NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus USA300_FPR3757
• locus tag: SAUSA300_RS09250 [old locus tag: SAUSA300_1693 ]
• pan locus tag^?: SAUPAN004414000
• symbol: SAUSA300_RS09250
• pan gene symbol^?: —
• synonym:
• product: MBL fold metallo-hydrolase

⊟Gene

⊟General

• type: CDS
• locus tag: SAUSA300_RS09250 [old locus tag: SAUSA300_1693 ]
• symbol: SAUSA300_RS09250
• product: MBL fold metallo-hydrolase
• replicon: chromosome
• strand: -
• coordinates: 1867001..1867843
• length: 843
• essential: unknown

⊟Accession numbers

• Location: NC_007793 (1867001..1867843) NCBI
• MicrobesOnline:

⊟Phenotype

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⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  
  ATGAAAATCGGGGATATATCTATTCATTATCTAAATGGTGGCAATACAAAAATGGATGGC
  GGTGCAATGTTTGGTGTTGTTCCGAAGCCGTTGTGGTCAAAGCAATACAATGCAAATGAA
  CGAAATCAAATCAATTTACCGACACATCCAATTTTGATTCAAACGGCTCAATATAATTTG
  ATTATAGATGCAGGTATTGGTAATGGTAAATTATCTGAAAAGCAATTACGTAATTTTGGA
  GTAGATGAAGAAAGTCATATAATTGCTGATTTGGCAAATTATAATTTAACGCCAAAGGAT
  ATTGATTATGTGCTAATGACACATATGCATTTTGATCATGCTGCCGGTTTGACTGATCAA
  GCAGGACATGCAATTTTTGAAAATGCGATTCATGTTGTGCAACAAGATGAGTGGCATGAG
  TTTATTGCACCTAATATAAGAAGTAAATCAACTTACTGGGATAAGAATAAAGGCGATTAT
  AGTAACAAGTTGATTTTATTCGAAAAACATTTTGAACCGGTTCTGGGTATCAAGATGCAA
  CATAGTGGAGGTCATAGCTTTGGCCACACGATTATTACGATTGAAAGTCAAGGAGATAAA
  GCAGTTCATATGGGTGATATATTCCCAACTACTGCACATAAAAATCCTCTATGGGTAACG
  GCATATGATGATTATCCTATGCAATCGATTCGTGAAAAAGAACGCATGATACCATATTTT
  ATTCAGCAACAATATTGGTTCTTGTTTTATCATGATGAAAACTACTTTGCTGTAAAATAC
  AGCGATAATGGTGAAAACATAGATGCATATATTTTACGTGAAACATTAGTTGATAATAAC
  TAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
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  660
  720
  780
  840
  843
  

⊟Protein

⊟General

• locus tag: SAUSA300_RS09250 [old locus tag: SAUSA300_1693 ]
• symbol: SAUSA300_RS09250
• description: MBL fold metallo-hydrolase
• length: 280
• theoretical pI: 6.06469
• theoretical MW: 32189
• GRAVY: -0.491429

⊟Function

• reaction:
• TIGRFAM:
  Genetic information processingTranscriptionRNA processingribonuclease Z (TIGR02651; EC 3.1.26.11; HMM-score: 19.7)
  Unknown functionEnzymes of unknown specificityquinoprotein relay system zinc metallohydrolase 2 (TIGR04559; EC 3.-.-.-; HMM-score: 17.1)
  and 2 more
  phosphonate metabolism protein PhnP (TIGR03307; HMM-score: 12.8)
  arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein (TIGR03675; HMM-score: 12.8)
• TheSEED:
• PFAM:
  Metallo-HOrase (CL0381) Lactamase_B; Metallo-beta-lactamase superfamily (PF00753; HMM-score: 55.1)
  and 2 more
  Lactamase_B_2; Beta-lactamase superfamily domain (PF12706; HMM-score: 22.2)
  Lactamase_B_3; Beta-lactamase superfamily domain (PF13483; HMM-score: 21.8)

⊟Structure, modifications & interactions

• domains:
• modifications:
• cofactors:
• effectors:
• protein partners:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• LocateP:
• SignalP: no predicted signal peptide
  • Ymax: 0.135
  • Ymax_pos: 39
  • Cmax: 0.132
  • Cmax_pos: 23
  • Smax: 0.231
  • Smax_pos: 31
  • Smean: 0.124
  • D: 0.131
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 446612234 NCBI
• RefSeq: WP_000689580 NCBI
• UniProt:

⊟Protein sequence

• MKIGDISIHYLNGGNTKMDGGAMFGVVPKPLWSKQYNANERNQINLPTHPILIQTAQYNLIIDAGIGNGKLSEKQLRNFGVDEESHIIADLANYNLTPKDIDYVLMTHMHFDHAAGLTDQAGHAIFENAIHVVQQDEWHEFIAPNIRSKSTYWDKNKGDYSNKLILFEKHFEPVLGIKMQHSGGHSFGHTIITIESQGDKAVHMGDIFPTTAHKNPLWVTAYDDYPMQSIREKERMIPYFIQQQYWFLFYHDENYFAVKYSDNGENIDAYILRETLVDNN

⊟Experimental data

• experimentally validated: no data available

⊟Expression & Regulation

⊟Operon

• SAUSA300_RS09250 no polycistronic organisation predicted

⊟Regulation

• sigma factor:
• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Other Information

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