regulation[edit source | edit]
- sigma factor:
- regulator: SaeR
SaeR (TF) important in Virulence RegPrecise
⊟Transcription pattern[edit source | edit]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit source | edit]
- Aureolib: no data available
⊟Protein stability[edit source | edit]
- half-life: no data available
⊟Biological Material[edit source | edit]
⊟Mutants[edit source | edit]
⊟Expression vector[edit source | edit]
⊟lacZ fusion[edit source | edit]
⊟GFP fusion[edit source | edit]
⊟two-hybrid system[edit source | edit]
⊟FLAG-tag construct[edit source | edit]
⊟Antibody[edit source | edit]
⊟Other Information[edit source | edit]
You are kindly invited to share additional interesting facts.
⊟Literature[edit source | edit]
⊟References[edit source | edit]
⊟Relevant publications[edit source | edit]
Stefan Monecke, Peter Slickers, Ralf Ehricht
Assignment of Staphylococcus aureus isolates to clonal complexes based on microarray analysis and pattern recognition.
FEMS Immunol. Med. Microbiol.: 2008, 53(2);237-51
[PubMed:18507678] [WorldCat.org] [DOI] (P p)