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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_RS09110 [old locus tag: SAUSA300_1669 ]
  • pan locus tag?: SAUPAN004378000
  • symbol: SAUSA300_RS09110
  • pan gene symbol?:
  • synonym:
  • product: alanine--glyoxylate aminotransferase family protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SAUSA300_RS09110 [old locus tag: SAUSA300_1669 ]
  • symbol: SAUSA300_RS09110
  • product: alanine--glyoxylate aminotransferase family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1833575..1834735
  • length: 1161
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_007793 (1833575..1834735) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
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    481
    541
    601
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    721
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    1021
    1081
    1141
    ATGTATTATCATCAACCGTTGTTATTAACACCTGGCCCAACCCCTGTACCTGATGCCATT
    ATGAGAGAAATTCAAGCACCTATGGTTGGTCATCGTTCTAAAGATTTTGAAGACATCGCA
    CAACAAGCATTTCAAGGTCTAAAGCCAATATTTGGGAGTCAAAATGATGTACTTATTTTA
    ACATCTAGCGGTACAAGCGTCTTGGAGGCTAGTATGTTGAACATTGTAAACCCTGAAGAT
    CACTTCGTTGTCATTGTTTCAGGTGCCTTTGGTAACCGATTTAAACAAATTGCACAAACT
    TATTACAAAAATGTGCATATTTATGACGTAACATGGGGAGAAGCTGTAGATGTCAAAGAT
    TTCATCAATTTCCTTTCAACTTTAAATGTTGAAGTTAAAGCAGTATTTAGTCAATATTGC
    GAAACATCTACGACAGTGCTACACCCTATTCACGAGTTAGGAAATGCCATTAATCAATTT
    AATAGTAATATTTATTTTGTAGTTGACGGCGTAAGTTGCATTGGTGCTGTTGATGTTGAC
    ATTAACAAAGATAAAATTGATGTACTTGTTTCTGGTAGTCAAAAAGCAATTATGTTACCT
    CCAGGATTAGCTTTTGTAGCTTATAGCCACCGTGCAAAAGAACATTTCAAAGAAGTAACT
    ACGCCAAAATTTTATCTAGACTTAAATAAATACATTTCGTCACAAGCTGACAATTCTACA
    CCGTTCACACCAAATGTGTCTTTATTTAGAGGTGTAAATGCATACGTTGAAACCGTAAAA
    GCAGAAGGTTTCAATCACGTAATAGCACGACACTATGCAATTAGAAATGCATTAAGAAGC
    GCCTTAAAAGCATTAGATTTAACTTTATTAGTCAATGATAAAGATGCATCTCCAACGGTT
    ACAGCATTCAAACCTAATACAAATGATGAAGTGAAAATAATCAAAGATGAACTTAAAAAT
    CGCTTTAAAATAACAATTGCTGGTGGTCAAGGCCATCTTAAAGGTCAAATTTTAAGAATT
    GGTCATATGGGGAAAATTAGTCCTTTCGATATTTTATCGGTAGTATCTGCTTTAGAAATT
    ATTTTAACTGAACACCGTAAAGTTAACTATATCGGTAAAGGTATATCAAAATATATGGAG
    GTTATTCATGAAGCAATTTAA
    60
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    1140
    1161

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SAUSA300_RS09110 [old locus tag: SAUSA300_1669 ]
  • symbol: SAUSA300_RS09110
  • description: alanine--glyoxylate aminotransferase family protein
  • length: 386
  • theoretical pI: 7.24118
  • theoretical MW: 42849.9
  • GRAVY: -0.0124352

Function[edit source | edit]

  • reaction:
    EC 1.12.-.-?  ExPASy
  • TIGRFAM:
    2-aminoethylphosphonate aminotransferase (TIGR03301; EC 2.6.1.-; HMM-score: 171.9)
    MetabolismCentral intermediary metabolismPhosphorus compounds2-aminoethylphosphonate--pyruvate transaminase (TIGR02326; EC 2.6.1.37; HMM-score: 123.9)
    MetabolismAmino acid biosynthesisSerine familyphosphoserine transaminase (TIGR01364; EC 2.6.1.52; HMM-score: 37.7)
    cysteine desulfurase NifS (TIGR03402; EC 2.8.1.7; HMM-score: 32.3)
    Unknown functionEnzymes of unknown specificitycysteine desulfurase family protein (TIGR01977; HMM-score: 28)
    MetabolismBiosynthesis of cofactors, prosthetic groups, and carriersGlutathione and analogsergothioneine biosynthesis PLP-dependent enzyme EgtE (TIGR04343; EC 4.4.-.-; HMM-score: 25.5)
    Genetic information processingDNA metabolismRestriction/modificationcysteine desulfurase DndA (TIGR03235; EC 2.8.1.7; HMM-score: 22)
    cysteine desulfurase, NifS family (TIGR03403; EC 2.8.1.7; HMM-score: 17.3)
    MetabolismBiosynthesis of cofactors, prosthetic groups, and carriersOthercysteine desulfurase, SufS family (TIGR01979; HMM-score: 16.7)
    Genetic information processingProtein synthesistRNA and rRNA base modificationcysteine desulfurase IscS (TIGR02006; EC 2.8.1.7; HMM-score: 13.6)
    MetabolismBiosynthesis of cofactors, prosthetic groups, and carriersOthercysteine desulfurase IscS (TIGR02006; EC 2.8.1.7; HMM-score: 13.6)
  • TheSEED:
  • PFAM:
    PLP_aminotran (CL0061) Aminotran_5; Aminotransferase class-V (PF00266; HMM-score: 137.5)
    Cys_Met_Meta_PP; Cys/Met metabolism PLP-dependent enzyme (PF01053; HMM-score: 13.5)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors: pyridoxal 5'-phosphate
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.67
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 0.15
    • Extracellular Score: 0.17
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.124
    • Ymax_pos: 11
    • Cmax: 0.116
    • Cmax_pos: 36
    • Smax: 0.23
    • Smax_pos: 1
    • Smean: 0.136
    • D: 0.129
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446213560 NCBI
  • RefSeq: WP_000291415 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MYYHQPLLLTPGPTPVPDAIMREIQAPMVGHRSKDFEDIAQQAFQGLKPIFGSQNDVLILTSSGTSVLEASMLNIVNPEDHFVVIVSGAFGNRFKQIAQTYYKNVHIYDVTWGEAVDVKDFINFLSTLNVEVKAVFSQYCETSTTVLHPIHELGNAINQFNSNIYFVVDGVSCIGAVDVDINKDKIDVLVSGSQKAIMLPPGLAFVAYSHRAKEHFKEVTTPKFYLDLNKYISSQADNSTPFTPNVSLFRGVNAYVETVKAEGFNHVIARHYAIRNALRSALKALDLTLLVNDKDASPTVTAFKPNTNDEVKIIKDELKNRFKITIAGGQGHLKGQILRIGHMGKISPFDILSVVSALEIILTEHRKVNYIGKGISKYMEVIHEAI

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SAUSA300_RS09110 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]